In:
Journal of Applied Toxicology, Wiley, Vol. 37, No. 7 ( 2017-07), p. 825-835
Abstract:
Perinatal BPA exposure can induced epigenetic modification in offspring islet. Maternal folate supplementation can ameliorate perinatal BPA‐induced glucose intolerance and β‐cell dysfunction in the offspring. Perinatal BPA exposure induced DNA hypermethylation of Igf2 in offspring islets which can be counteracted by maternal folate supplementation. The changes of epigenetics in islet may contribute to the protection.
Type of Medium:
Online Resource
ISSN:
0260-437X
,
1099-1263
Language:
English
Publisher:
Wiley
Publication Date:
2017
detail.hit.zdb_id:
1475015-6
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