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  • 1
    In: BMJ Open, BMJ, Vol. 13, No. 12 ( 2023-12), p. e078917-
    Abstract: This work aimed to analyse the risk factors for poor outcomes and mortality among patients with anterior large vessel occlusion (LVO) ischaemic stroke, despite successful recanalisation. Setting and participants This study conducted a secondary analysis among patients who underwent successful recanalisation in the CAPTURE trial. The trial took place between March 2018 and September 2020 at 21 sites in China. The CAPTURE trial enrolled patients who had an acute ischaemic stroke aged 18–80 years with LVO in anterior circulation. Interventions Thrombectomy was immediately performed using Neurohawk or the Solitaire FR after randomisation in CAPTURE trial. Rescue treatment was available for patients with severe residual stenosis caused by atherosclerosis. Primary and secondary outcome measures The primary goal was to predict poor 90-day survival or mortality within 90 days post-thrombectomy. Univariate analysis, using the χ 2 test or Fisher’s exact test, was conducted for each selected factor. Subsequently, a multivariable analysis was performed on significant factors (p≤0.10) identified through univariate analysis using the backward selection logistic regression approach. Results Among the 207 recruited patients, 79 (38.2%) exhibited poor clinical outcomes, and 26 (12.6%) died within 90 days post-thrombectomy. Multivariate analysis revealed that the following factors were significantly associated with poor 90-day survival: age ≥67 years, internal carotid artery (ICA) occlusion (compared with middle cerebral artery (MCA) occlusion), initial National Institutes of Health Stroke Scale (NIHSS) score ≥17 and final modified Thrombolysis in Cerebral Infarction (mTICI) score 2b (compared with mTICI 3). Additionally, the following factors were significantly associated with mortality 90 days post-thrombectomy: initial NIHSS score ≥17, ICA occlusion (compared with MCA occlusion) and recanalisation with more than one pass. Conclusions Age, NIHSS score, occlusion site, mTICI score and the number of passes can be independently used to predict poor 90-day survival or mortality within 90 days post-thrombectomy. Trial registration number NCT04995757 .
    Type of Medium: Online Resource
    ISSN: 2044-6055 , 2044-6055
    Language: English
    Publisher: BMJ
    Publication Date: 2023
    detail.hit.zdb_id: 2599832-8
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  • 2
    In: IOP Conference Series: Earth and Environmental Science, IOP Publishing, Vol. 332, No. 2 ( 2019-10-01), p. 022015-
    Abstract: In order to clarify the micropore pore structure characteristics of medium and high rank coal reservoirs, based on low temperature CO 2 adsorption test and surface/volume fractal theory, the structure and fractal characteristics of medium and high coal rank micropores (0.40∼2nm) were analyzed. The results show that with the increase of coal metamorphism, the pore size of coal reservoirs changes from 0.55∼0.8nm to 0.5∼0.7nm, and the pore size is 0.5∼0.9nm. Microporous pores have good fractal characteristics, D av1 〈 D av2 indicating stage the pore volume heterogeneity increases with the pore size in the pore range. Dav2 is positively correlated with the maximum vitrinite reflectance, indicating that the pore volume heterogeneity increases with the pore size in the micropore range. The heterogeneity of the surface area of the adsorption pore is far more complicated than the volume heterogeneity, D as1 〈 D as2 ⩾D as3 , indicating that the surface heterogeneity of the micropore decreases with the decrease of the pore size and tends to be stable; As the degree of metamorphism of coal increases. And the study shows that the influence of coal rank on surface heterogeneity decreases with the decrease of pore size.
