In:
British Journal of Psychiatry, Royal College of Psychiatrists, Vol. 206, No. 4 ( 2015-04), p. 302-307
Abstract:
Previous evidence has shown positive associations between post-traumatic
stress disorder (PTSD) and hypertension, dyslipidaemia and diabetes mellitus, which are all risk factors for stroke, but the role of PTSD in
the subsequent development of stroke is still unknown. Aims To investigate the temporal association between PTSD and the development
of stroke. Method Identified from the Taiwan National Health Insurance Research Database,
5217 individuals aged 18 years, with PTSD but with no history of stroke, and 20 868 age- and gender-matched controls were enrolled between 2002
and 2009, and followed up until the end of 2011 to identify the development of stroke. Results Individuals with PTSD had an increased risk of developing any stroke
(hazard ratio (HR) 3.37, 95% CI 2.44–4.67) and ischaemic stroke (HR = 3.47, 95% CI 2.23–5.39) after adjusting for demographic data and medical
comorbidities. Sensitivity tests showed consistent findings (any stroke HR = 3.02, 95% CI 2.13–4.28; ischaemic stroke HR = 2.89, 95% CI
1.79–4.66) after excluding the first year of observation. Conclusions Individuals with PTSD have an increased risk of developing any stroke and
ischaemic stroke. Further studies are required to investigate the underlying mechanisms.
Type of Medium:
Online Resource
ISSN:
0007-1250
,
1472-1465
DOI:
10.1192/bjp.bp.113.143610
Language:
English
Publisher:
Royal College of Psychiatrists
Publication Date:
2015
detail.hit.zdb_id:
2021500-9
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