In:
Advanced Synthesis & Catalysis, Wiley, Vol. 360, No. 7 ( 2018-04-03), p. 1352-1357
Abstract:
An approach for the synthesis of α‐aryl alkylphosphonates based on visible‐light photocatalytic Giese reaction of α‐aryl vinylphosphonates with aliphatic carboxylic acids has been successfully developed. This protocol tolerates a wide range of functional groups and shows broad substrate scope with regard to both the carboxylic acid and vinylphosphonate components. With sequential Giese/hydrolysis reactions as the strategy, the oxo‐phosphonates could be easily accessible. The synthetic application of the hydroformylation reaction was demonstrated by the synthesis of the intermediate of α‐phenyl substituted fosmidomycin analogue. Furthermore, the competitive decarboxylative alkylation of vinylphosphonate and acrylate was also investigated. magnified image
Type of Medium:
Online Resource
ISSN:
1615-4150
,
1615-4169
DOI:
10.1002/adsc.201701285
Language:
English
Publisher:
Wiley
Publication Date:
2018
detail.hit.zdb_id:
2041384-1
detail.hit.zdb_id:
2033084-4
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