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  • Wiley  (17)
  • Liu, Chunhong  (17)
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  • Wiley  (17)
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  • 11
    Online Resource
    Online Resource
    Wiley ; 2006
    In:  Journal of Management Studies Vol. 43, No. 5 ( 2006-07), p. 1177-1200
    In: Journal of Management Studies, Wiley, Vol. 43, No. 5 ( 2006-07), p. 1177-1200
    Type of Medium: Online Resource
    ISSN: 0022-2380 , 1467-6486
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2006
    detail.hit.zdb_id: 1473770-X
    SSG: 3,2
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  • 12
    In: Angewandte Chemie International Edition, Wiley, Vol. 62, No. 22 ( 2023-05-22)
    Abstract: Perylene diimide tethered pillar[5]arene derivatives form aggregates in non‐polar organic solvents, and the complexation of cationic amino acid ethyl ester (cAA‐OEt) with the aggregates induce a central‐to‐planar‐to‐helical chirality transfer, leading to intensive circular dichroism (CD) signals having dissymmetric factors ( g abs ) of up to 3.67×10 −2 . The hierarchical chiral induction exhibited an intriguing threshold dose effect, namely, the chiral induction does not occur in the low concentration range of cAA‐OEt but is triggered when cAA‐OEt exceeds a threshold concentration. The inhibited interconversion between the Rp and Sp conformers of pillar[5]arene, which is further restricted in the aggregation, plays a crucial role in the threshold effect. When adding enantiopure cAA‐OEt first to the threshold concentration and then adding an equal amount of the antipodal cAA‐OEt to give cAA‐OEt in racemic form, CD spectra having the same sign as the CD induced by first adding pure cAA‐OEt were induced, thus showing an unprecedented “first come, first served” effect.
    Type of Medium: Online Resource
    ISSN: 1433-7851 , 1521-3773
    URL: Issue
    RVK:
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2011836-3
    detail.hit.zdb_id: 123227-7
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  • 13
    In: Journal of Food Process Engineering, Wiley, Vol. 43, No. 12 ( 2020-12)
    Abstract: In this study, rapeseed oil bodies (RPOBs) were used to prepare curcumin emulsions (CEs) in order to investigate their stability and gastrointestinal. The results showed that particle size significantly reduced ( p  〈 .05) with increasing RPOBs concentrations from 1.0 to 6.0 wt%. Additionally, CEs showed good stability at pH 2.0–10.0. However, CEs were instable at salt concentration ranging from 100 to 500 mM and at temperatures between 35 and 95°C. CE fat droplet size after 30 min of digestion time exhibited a remarkable increase ( p  〈 .05) compared with other times. Upon exposure to simulated intestinal fluid (SIF) conditions, CEs particle sizes gradually decreased with increasing digestion time. Then, 56% curcumin and 40 μmol/ml free fatty acids were produced from CEs after 180 min digestion time under SIF conditions. Practical applications Our findings indicate that rapeseed oil bodies as a novel carrier can be applied for the delivery‐controlled release of lipophilic bioactive compounds from emulsions during gastrointestinal digestion.
    Type of Medium: Online Resource
    ISSN: 0145-8876 , 1745-4530
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2175259-X
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  • 14
    In: Journal of the Science of Food and Agriculture, Wiley, Vol. 101, No. 10 ( 2021-08-15), p. 4173-4182
    Abstract: α ‐lactalbumin ( α ‐La) is of great interest to the industry as a result of its excellent functional properties and nutritional value. Aqueous two‐phase flotation (ATPF) of thermo‐sensitive polymer poly (ethylene glycol‐ran‐propylene glycol) monobutyl ether (UCON) and KH 2 PO 4 was applied to directly separate and purify α ‐La from milk whey, which was purposed to simplify the production process and reduced cost of production. RESULTS The effect of ATPF composition and operating parameters on the flotation efficiency ( E ) and purity of α ‐La were investigated. The optimal conditions included 2 min of premixing time, 30 mL min −1 flow velocity and 20 min of flotation time, whereas the composition conditions comprised 35.0 mL 0.18 g mL −1 phosphate solution (containing 10% (cow milk whey/salt solution, v/v) cow milk whey, 50 ppm defoamer and 2 g NaCl) and 5.0 mL of 40% ( w/w ) UCON solution. Under the optimal conditions, E of α ‐La was 95.67 ± 1.04% and purity of α ‐La was 98.78 ± 1.19%. UCON was recovered by a thermally‐induced phase separation and reused in next ATPF process without reducing E of α ‐La. Purified α ‐La was characterized by several key technologies. The results indicated that α ‐La in cow milk whey could be directly separated and purified by the ATPF and the purity was satisfactory. Moreover, it was suggested there was no obvious structure difference between the α ‐La separated by ATPF and the α ‐La standard. CONCLUSION The present study enabled the recycling of UCON, providing an effective, economically viable and environmentally friendly approach for the separation and purification of protein. © 2021 Society of Chemical Industry
    Type of Medium: Online Resource
    ISSN: 0022-5142 , 1097-0010
