In:
Cell Proliferation, Wiley, Vol. 48, No. 6 ( 2015-12), p. 611-625
Abstract:
The concept of cancer stem cells ( CSC ) has been established over the past decade or so, and their role in carcinogenic processes has been confirmed. In this review, we focus on cervical CSC s, including (1) their purported origin, (2) markers used for cervical CSC identification, (3) alterations to signalling pathways in cervical cancer and (4) the cancer stem cell niche. Although cervical CSC s have not yet been definitively identified and characterized, future studies pursuing them as therapeutic targets may provide novel insights for treatment of cervical cancer.
Type of Medium:
Online Resource
ISSN:
0960-7722
,
1365-2184
DOI:
10.1111/cpr.2015.48.issue-6
Language:
English
Publisher:
Wiley
Publication Date:
2015
detail.hit.zdb_id:
2019986-7
SSG:
12
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