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  • Wiley  (72)
  • Li, Wei  (72)
  • 1
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    In vitro Inhibition of bovine enamel demineralization by enamel matrix derivative
    Wiley ; 2014
    In:  Scanning Vol. 36, No. 2 ( 2014-03), p. 194-201
    Details
    In: Scanning, Wiley, Vol. 36, No. 2 ( 2014-03), p. 194-201
    Abstract: This study aimed to determine whether enamel matrix derivative (Emdogain) affects the demineralization of bovine enamel in vitro and to assess the agent's anti‐caries potential. Bovine enamel blocks were prepared and randomly divided into three groups ( n  = 15 per group), which were treated with distilled water (negative control), NaF (positive control), or Emdogain. All three groups were pH‐cycled 12 times over 6 days. The percentage of surface enamel microhardness reduction (%SMHR), calcium demineralization rate (CDR), surface roughness, lesion depth and mineral loss after demineralization were examined. Surface morphology of specimens was studied by scanning electron microscopy. The Emdogain and positive control groups showed similar surface roughness, lesion depths and mineral loss, which were significantly lower than those in the negative control group. In addition, the enamel surfaces of both the Emdogain and NaF groups showed much narrower intercrystalline spaces than the surfaces of the negative control group, which exhibited extensive microfractures along the crystal edges. %SMHR differed significantly among all three groups, with the smallest value in the Emdogain group and the greatest in the negative control group. These results indicate that enamel matrix derivative (Emdogain) can significantly inhibit demineralization of bovine enamel in vitro , suggesting that it has potential as an anti‐caries agent. SCANNING 36:194–201, 2014. © 2013 Wiley Periodicals, Inc.
    Type of Medium: Online Resource
    ISSN: 0161-0457 , 1932-8745
    URL: Issue
    URL: Article
    DOI: 10.1002/sca.v36.2
    DOI: 10.1002/sca.21085
    Language: English
    Publisher: Wiley
    Publication Date: 2014
    detail.hit.zdb_id: 1497198-7
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  • 2
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    NUCLEAR FACTOR‐κB MEDIATES CYTOPROTECTION OF HYDROGEN PEROXIDE PRECONDITIONING AGAINST APOPTOSIS INDUCED BY OXIDATIVE STRESS IN PC12 CELLS
    Wiley ; 2009
    In:  Clinical and Experimental Pharmacology and Physiology Vol. 36, No. 3 ( 2009-03), p. 304-311
    Details
    In: Clinical and Experimental Pharmacology and Physiology, Wiley, Vol. 36, No. 3 ( 2009-03), p. 304-311
    Abstract: Cytoprotection by H 2 O 2 preconditioning against oxidative stress‐induced apoptosis of PC12 cells has been demonstrated previously. In the present study, we investigated the effects of H 2 O 2 preconditioning on nuclear factor (NF)‐κB activation and the role of NF‐κB in the adaptive cytoprotection of H 2 O 2 preconditioning in PC12 cells. The PC12 cells were preconditioned with 100 µmol/L H 2 O 2 for 90 min, followed by 24 h recovery and subsequent exposure to 300 µmol/L H 2 O 2 for a further 12 h. The results showed that preconditioning with 100 µmol/L H 2 O 2 upregulated NF‐κB expression and enhanced its nuclear translocation and DNA binding activity. In addition to its own effects on NF‐κB expression, H 2 O 2 preconditioning also promoted the overexpression of NF‐κB induced by a lethal concentration of H 2 O 2 (300 µmol/L). N ‐Tosyl‐ l ‐phenylalanine chloromethyl ketone (TPCK; 20 µmol/L), an inhibitor of NF‐κB, was administered 20 min before preconditioning with 100 µmol/L H 2 O 2 . At this concenteration, TPCK blocked the overexpression of NF‐κB induced by H 2 O 2 preconditioning, accompanied by attenuation of H 2 O 2 preconditioning‐induced cytoprotection. The inhibition of NF‐κB by TPCK enhanced caspase 3 activity induced by 300 µmol/L H 2 O 2 . 5. The findings of the present study provide novel evidence for the effects of preconditioning with H 2 O 2 on constitutive activation of NF‐κB, which contributes to the adaptive cytoprotection of H 2 O 2 preconditioning against PC12 cells apoptosis.