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2021
    detail.hit.zdb_id: 2001807-1
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  • 15
    Online Resource
    Online Resource
    Wiley ; 2022
    In:  Biotechnology and Applied Biochemistry Vol. 69, No. 2 ( 2022-04), p. 701-713
    In: Biotechnology and Applied Biochemistry, Wiley, Vol. 69, No. 2 ( 2022-04), p. 701-713
    Abstract: Osteoarthritis (OA) is a common joint disease. Currently, many studies have revealed that circular RNAs (circRNAs) are strongly related to the occurrence and development of diseases. Hence, we aimed to further elucidate the role and molecular mechanism of circRNA SEC24 homolog A, COPII coat complex component (circSEC24A) in OA. Methods Chondrocytes were treated with interleukin‐1β (IL‐1β) to establish OA cell model in vitro. The expression levels of circSEC24A, microRNA‐142‐5p (miR‐142‐5p), and sex‐determining region Y‐box protein 5 (SOX5) were determined by quantitative real‐time polymerase chain reaction. MTT and colony formation assays were used to determine cell proliferation. Cell apoptosis was detected by flow cytometry analysis. The protein levels of inflammatory factors and SOX5 were determined by western blot assay. The relationship between miR‐142‐5p and circSEC24A or SOX5 was confirmed using dual‐luciferase reporter assay and RNA immunoprecipitation assay. Results CircSEC24A and SOX5 expression were enhanced, while miR‐142‐5p level was reduced in OA cartilage tissues and chondrocytes. Overexpression of circSEC24A promoted IL‐1β‐induced injury through decreasing cell proliferation and increasing apoptosis and inflammation in chondrocytes. MiR‐142‐5p was a direct target of circSEC24A, and its upregulation ameliorated IL‐1β‐induced injury and abated the effect of oe‐circSEC24A in IL‐1β‐induced chondrocytes. Additionally, SOX5 was a downstream target of miR‐142‐5p, and its overexpression had a similar role with oe‐circSEC24A and reversed the impact of miR‐142‐5p in IL‐1β‐induced chondrocytes. CircSEC24A acted as a molecular sponge of miR‐142‐5p to regulate SOX5 expression in chondrocytes. Conclusion CircSEC24A aggravated IL‐1β‐induced injury via modulating miR‐142‐5p/SOX5 axis, providing possible targets for the clinical diagnosis and treatment of OA.
    Type of Medium: Online Resource
    ISSN: 0885-4513 , 1470-8744
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 1496341-3
    SSG: 12
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  • 16
    Online Resource
    Online Resource
    Wiley ; 2009
    In:  Journal of Applied Social Psychology Vol. 39, No. 12 ( 2009-12), p. 2879-2909
    In: Journal of Applied Social Psychology, Wiley, Vol. 39, No. 12 ( 2009-12), p. 2879-2909
    Abstract: This study proposes that a shared organizational vision develops cooperative interdependence among departments that, in turn, facilitates cross‐functional teams' organizational citizenship behavior (OCB). Team members indicated their organizations' shared vision, and leaders indicated the goal interdependence among departments and the OCB of the teams. Structural equation analysis suggested that a shared organizational vision shapes goal interdependence among departments that, in turn, affected the OCB of 101 cross‐functional teams. The analysis suggested combining independent and competitive goals, and this combined measure negatively predicted team OCB. These results suggest that a shared organizational vision and cooperative goals among departments are important foundations for cross‐functional teams to contribute to the effective working of organizations through citizenship behavior.
    Type of Medium: Online Resource
    ISSN: 0021-9029 , 1559-1816
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2009
    detail.hit.zdb_id: 2066531-3
    SSG: 5,2
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  • 17
    Online Resource
    Online Resource
    Wiley ; 2020
    In:  Journal of Cellular Biochemistry Vol. 121, No. 2 ( 2020-02), p. 1353-1361
    In: Journal of Cellular Biochemistry, Wiley, Vol. 121, No. 2 ( 2020-02), p. 1353-1361
    Abstract: The aim of this study was to investigate the functional role and the underlying molecular mechanism of long noncoding RNA (lncRNA) prostate cancer–associated transcript 1 (PCAT‐1) in cisplatin resistance of gastric cancer (GC). Our results indicated that PCAT‐1 was overexpressed in CDDP‐resistant GC tumor tissues and cell lines. High expression of PCAT‐1 was closely correlated with short overall survival in patients with GC. Downregulation of PCAT‐1 resensitized CDDP‐resistant GC cells to cisplatin. In addition, PCAT‐1 epigenetically silenced PTEN through binding to the histone methyltransferase enhancer of zeste homolog 2 (EZH2), thus increasing H3K27me3. More importantly, PTEN silencing counteracted PCAT‐1 knockdown–mediated enhancement in cisplatin sensitivity of CDDP‐resistant GC cells. In summary, PCAT‐1 led to cisplatin resistance in GC cells through epigenetically suppressing PTEN expression, providing a novel therapeutic strategy for GC patients with chemoresistance.
    Type of Medium: Online Resource
    ISSN: 0730-2312 , 1097-4644
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 1479976-5
    SSG: 12
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