    Type of Medium: Online Resource
    ISSN: 1755-1307 , 1755-1315
    Language: Unknown
    Publisher: IOP Publishing
    Publication Date: 2019
    detail.hit.zdb_id: 2434538-6
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  • 3
    In: Geoenergy Science and Engineering, Elsevier BV, Vol. 228 ( 2023-09), p. 212020-
    Type of Medium: Online Resource
    ISSN: 2949-8910
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2023
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  • 4
    In: Ecosystems, Springer Science and Business Media LLC, Vol. 22, No. 8 ( 2019-12), p. 1869-1885
    Type of Medium: Online Resource
    ISSN: 1432-9840 , 1435-0629
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2019
    detail.hit.zdb_id: 1478731-3
    SSG: 12
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  • 5
    In: Atmospheric Measurement Techniques, Copernicus GmbH, Vol. 10, No. 3 ( 2017-03-30), p. 1259-1267
    Abstract: Abstract. Closed-path eddy-covariance (EC) systems are used to monitor exchanges of trace gases (e.g., carbon dioxide [CO2], water vapor [H2O], nitrous oxide and methane) between the atmosphere and biosphere. Traditional EC-intake systems are equipped with inline filters to prevent airborne dust particulate from contaminating the optical windows of the sample cell which causes measurement degradation. The inline filter should have a fine pore size (1 to 20 µm is common) to adequately protect the optics and a large filtration surface area to extend the time before it clogs. However, the filter must also have minimal internal volume to preserve good frequency response. This paper reports test results of the field performance of an EC system (EC155, Campbell Scientific, Inc., Logan Utah, USA) with a prototype vortex intake replacing the inline filter of a traditional EC system. The vortex-intake design is based on fluid dynamics theory. An air sample is drawn into the vortex chamber, where it spins in a vortex flow. The initially homogenous flow is separated when particle momentum forces heavier particles to the periphery of the chamber, leaving a much cleaner airstream at the center. Clean air (75 % of total flow) is drawn from the center of the vortex chamber, through a tube, to the sample cell where it is exposed to the optical windows of the gas analyzer. The remaining 25 % of the flow carries the heavier dust particles away through a separate bypass tube. An EC155 system measured CO2 and H2O fluxes in two urban-forest ecosystems in the megalopolis of Beijing, China. These sites present a challenge for EC measurements because of the generally poor air quality which has high concentrations of suspended particulate. The closed-path EC system with vortex intake significantly reduced maintenance requirements by preserving optical signal strength and sample-cell pressure within acceptable ranges for much longer periods. The system with vortex intake also maintained an excellent frequency response. For example, at the Badaling site, the amount of system downtime attributed solely to clogged filters was reduced from 26 % with traditional inline filters to 0 % with the prototype vortex intake. The use of a vortex intake could extend the geographical applicability of the EC technique in ecology and allow investigators to acquire more accurate and continuous measurements of trace-gas fluxes in a wider range of ecosystems.
    Type of Medium: Online Resource
    ISSN: 1867-8548
    Language: English
    Publisher: Copernicus GmbH
    Publication Date: 2017
    detail.hit.zdb_id: 2505596-3
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  • 6
    Online Resource
    Online Resource
    Frontiers Media SA ; 2022
    In:  Frontiers in Neurology Vol. 13 ( 2022-5-17)
    In: Frontiers in Neurology, Frontiers Media SA, Vol. 13 ( 2022-5-17)
    Abstract: Stent placement is a feasible approach worldwidely for patients with symptomatic intracranial artery stenosis (sICAS) and hemodynamic impairment (HI) who are at high risk of recurrent stroke after medical treatment. Exploration of factors associated with poor outcomes after stent placement could help develop better individualized therapeutic strategies. Methods This study conducted a post-hoc analysis of a prospective, multicenter registry study of stent use for sICAS with HI in China. Patient and clinical demographics, and stenotic lesion images were analyzed using univariate and multivariate Cox regression to the time until any endpoints or the end of the follow-up period. The short-term endpoint included any transient ischemic attack (TIA), stroke, or death within 1 month after stent placement. The long-term endpoints included the short-term endpoints and any TIA or stroke in the region of the affected artery that occurred more than 1 month after stent placement. Results Two hundred and ninety two patients were included, with 13 short-term and 39 long-term endpoints. Multivariate Cox regression analysis revealed that lesions at the arterial origin or bifurcation (Hazard Ratio (HR) = 7.52; 95% CI, 1.89–29.82; p = 0.004) were significantly associated with higher short-term risk. Baseline renal insufficiency reduced the risk (HR = 0.08; 95% CI: 0.01–0.68; p = 0.021). Factors significantly associated with higher long-term risk included irregular or ulcerated plaques at the lesion (HR = 2.15; 95% CI: 1.07–4.33; p = 0.031). Subgroup analyses indicated that higher risk occurred in the older age group (age & gt;59 years, HR = 3.73, 95% CI: 1.27–10.97, p = 0.017), and not in the younger group (age≤59 years, HR = 1.12, 95% CI: 0.42–3.03, p = 0.822). Conclusion Irregular or ulcerated plaques in older patients and lesions at the arterial opening or bifurcation were more likely to result in adverse endpoints for stent placement during long or short -term follow-up. Investigation of these factors might facilitate the development of individualized therapeutic strategies for this population. Clinical Trial Registration http://www.clinicaltrials.gov , identifier: NCT01968122.