    Type of Medium: Online Resource
    ISSN: 0305-1870 , 1440-1681
    URL: Issue
    URL: Article
    DOI: 10.1111/cep.2009.36.issue-3
    DOI: 10.1111/j.1440-1681.2008.05066.x
    Language: English
    Publisher: Wiley
    Publication Date: 2009
    detail.hit.zdb_id: 2020033-X
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  • 3
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    Associations between ATG16L1 gene polymorphism and antineutrophil cytoplasmic antibody‐associated vasculitis in the Chinese Guangxi population: A case–control study
    Wiley ; 2022
    In:  Journal of Clinical Laboratory Analysis Vol. 36, No. 9 ( 2022-09)
    Details
    In: Journal of Clinical Laboratory Analysis, Wiley, Vol. 36, No. 9 ( 2022-09)
    Abstract: Antineutrophil cytoplasmic antibody (ANCA)‐associated vasculitis (AAV) is an autoimmune disease often accompanied by rapidly progressive renal failure, and the genetic background is still unknown. Our study was performed to test whether autophagy‐related 16 like 1 ( ATG16L1 ) rs4663402 and rs4663396 single nucleotide polymorphisms (SNPs) were associated with AAV in the Chinese Guangxi population. Methods One hundred seventy seven unrelated AAV patients and 216 healthy controls were included in this case–control study. Multiplex polymerase chain reaction combined with high‐throughput sequencing was used for typing, and SNPStats and SHEsis were used for association analysis, pairwise linkage disequilibrium, and haplotype analysis. Results rs4663402 and rs4663396 were in Hardy–Weinberg equilibrium in AAV and control groups. The frequencies of rs4663402 AA, AT, and TT genotypes were 82.5%, 16.9%, and 0.6%, respectively, in patients with AAV, and 83.5%, 16.2%, and 0.5%, respectively, in controls. The frequencies of rs4663396 CC, CT, and TT genotypes were 63.8%, 33.9%, and 2.3%, respectively, in patients with AAV, and 69.2%, 26.6%, and 4.2%, respectively, in controls. Haplotype analysis revealed two SNPs in a single haplotype block ( D ′ = 1.0). Our logistic regression adjusted for sex and age showed no association between rs4663402 and rs4663396 and the risk for AAV in genetic models ( p   〉  0.05). However, ATG16L1 rs4663396 CC and CT + TT genotypes exhibited statistically significant differences in the incidence of arthralgia ( p  = 0.03). Conclusions Our results indicated that ATG16L1 rs4663402 and rs4663396 polymorphisms were not associated with AAV in the Chinese Guangxi population. ATG16L1 rs4663396 CT + TT genotype may be associated with arthralgia.
    Type of Medium: Online Resource
    ISSN: 0887-8013 , 1098-2825
    URL: Issue
    URL: Article
    DOI: 10.1002/jcla.v36.9
    DOI: 10.1002/jcla.24642
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 2001635-9
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  • 4
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    Discovery of Superconductivity in 2M WS 2 with Possible Topological Surface States
    Wiley ; 2019
    In:  Advanced Materials Vol. 31, No. 30 ( 2019-07)
    Details
    In: Advanced Materials, Wiley, Vol. 31, No. 30 ( 2019-07)
    Abstract: Recently the metastable 1T′‐type VIB‐group transition metal dichalcogenides (TMDs) have attracted extensive attention due to their rich and intriguing physical properties, including superconductivity, valleytronics physics, and topological physics. Here, a new layered WS 2 dubbed “2M” WS 2 , is constructed from 1T′ WS 2 monolayers, is synthesized. Its phase is defined as 2M based on the number of layers in each unit cell and the subordinate crystallographic system. Intrinsic superconductivity is observed in 2M WS 2 with a transition temperature T c of 8.8 K, which is the highest among TMDs not subject to any fine‐tuning process. Furthermore, the electronic structure of 2M WS 2 is found by Shubnikov–de Haas oscillations and first‐principles calculations to have a strong anisotropy. In addition, topological surface states with a single Dirac cone, protected by topological invariant Z 2 , are predicted through first‐principles calculations. These findings reveal that the new 2M WS 2 might be an interesting topological superconductor candidate from the VIB‐group transition metal dichalcogenides.
