In:
Advanced Materials Research, Trans Tech Publications, Ltd., Vol. 915-916 ( 2014-4), p. 954-957
Abstract:
To investigate the influence of Schisandrae Chinensis Extract on hepatic injury of rats with microwave. Wistar rats were randomly divided into three groups (control group, microwave radiation group and schisandrae chinensis extract prevention group). Then the rats of schisandrae chinensis extract prevention group were supplyed individually with schisandrae chinensis extract for 5 days before the microwave radiation. After that, the morphology of the livers was observed using HE staining, and the expressions of t-JNK1/2 and p-JNK1/2 were analyzed by western-blotting in the rats. The histological results showed the pathological injury in the liver tissue was improved in all schisandrae chinensis extract prevention groups, and a significant increase of p-JNK1/2 was observed in liver cells after treatment with 200mW/cm 2 microwave for 24 h. It also show that pretreated with schisandrae chinensis extract could inhibit the phosphorylation of JNK1/2. These results suggested that schisandrae chinensis extract could obviously lessened the hepatic injury induced by microwave.
Type of Medium:
Online Resource
ISSN:
1662-8985
DOI:
10.4028/www.scientific.net/AMR.915-916
DOI:
10.4028/www.scientific.net/AMR.915-916.954
Language:
Unknown
Publisher:
Trans Tech Publications, Ltd.
Publication Date:
2014
detail.hit.zdb_id:
2265002-7
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