    Type of Medium: Online Resource
    ISSN: 1664-2295
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2564214-5
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  • 7
    Online Resource
    Online Resource
    MDPI AG ; 2023
    In:  Processes Vol. 11, No. 9 ( 2023-08-28), p. 2575-
    In: Processes, MDPI AG, Vol. 11, No. 9 ( 2023-08-28), p. 2575-
    Abstract: Based on the non-linear seepage characteristics of tight reservoirs and the reconstruction mode of vertical wells with actual volume fracturing, a seven-area percolation model for volume fracturing vertical wells in tight reservoirs is established. Laplace transform and Pedrosa transform are applied to obtain analytical solutions of bottom hole pressure and vertical well production under a constant production regime. After verifying the correctness of the model, the influence of the fracture network parameters on the pressure and production is studied. The research results indicate that as the permeability modulus increases, the production of volume fracturing vertical wells decreases. The penetration ratio of the main crack and the half-length of the main crack have a small impact on production, while the diversion capacity of the main crack has a significant impact on the initial production, but it is ultimately limited by the effective volume of the transformation. Under constant pressure conditions, the greater the width and permeability of the ESRV region, the higher the vertical well production rate is. The smaller the aspect ratio of the ESRV region, the higher the mid-term yield and the faster the yield decrease. The research results show guiding significance for the design of vertical well volume fracturing in tight reservoirs.
    Type of Medium: Online Resource
    ISSN: 2227-9717
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2720994-5
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  • 8
    In: Journal of NeuroInterventional Surgery, BMJ, Vol. 12, No. 3 ( 2020-03), p. 274-278
    Abstract: To evaluate the clinical outcomes of early stenting (≤14 days) or late stenting ( 〉 14 days) in patients who underwent intracranial stent placement. Methods Patients with ischemic stroke caused by 70–99% intracranial atherosclerotic stenosis combined with poor collaterals were enrolled. The early stenting group, who underwent stenting within 14 days of last ischemic symptoms, were compared with the late stenting group who underwent stenting 〉 14 days from last ischemic symptom. The patients were treated either with a balloon-mounted stent or a self-expanding stent as determined by the operators following a guideline. The baseline characteristics and clinical outcomes were evaluated and compared. Results One hundred and fifteen stroke patients were recruited into the study. Four patients (4/41) in the early stenting group and two patients (2/74) in the late stenting group were diagnosed with a cerebral vascular event associated with stenting within 3 days (p=0.184). In the long-term follow-up, eight patients in the early stenting group had restenosis ≥50%, which was higher than patients in the late stenting group (8/41 vs 4/74, p=0.018). The total rates of any ischemic stroke, transient ischemic attack, hemorrhagic stroke, and death in the early stenting group were higher than in the late stenting group (9/41 vs 6/74, p=0.035). The recurrence rate of ischemic stroke in the early stenting group was higher than in the late stenting group (5/41 vs 2/74, p=0.041). Conclusions Stent placement in the setting of ischemic stroke caused by intracranial artery stenosis within 14 days may confer a higher risk of long-time cerebral vascular events and lead to a higher risk of restenosis. Clinical trial registration NCT01968122 .
    Type of Medium: Online Resource
    ISSN: 1759-8478 , 1759-8486
    Language: English
    Publisher: BMJ
    Publication Date: 2020
    detail.hit.zdb_id: 2506028-4
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  • 9
    In: Annals of Nuclear Energy, Elsevier BV, Vol. 98 ( 2016-12), p. 120-131
    Type of Medium: Online Resource
    ISSN: 0306-4549
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2016
    detail.hit.zdb_id: 2000768-1
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  • 10
    In: Agricultural and Forest Meteorology, Elsevier BV, Vol. 300 ( 2021-04), p. 108329-
    Type of Medium: Online Resource
    ISSN: 0168-1923
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2021
    detail.hit.zdb_id: 2012165-9
    SSG: 23
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