    Type of Medium: Online Resource
    ISSN: 0935-9648 , 1521-4095
    URL: Issue
    URL: Article
    DOI: 10.1002/adma.v31.30
    DOI: 10.1002/adma.201901942
    RVK:
    UA 1538
    Language: English
    Publisher: Wiley
    Publication Date: 2019
    detail.hit.zdb_id: 1474949-X
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  • 5
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    Biomechanical Evaluation of Preoperative Rehabilitation in Patients of Anterior Cruciate Ligament Injury
    Wiley ; 2020
    In:  Orthopaedic Surgery Vol. 12, No. 2 ( 2020-04), p. 421-428
    Details
    In: Orthopaedic Surgery, Wiley, Vol. 12, No. 2 ( 2020-04), p. 421-428
    Abstract: To investigate the biomechanical characteristics of patients with anterior cruciate ligament (ACL) injury by gait analysis, surface electromyography (SEMG), and proprioception test, and provide rehabilitation suggestions according to the results. Methods In this retrospective cohort study, 90 adults with unilateral ACL injury, ranging in age from 19 to 45 years (66 men and 24 women, average age: 30.03 ± 7.91) were recruited for this study form May 2018 to July 2019. They were divided into three groups according to the time after the injury: group A (3‐week to 1.5‐month), group B (1.5‐month to 1 year), and group C (more than 1 year). The SEMG signals were collected from the bilateral rectus femoris (RF), vastus medialis (VM), and vastus lateralis (VL) and the root mean square (RMS) were used to assess muscular activity. SEMG were used to analyze muscles function, gait analysis was used to evaluate the walking stability, balance and location assessment were used to analyze the proprioception. Results Through the comparison between bilateral limbs, all muscles strength shown decreased (RF: 239.94 ± 129.70 vs 364.81 ± 148.98, P = 0.001; VM: 298.88 ± 175.41 vs 515.79 ± 272.49, P = 0.001; VL:389.54 ± 157.97 vs 594.28 ± 220.31, P 〈  0.001) and the division of proprioception became larger (tandem position: 7.79 ± 1.57 vs 6.33 ± 1.49, P = 0.001; stance with one foot: 8.13 ± 0.84 vs 7.1 ± 0.57, P = 0.003; variance of 30°: 6.96 ± 3.15 vs 4.45 ± 1.67, P = 0.03; variance of 60°: 4.64 ± 3.38 vs 2.75 ± 1.98, P = 0.044) in the injured side when compared to the non‐injured and 26 gait parameters were shown difference in group A. In group B, the muscle strength of VL shown decreased (VL: 381.23 ± 142.07 vs 603.9 ± 192.72, P 〈  0.001) and the division of location of 30° became larger (7.62 ± 4.98 vs 4.33 ± 3.24, P = 0.028) in the injured side when compared to the non‐injured side and there were eight gait parameters that showed differences. In group C, the muscle strength and proprioception showed no differences and only 16 gait parameters showed differences between the bilateral limbs. Conclusion The results proved the deterioration of proprioception in 30° of injured side will not recover and non‐injury side and will become worse after 1 year from the injury; among the VL, VM, and RF, the recovery rate of VL is the slowest and bilateral straight leg raising (SLR) (30°) is the best way to train it; the gait stability will be worse after 1 year from the injury. Therefore, we suggest that the training for proprioception in 30° and VL are important for the rehabilitation, and the ACL reconstruction should be performed within 1 year.
    Type of Medium: Online Resource
    ISSN: 1757-7853 , 1757-7861
    URL: Issue
    URL: Article
    DOI: 10.1111/os.v12.2
    DOI: 10.1111/os.12607
    Language: English
    Publisher: Wiley
    Publication Date: 2020
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  • 6
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    Assessing effect of long‐term abstinence on coupling of three core brain networks in male heroin addicts: A resting‐state functional magnetic resonance imaging study
    Wiley ; 2021
    In:  Addiction Biology Vol. 26, No. 4 ( 2021-07)
    Details
    In: Addiction Biology, Wiley, Vol. 26, No. 4 ( 2021-07)
    Abstract: Abstinence is one of the important measures for heroin addiction. However, it is unknown whether long‐term abstinence (LA) would improve the coupling among three core brain networks (salience, default mode, and executive control) and decrease craving in treated heroin addicts. Forty‐three heroin addicts with LA, 27 heroin addicts with short‐term abstinence (SA), and 46 demographically matched healthy controls (HC) participated in the resting‐state functional magnetic resonance imaging study. The authors compared the functional connectivity among the three groups and examined how the coupling among salience, default mode, and executive control networks related to duration of abstinence and craving before and after drug cue exposure among heroin addicts. Compared with the SA group, with a tendency toward the HC group, the LA group showed lower drug cue‐induced craving, stronger connectivity between the dorsal anterior cingulate cortex (a key node of salience network) and left dorsolateral prefrontal cortex and right posterior parietal cortex (key nodes of executive control network), and stronger connectivity between the right dorsolateral prefrontal cortex and precuneus (a key node of default mode network). Meanwhile, the right dorsolateral prefrontal cortex‐precuneus connectivity positively correlated with duration of abstinence. The LA and SA groups demonstrated lower connectivity between the left anterior insula (a key node of salience network) and dorsolateral prefrontal cortex and lower connectivity within the left dorsolateral prefrontal cortex, compared with the HC group. Our findings revealed that LA is associated with lower drug cue induced craving and improve the coupling among the three core brain networks in heroin addicts.
