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  • MDPI AG  (2)
  • Lin, Chih-Hung  (2)
  • 2020-2024  (2)
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  • MDPI AG  (2)
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  • 2020-2024  (2)
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  • 1
    In: Cancers, MDPI AG, Vol. 14, No. 1 ( 2021-12-21), p. 15-
    Abstract: (1) Background: The optimal cutoff value that maximizes the prognostic value of surgical margins in patients with resected oral cavity squamous cell carcinoma has not yet been identified. (2) Methods: Data for this study were retrieved from the Taiwan Cancer Registry Database. A total of 13,768 Taiwanese patients with oral cavity squamous cell carcinoma were identified and stratified according to different margin statuses (0, 0.1–4 and 〉 4 mm). The five-year local control, disease-specific survival and overall survival rates were the main outcome measures. (3) Results: The 5-year local control, disease-specific survival and overall survival rates of patients with close margins (0 and 0.1–4 mm) were significantly lower than those observed in patients with clear margins ( 〉 4 mm; all p values 〈 0.001). In multivariate analysis, margin status, depth of invasion and extra-nodal extension were identified as independent adverse prognostic factors for 5-year local control. (4) Conclusions: A thorough assessment of surgical margins can provide a reliable prognostic prediction in patients with OCSCC. This has potential implications for treatment approaches tailored to the individual level. The achievement of clear margins ( 〉 4 mm) should be considered a key surgical goal to improve outcomes in this patient group.
    Type of Medium: Online Resource
    ISSN: 2072-6694
    Language: English
    Publisher: MDPI AG
    Publication Date: 2021
    detail.hit.zdb_id: 2527080-1
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  • 2
    Online Resource
    Online Resource
    MDPI AG ; 2022
    In:  Water Vol. 14, No. 16 ( 2022-08-20), p. 2567-
    In: Water, MDPI AG, Vol. 14, No. 16 ( 2022-08-20), p. 2567-
    Abstract: Although viscous sediment environments along the coast strongly attenuate waves, the attenuation dynamics and physical mechanism governing the attenuation process remain relatively unknown. Extremely complex interactions between muddy seabed have become increasingly important for wave evolution studies pertaining to coastal areas. The coastal protection function of mangroves was confirmed during the 2004 South Asian tsunami. Nevertheless, most research has been limited to macro-qualitative analyses, including those on variations in the transmission coefficient Kt and reflection coefficient Kr, and subsequent comparisons. However, determining the micro-physical characteristics is challenging, similar to coastal vegetation analyses with respect to mangrove vegetation characteristics. This study aims to quantify the attenuation difference in the wave energy owing to the coastal vegetation structure, under different layout conditions and combinations. Particle image velocimetry (PIV) technology is used to explore the variations in the velocity field and velocity distribution during the interaction process and calculate the wave-induced kinetic energy before and after setting up the vegetation structure. The research results emphasize that the resistance and frictional effects generated by vegetation are inversely proportional to the size of the stem, and the variation of kinetic energy determined from the velocity distribution and the thickness of the vegetation stem is mainly due to the larger frictional resistance of dense vegetation, relative to the fast flow velocity above the vegetation. Different vegetation heights slightly affect the short-period waves; however, the impact on energy reduction was smaller. For long-period waves, vegetation height significantly reduces wave kinetic energy.
    Type of Medium: Online Resource
    ISSN: 2073-4441
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2521238-2
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