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  • 1
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    Online Resource
    Lack of genetic association of 5‐ HTR 2 A 102 T/C and ‐1438 A/G polymorphisms with T ourette syndrome in a family‐based association study in a C hinese H an population
    Wiley ; 2016
    In:  Asia-Pacific Psychiatry Vol. 8, No. 1 ( 2016-03), p. 87-91
    Details
    In: Asia-Pacific Psychiatry, Wiley, Vol. 8, No. 1 ( 2016-03), p. 87-91
    Abstract: Our purpose is to investigate whether polymorphisms of 102 T/C and ‐1438 A/G in 5 HTR 2 A are associated with T ourette syndrome ( TS ) in C hinese H an population. Methods A total of 178 TS trios were recruited in this study. After the allelic and genotypic distributions of two polymorphisms were genotyped using polymerase chain reaction and restriction fragment length polymorphism (PCR‐RFLP), we compared their genetic distributions with what is expected with H ardy– W einberg to explore whether there might be an association of these polymorphisms with TS by haplotype relative risk ( HRR ) and transmission disequilibrium test ( TDT ) statistics. Results Our results showed that no significant associations were found between the HTR2A 102 T/C and ‐1438 A/G polymorphisms and TS (for HTR2A 102 T/C : TDT  = 2.041, df = 1, P  = 0.175; HRR  = 1.468, χ 2  = 1.905, P  = 0.168, 95% confidence interval: 0.850–2.535; for HTR2A : ‐1438A/G, TDT  = 0.093, df = 1, P  = 0.819; HRR  = 0.965, χ 2  = 0.018, P  = 0.894, 95% confidence interval: 0.574–1.624). Discussion Our study suggested that the HTR2A 102 T/C and ‐1438 A/G polymorphisms may not be associated with susceptibility to TS , and thus do not play a major role in the development of TS in the C hinese H an population. However, these results need to be confirmed in a larger sample collected from different populations.
    Type of Medium: Online Resource
    ISSN: 1758-5864 , 1758-5872
    URL: Issue
    URL: Article
    DOI: 10.1111/appy.2016.8.issue-1
    DOI: 10.1111/appy.12185
    Language: English
    Publisher: Wiley
    Publication Date: 2016
    detail.hit.zdb_id: 2506343-1
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  • 2
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    The ameliorative effect of Lactobacillus plantarum Y44 oral administration on inflammation and lipid metabolism in obese mice fed with a high fat diet
    Royal Society of Chemistry (RSC) ; 2020
    In:  Food & Function Vol. 11, No. 6 ( 2020), p. 5024-5039
    Details
    In: Food & Function, Royal Society of Chemistry (RSC), Vol. 11, No. 6 ( 2020), p. 5024-5039
    Type of Medium: Online Resource
    ISSN: 2042-6496 , 2042-650X
    URL: Article
    DOI: 10.1039/D0FO00439A
    Language: English
    Publisher: Royal Society of Chemistry (RSC)
    Publication Date: 2020
    detail.hit.zdb_id: 2578152-2
    SSG: 21
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  • 3
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    Urolithin C, a gut metabolite of ellagic acid, induces apoptosis in PC12 cells through a mitochondria-mediated pathway
    Royal Society of Chemistry (RSC) ; 2017
    In:  RSC Advances Vol. 7, No. 28 ( 2017), p. 17254-17263
    Details
    In: RSC Advances, Royal Society of Chemistry (RSC), Vol. 7, No. 28 ( 2017), p. 17254-17263
    Type of Medium: Online Resource
    ISSN: 2046-2069
    URL: Article
    DOI: 10.1039/C7RA01548H
    Language: English
    Publisher: Royal Society of Chemistry (RSC)
    Publication Date: 2017
    detail.hit.zdb_id: 2623224-8
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  • 4
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    Production of salidroside and tyrosol in cell suspension cultures of Rhodiola crenulata
    Springer Science and Business Media LLC ; 2013
    In:  Plant Cell, Tissue and Organ Culture (PCTOC) Vol. 114, No. 3 ( 2013-9), p. 295-303
    Details
    In: Plant Cell, Tissue and Organ Culture (PCTOC), Springer Science and Business Media LLC, Vol. 114, No. 3 ( 2013-9), p. 295-303
    Type of Medium: Online Resource
    ISSN: 0167-6857 , 1573-5044
    URL: Article
    DOI: 10.1007/s11240-013-0325-z
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2013
    detail.hit.zdb_id: 1478391-5
    SSG: 12
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  • 5
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    Optimization of extraction and enrichment of phenolics from pomegranate (Punica granatum L.) leaves
    Elsevier BV ; 2013
    In:  Industrial Crops and Products Vol. 42 ( 2013-03), p. 587-594
    Details
    In: Industrial Crops and Products, Elsevier BV, Vol. 42 ( 2013-03), p. 587-594
    Type of Medium: Online Resource
    ISSN: 0926-6690
    URL: Article
    DOI: 10.1016/j.indcrop.2012.06.031
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2013
    detail.hit.zdb_id: 1483245-8
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  • 6
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    Phenolic profiles and antioxidant activities of six Chinese pomegranate ( Punica granatum L.) cultivars
    Informa UK Limited ; 2017