    Type of Medium: Online Resource
    ISSN: 1355-6215 , 1369-1600
    URL: Issue
    URL: Article
    DOI: 10.1111/adb.v26.4
    DOI: 10.1111/adb.12982
    Language: English
    Publisher: Wiley
    Publication Date: 2021
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  • 7
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    The Effect of CXCR4 Silencing on Epithelial‐Mesenchymal Transition Related Genes in Glioma U87 Cells
    Wiley ; 2013
    In:  The Anatomical Record Vol. 296, No. 12 ( 2013-12), p. 1850-1856
    Details
    In: The Anatomical Record, Wiley, Vol. 296, No. 12 ( 2013-12), p. 1850-1856
    Abstract: The epithelial–mesenchymal transition (EMT) of tumor cells is deemed to be closely associated with tumor metastasis. CXCR4 has been proved to play an important role in the process of tumor metastasis. This study illustrates the function and expression of CXCR4 silencing and the EMT related genes in the human glioma cell line U87. The results showed that CXCR4 silencing could inhibit the cell invasive and adhesion potentials, expression of N‐cadherin, vimentin, β‐catenin, TGF‐β1, p‐Smad2, and p‐Akt, and the activity of transcription factors NF‐κB, AP‐1, Snail, and twist. Meanwhile, CXCR4 silencing could also up‐regulate the expression of E‐cadherin, indicating that silencing of CXCR4 expression can inhibit the expression of EMT related genes in U87 cells. The study would provide a potential theoretical basis for the further exploration of the role of CXCR4 in human glioma. Anat Rec, 296:1850–1856, 2013. © 2013 Wiley Periodicals, Inc.
    Type of Medium: Online Resource
    ISSN: 1932-8486 , 1932-8494
    URL: Issue
    URL: Article
    DOI: 10.1002/ar.v296.12
    DOI: 10.1002/ar.22821
    Language: English
    Publisher: Wiley
    Publication Date: 2013
    detail.hit.zdb_id: 2273240-8
    detail.hit.zdb_id: 2109216-3
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  • 8
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    Two‐year follow‐up of a randomized multicenter study comparing a drug‐coated balloon with a drug‐eluting stent in native small coronary vessels: The RESTORE Small Vessel Disease China trial
    Wiley ; 2020
    In:  Catheterization and Cardiovascular Interventions Vol. 95, No. S1 ( 2020-02), p. 587-597
    Details
    In: Catheterization and Cardiovascular Interventions, Wiley, Vol. 95, No. S1 ( 2020-02), p. 587-597
    Abstract: To report the clinical outcomes of the RESTORE drug‐coated balloon (DCB; Cardionovum, Bonn, Germany) for treatment of de novo small vessel disease (SVD) beyond 1 year. Background Previous reports have demonstrated the noninferiority of the RESTORE DCB to the RESOLUTE Integrity drug‐eluting stent (DES; Medtronic, Minneapolis, Minnesota) in terms of 9‐month in‐segment percent diameter stenosis. Methods In the prospective, multicenter, noninferiority RESTORE SVD China trial, 230 patients with visually‐estimated reference vessel diameter (RVD) ≥2.25 and ≤2.75 mm were randomized to DCB or DES in a 1:1 ratio stratified by diabetes and number of lesions treated. Furthermore, 32 patients with RVD ≥2.00 and 〈 2.25 mm were enrolled in a nested very small vessel (VSV) registry. Clinical follow‐up were performed at 2 years to evaluate target lesion failure (TLF) in both groups and the VSV cohort. Results Overall, 256 (97.7%) patients (115 and 109 in the DCB and DES groups, respectively, and 32 in the VSV cohort) completed 2 years of follow‐up. There was no significant difference in TLF between the DCB and DES groups (5.2 vs. 3.7%, p = .75). Target lesion revascularization was acceptable at 1 month, 1 year, and 2 years, and did not differ significantly with DCB from that in the DES group (0.9 vs. 0%, p = 1.0, 4.4 vs. 2.6%, p = .72, 5.2 vs. 2.8%, p = .50, respectively). Conclusions Compared to the second‐generation DES, the RESTORE DCB did not increase the risk of clinical outcomes. Late catch‐up phenomen requiring revascularization was not significant in this study.
