In:
Asian Journal of Organic Chemistry, Wiley, Vol. 8, No. 12 ( 2019-12), p. 2201-2204
Abstract:
A palladium‐catalyzed cascade reaction involving domino Heck/intramolecular C−H arylation to construct 2,3,9,9 a ‐tetrahydro‐1 H ‐fluorene derivatives was developed. Products are obtained in moderate to excellent yields. The transient σ‐alkylpalladium(II) complex is the key intermediate, which mediates the C(sp 2 )‐H bond activation via a six‐metallacycle. According to a transient σ‐alkylpalladium(II) complex, the control experiment demonstrates that β‐H elimination is faster than C−H activation. The methodology shows high chemoselectivity and good functional group tolerance.
Type of Medium:
Online Resource
ISSN:
2193-5807
,
2193-5815
DOI:
10.1002/ajoc.201900600
Language:
English
Publisher:
Wiley
Publication Date:
2019
detail.hit.zdb_id:
2679333-7
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