    In:  International Journal of Food Properties Vol. 20, No. sup1 ( 2017-12-18), p. S94-S107
    Details
    In: International Journal of Food Properties, Informa UK Limited, Vol. 20, No. sup1 ( 2017-12-18), p. S94-S107
    Type of Medium: Online Resource
    ISSN: 1094-2912 , 1532-2386
    URL: Article
    DOI: 10.1080/10942912.2017.1289960
    Language: English
    Publisher: Informa UK Limited
    Publication Date: 2017
    detail.hit.zdb_id: 2057781-3
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  • 7
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    More work is needed on cost‐utility analyses of robotic‐assisted surgery
    Wiley ; 2022
    In:  Journal of Evidence-Based Medicine Vol. 15, No. 2 ( 2022-06), p. 77-96
    Details
    In: Journal of Evidence-Based Medicine, Wiley, Vol. 15, No. 2 ( 2022-06), p. 77-96
    Abstract: To comprehensively analyze the cost‐utility of robotic surgery in clinical practice and to investigate the reporting and methodological quality of the related evidence. Methods Data on cost‐utility analyses (CUAs) of robotic surgery were collected in seven electronic databases from the inception to July 2021. The quality of the included studies was assessed using the CHEERs and QHES checklists. A systematic review was performed with the incremental cost‐effectiveness ratio as the outcome of interest. Results Thirty‐one CUAs of robotic surgery were eligible. Overall, the identified CUAs were fair to high quality, and 63% of the CUAs ranked the cost‐utility of robotic surgery as “favored,” 32% categorized as “reject,” and the remaining 5% ranked as “unclear.” Although a high heterogeneity was present in terms of the study design among the included CUAs, most studies (81.25%) consistently found that robotic surgery was more cost‐utility than open surgery for prostatectomy (ICER: $6905.31/QALY to $26240.75/QALY; time horizon: 10 years or lifetime), colectomy (dominated by robotic surgery; time horizon: 1 year), knee arthroplasty (ICER: $1134.22/QALY to $1232.27/QALY; time horizon: lifetime), gastrectomy (dominated by robotic surgery; time horizon: 1 year), spine surgery (ICER: $17707.27/QALY; time horizon: 1 year), and cystectomy (ICER: $3154.46/QALY; time horizon: 3 months). However, inconsistent evidence was found for the cost‐utility of robotic surgery versus laparoscopic surgery and (chemo)radiotherapy. Conclusions Fair or high‐quality evidence indicated that robotic surgery is more cost‐utility than open surgery, while it remains inconclusive whether robotic surgery is more cost‐utility than laparoscopic surgery and (chemo)radiotherapy. Thus, an additional evaluation is required.
    Type of Medium: Online Resource
    ISSN: 1756-5383 , 1756-5391
    URL: Issue
    URL: Article
    DOI: 10.1111/jebm.v15.2
    DOI: 10.1111/jebm.12475
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 2474496-7
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  • 8
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    Transcriptome analysis of genes involved in starch biosynthesis in developing Chinese chestnut (Castanea mollissima Blume) seed kernels
    Springer Science and Business Media LLC ; 2021
    In:  Scientific Reports Vol. 11, No. 1 ( 2021-02-11)
    Details
    In: Scientific Reports, Springer Science and Business Media LLC, Vol. 11, No. 1 ( 2021-02-11)
    Abstract: Chinese chestnut ( Castanea mollissima Blume) seed kernels (CCSK) with high quality and quantity of starch has emerged as a potential raw material for food industry, but the molecular regulatory mechanism of starch accumulation in developing CCSK is still unclear. In this study, we firstly analyzed the fruit development, starch accumulation, and microscopic observation of dynamic accumulation of starch granules of developing CCSK from 10 days after flowering (DAF) to 100 DAF, of which six representative CCSK samples (50–100 DAF) were selected for transcriptome sequencing analysis. Approximately 40 million valid reads were obtained, with an average length of 124.95 bp, which were searched against a reference genome, returning 38,146 unigenes (mean size = 1164.19 bp). Using the DESeq method, 1968, 1573, 1187, 1274, and 1494 differentially expressed unigenes were identified at 60:50, 70:60, 80:70, 90:80 and 100:90 DAF, respectively. The relationship between the unigene transcriptional profiles and starch dynamic patterns in developing CCSK was comparatively analyzed, and the specific unigenes encoding for metabolic enzymes (SUSY2, PGM, PGI, GPT, NTT, AGP3, AGP2, GBSS1, SS1, SBE1, SBE2.1, SBE2.2, ISA1, ISA2, ISA3, and PHO) were characterized to be involved potentially in the biosynthesis of G-1-P, ADPG, and starch. Finally, the temporal transcript profiles of genes encoding key enzymes ( susy2 , pgi2 , gpt1 , agp2 , agp3 , gbss1 , ss1, sbe1, sbe2.1, sbe2.2, isa1, isa2, isa3 , and pho ) were validated by quantitative real-time PCR (qRT-PCR). Our findings could help to reveal the molecular regulatory mechanism of starch accumulation in developing CCSK and may also provide potential candidate genes for increasing starch content in Chinese chestnut or other starchy crops.