    Type of Medium: Online Resource
    ISSN: 1522-1946 , 1522-726X
    URL: Issue
    URL: Article
    DOI: 10.1002/ccd.v95.S1
    DOI: 10.1002/ccd.28705
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2001555-0
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  • 9
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    Differences in the amplitude of low‐frequency fluctuation between methamphetamine and heroin use disorder individuals: A resting‐state fMRI study
    Wiley ; 2020
    In:  Brain and Behavior Vol. 10, No. 9 ( 2020-09)
    Details
    In: Brain and Behavior, Wiley, Vol. 10, No. 9 ( 2020-09)
    Abstract: Methamphetamine has surpassed heroin as the most popular abused drug in China. Although the use of both heroin and methamphetamine leads to use disorders through dysfunction of the dopamine pathway, the incidence of psychiatric disorder caused by methamphetamine abuse is higher than the incidence of psychiatric disorder caused by heroin abuse. The difference in resting‐state function between heroin use disorder (HUD) and methamphetamine use disorder (MAUD) and the relationship between resting‐state function and psychiatric disorder related to MAUD are unknown. Methods In the present study, 21 male individuals with MAUD, 21 demographically matched individuals with HUD, and 21 normal controls (NC) were recruited. The amplitude of low‐frequency fluctuation (ALFF) during resting‐state brain function was measured by magnetic resonance imaging. Psychiatric status was evaluated by the Symptom Checklist‐90 (SCL90). Results Individuals with MAUD had increased SCL90 scores compared to those of the NC for anxiety, paranoia, and additional items, and the hostility score was significantly increased compared to that of individuals with HUD. There is no significant difference between HUD and NC individuals. Individuals with MAUD had increased ALFF compared to those of the NC for thalamus, right postcentral, and right inferior temporal gyri, but a decreased ALFF in the cerebellum. Individuals with HUD had significantly increased ALFF compared to those of the NC for left middle frontal gyrus but a decreased ALFF in the left postcentral gyrus. Individuals with MAUD had significantly increased ALFF compared to those of the HUD for thalamus, the right inferior temporal, and bilateral postcentral gyri, and the ALFF of cerebellum and left middle frontal was significantly increased. Conclusions Methamphetamine can induce more serious psychiatric disorders than heroin. The resting‐state function involved in mood adjustment, the auditory, and memory‐related brain regions may affect psychotic symptoms related to MAUD.
    Type of Medium: Online Resource
    ISSN: 2162-3279 , 2162-3279
    URL: Issue
    URL: Article
    DOI: 10.1002/brb3.v10.9
    DOI: 10.1002/brb3.1703
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2623587-0
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  • 10
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    Bioactivity‐guided isolation of anti‐inflammatory components from Phyllanthus emblica
    Wiley ; 2020
    In:  Food Science & Nutrition Vol. 8, No. 6 ( 2020-06), p. 2670-2679
    Details
    In: Food Science & Nutrition, Wiley, Vol. 8, No. 6 ( 2020-06), p. 2670-2679
    Abstract: Phyllanthus emblica ( P. emblica ) is a traditionally edible fruit that is good for treatment of biliary diseases, bronchitis, etc. It has obvious anti‐inflammatory activity, but few studies focus on its anti‐inflammatory active substance basis. The purpose of this study was to explore the material basis of anti‐inflammatory activity of P.   emblica , purify, and identify anti‐inflammatory active monomers. Fisetin and gallic acid, which were identified after separation from ethanol extract components of P. emblica , exhibited the best anti‐inflammatory effects, markedly inhibiting nitric oxide and proinflammatory cytokine levels in LPS‐stimulated macrophages. In particular, fisetin with significant anti‐inflammatory activity was firstly identified from P. emblica . For the first time, our research systematically revealed the material basis of the anti‐inflammatory effects of P. emblica from the perspective of the composition of the bioactive substances and provided scientific research methods and ideas for researching bioactive monomers in other plant extracts.
    Type of Medium: Online Resource
    ISSN: 2048-7177 , 2048-7177
    URL: Issue
    URL: Article
    DOI: 10.1002/fsn3.v8.6
    DOI: 10.1002/fsn3.1553
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2703010-6
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