In:
International Journal of Cancer, Wiley, Vol. 148, No. 6 ( 2021-03-15), p. 1470-1477
Abstract:
Early diagnosis and effective treatment of natural killer/T‐cell lymphoma (NKTL), a rare subtype of non‐Hodgkin lymphoma relatively common in East and Southeast Asian and Central and South American peoples, is an urgent problem. In this multicenter clinical trial, the authors investigated the efficacy of pegaspargase, gemcitabine, cisplatin, and dexamethasone (DDGP) chemotherapy combined with radiotherapy in newly diagnosed stage I‐II NKTL patients. The combined therapy regimen was superior to radiotherapy alone, with progression‐free and overall survival significantly improved in patients receiving DDGP plus radiotherapy. Side effects were mild. The study describes a promising and effective therapeutic alternative for early‐stage NKTL patients.
Type of Medium:
Online Resource
ISSN:
0020-7136
,
1097-0215
Language:
English
Publisher:
Wiley
Publication Date:
2021
detail.hit.zdb_id:
218257-9
detail.hit.zdb_id:
1474822-8
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