In:
BMJ Open, BMJ, Vol. 12, No. 7 ( 2022-07), p. e062239-
Abstract:
We aimed to assess the associations between night-time sleep duration and fasting glucose (FG), triglyceride (TG) to high-density lipoprotein cholesterol (HDL-C) ratio and body mass index (BMI) among adults free of type 2 diabetes (T2D) or without diagnosed T2D. Design Cross-sectional study. Setting Medical examination centres at six hospitals in Beijing-Tianjin-Hebei region, China. Participants Participants were recruited via multistage, stratified cluster sampling. We included adults free of T2D or without diagnosed T2D who attended for physical examination and completed the validated questionnaire. 32 497 participants were included in the study, of whom 52.50% were men. Primary and secondary outcome measures FG, TG, HDL-C, height and weight were measured. Results Overall, 12.80% and 9.67% reported night sleep duration 〈 7 hours and ≥9 hours, respectively; 6.91% had elevated FG and 3.57% had undiagnosed T2D. Sleep duration had an independent, U-shaped associated with FG (β 1 (linear term)=−0.111, p=0.047; β 2 (quadratic term)=0.008, p=0.026) with 6.9 hours of sleep associated with the lowest FG and a negative association with BMI (β=−0.154, p 〈 0.001). BMI mediated a U-shaped association of sleep duration with TG/HDL-C (β 1 =−0.040, p=0.017; β 2 =0.003, p=0.023). Conclusions Both short and long night-time sleep was associated with elevated FG, and short sleep duration was associated with increased BMI. BMI mediated a U-shaped association between sleep duration and TG/HDL-C.
Type of Medium:
Online Resource
ISSN:
2044-6055
,
2044-6055
DOI:
10.1136/bmjopen-2022-062239
Language:
English
Publisher:
BMJ
Publication Date:
2022
detail.hit.zdb_id:
2599832-8
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