    Type of Medium: Online Resource
    ISSN: 2045-2322
    URL: Article
    DOI: 10.1038/s41598-021-82130-6
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2021
    detail.hit.zdb_id: 2615211-3
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  • 9
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    On the Entropy and the Maximum Entropy Principle of Uncertain Variables
    MDPI AG ; 2023
    In:  Entropy Vol. 25, No. 8 ( 2023-08-11), p. 1195-
    Details
    In: Entropy, MDPI AG, Vol. 25, No. 8 ( 2023-08-11), p. 1195-
    Abstract: A new variance formula is developed using the generalized inverse of an increasing function. Based on the variance formula, a new entropy formula for any uncertain variable is provided. Most of the entropy formulas in the literature are special cases of the new entropy formula. Using the new entropy formula, the maximum entropy distribution for unimodel entropy of uncertain variables is provided without using the Euler–Lagrange equation.
    Type of Medium: Online Resource
    ISSN: 1099-4300
    URL: Article
    DOI: 10.3390/e25081195
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2014734-X
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  • 10
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    Automatic Design Method and Application in Complex Ship Block Lifting
    The Society of Naval Architects and Marine Engineers ; 2017
    In:  Journal of Ship Production and Design Vol. 33, No. 04 ( 2017-11-1), p. 283-290
    Details
    In: Journal of Ship Production and Design, The Society of Naval Architects and Marine Engineers, Vol. 33, No. 04 ( 2017-11-1), p. 283-290
    Abstract: The traditional block lifting schemes often give rise to a host of problems such as the complexity of the lifting process, low degree of automation, and lack of theoretical guidance. To overcome the deficiencies, the authors of this paper have developed an automatic design system for the complex block lifting. Tribon is adopted as the data extraction method to identify the feature area of a block so as to lay out the lifting lugs properly and efficiently. Besides, Matlab is employed to analyze the stress on lifting wires and 3ds Max to simulate the block lifting process. In this way, the potential problems about mechanics and interference between the block and wires can be forecasted so as to enable the designers to improve the lifting scheme and ensure a safer and more reliable design. 1. Introduction Block lifting operation is a crucial process in shipbuilding since it determines the efficiency of the hull construction as well as the quality of the ship. The traditional artificial block lifting schemes often entail a host of problems such as the complexity of the lifting process, low degree of automationand lack of theoretical guidance. in recent years, scholars have studied the block lifting technologies for several types of ships including Very Large crude carrier (VLcc) and the container vessel. After analyzing the features of block lifting operation and the lifting environment, Li et al. (2013) summarized the principles and requirements of block lifting design, built models for the object to be lifted for the lifting equipment as well, designed an automatic layout algorithm for block lifting scheme and developed a design system for ship block lifting. Li et al. (2014) rebuilt the finite element model under ANSYS environment based on the extracted data of blocks. The calculation results can serve as a guidance for the design of structural reinforcement, which can save materials and reduce workload. In terms of the block lifting technologies used in the building of a 3500 TEU container vessel, Zhang (2010) studied on the lifting technologies employed in lifting some typical blocks such as the stern, broadside, and engine room. Based on the analysis and study on hull assembly method, Yu (2014) took use of computer to successfully simulate the process of hull assembly and save the relevant process information about the hull before shipbuilding. Kim et al. (2005) developed the virtual assembly simulation system for shipbuilding, which can simulate the operation of cranes and the installation of blocks in a virtual shipyard and evaluate the operations. Miura (2011) adopted the three-dimensional computer Aided Design (cAD) to develop a simulation system for block lifting and then he illustrated the features and functions of the system and stressed the importance of threedimensional model used in the process. Takola et al. (2013) established a mathematical model to analyze the constraint conditions in the block lifting process so as to optimize the lifting scheme and improve the efficiency of lifting operations. By applying the theory of combined discrete event and discrete time, Cha J.H. developed an integrated simulation framework for block lifting and erection process (Cha et al. 2010; Cha & Roh 2010). KuN. developed a crane system consists of several crane types, a scenario manager capable of creating and editing lifting process for multibody dynamics-based simulation is proposed (Ku et al. 2014a, 2014b). This study focuses on the complex ship block lifting with an attempt to build a system integrating the design of the complex block lifting scheme, the analysis on the mechanical characteristics in the lifting process and the simulation design of the block lifting operation together (Fig. 1).
    Type of Medium: Online Resource
    ISSN: 2158-2866 , 2158-2874
    URL: Article
    DOI: 10.5957/JSPD.150020
    Language: English
    Publisher: The Society of Naval Architects and Marine Engineers
    Publication Date: 2017
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