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  • Wiley  (136)
  • Li, Wei  (136)
  • 1
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    Online Resource
    Zinc‐finger protein GmZF351 improves both salt and drought stress tolerance in soybean
    Wiley ; 2023
    In:  Journal of Integrative Plant Biology Vol. 65, No. 7 ( 2023-07), p. 1636-1650
    Details
    In: Journal of Integrative Plant Biology, Wiley, Vol. 65, No. 7 ( 2023-07), p. 1636-1650
    Abstract: Abiotic stress is one of the most important factors reducing soybean yield. It is essential to identify regulatory factors contributing to stress responses. A previous study found that the tandem CCCH zinc‐finger protein GmZF351 is an oil level regulator. In this study, we discovered that the GmZF351 gene is induced by stress and that the overexpression of GmZF351 confers stress tolerance to transgenic soybean. GmZF351 directly regulates the expression of GmCIPK9 and GmSnRK , leading to stomata closing, by binding to their promoter regions, which carry two CT(G/C)(T/A)AA elements. Stress induction of GmZF351 is mediated through reduction in the H3K27me3 level at the GmZF351 locus. Two JMJ30‐demethylase‐like genes, GmJMJ30‐1 and GmJMJ30‐2 , are involved in this demethylation process. Overexpression of GmJMJ30‐1/2 in transgenic hairy roots enhances GmZF351 expression mediated by histone demethylation and confers stress tolerance to soybean. Yield‐related agronomic traits were evaluated in stable GmZF351 ‐transgenic plants under mild drought stress conditions. Our study reveals a new mode of GmJMJ30‐GmZF351 action in stress tolerance, in addition to that of GmZF351 in oil accumulation. Manipulation of the components in this pathway is expected to improve soybean traits and adaptation under unfavorable environments.
    Type of Medium: Online Resource
    ISSN: 1672-9072 , 1744-7909
    URL: Issue
    URL: Article
    DOI: 10.1111/jipb.v65.7
    DOI: 10.1111/jipb.13474
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2130095-1
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  • 2
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    A class B heat shock factor selected for during soybean domestication contributes to salt tolerance by promoting flavonoid biosynthesis
    Wiley ; 2020
    In:  New Phytologist Vol. 225, No. 1 ( 2020-01), p. 268-283
    Details
    In: New Phytologist, Wiley, Vol. 225, No. 1 ( 2020-01), p. 268-283
    Abstract: Soybean ( Glycine max ) production is severely affected in unfavorable environments. Identification of the regulatory factors conferring stress tolerance would facilitate soybean breeding. In this study, through coexpression network analysis of salt‐tolerant wild soybeans, together with molecular and genetic approaches, we revealed a previously unidentified function of a class B heat shock factor, HSFB 2b, in soybean salt stress response. We showed that HSFB 2b improves salt tolerance through the promotion of flavonoid accumulation by activating one subset of flavonoid biosynthesis‐related genes and by inhibiting the repressor gene Gm NAC 2 to release another subset of genes in the flavonoid biosynthesis pathway. Moreover, four promoter haplotypes of HSFB 2b were identified from wild and cultivated soybeans. Promoter haplotype II from salt‐tolerant wild soybean Y20, with high promoter activity under salt stress, is probably selected for during domestication. Another promoter haplotype, III , from salt‐tolerant wild soybean Y55, had the highest promoter activity under salt stress, had a low distribution frequency and may be subjected to the next wave of selection. Together, our results revealed the mechanism of HSFB 2b in soybean salt stress tolerance. Its promoter variations were identified, and the haplotype with high activity may be adopted for breeding better soybean cultivars that are adapted to stress conditions.
    Type of Medium: Online Resource
    ISSN: 0028-646X , 1469-8137
    URL: Issue
    URL: Article
    DOI: 10.1111/nph.v225.1
    DOI: 10.1111/nph.16104
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 208885-X
    detail.hit.zdb_id: 1472194-6
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  • 3
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    Design, Synthesis, and Antifungal Evaluation of Novel Benzoxazole Derivatives Containing a 1,2,3‐Triazole Moiety
    Wiley ; 2017
    In:  Journal of the Chinese Chemical Society Vol. 64, No. 10 ( 2017-10), p. 1197-1202
    Details
    In: Journal of the Chinese Chemical Society, Wiley, Vol. 64, No. 10 ( 2017-10), p. 1197-1202
    Abstract: For finding novel bioactive compounds with significant antifungal activities, 17 novel benzoxazole derivatives containing a 1,2,3‐triazole moiety were synthesized by the copper(II) acetylacetonate‐catalyzed cyclization reaction between 2‐aminophenol derivatives and 1 H ‐1,2,3‐triazole‐4‐carbaldehyde derivatives ( 4a ), which were prepared through three steps using aromatic amine as the starting material. Antifungal activities of the prepared compounds were evaluated against Botrytis cinerea (BC) and Fusarium Verticillium (FV). The test results indicated that compounds 5b , 5c , 5h, and 5n show good inhibitory effects on fungi. The preliminary structure–activity relationship is also discussed.
    Type of Medium: Online Resource
    ISSN: 0009-4536 , 2192-6549
    URL: Issue
    URL: Article
    DOI: 10.1002/jccs.2017.64.issue-10
    DOI: 10.1002/jccs.201700129
    Language: English
    Publisher: Wiley
    Publication Date: 2017
    detail.hit.zdb_id: 2029538-8
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  • 4
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    Assessing effect of long‐term abstinence on coupling of three core brain networks in male heroin addicts: A resting‐state functional magnetic resonance imaging study
    Wiley ; 2021
    In:  Addiction Biology Vol. 26, No. 4 ( 2021-07)
    Details
    In: Addiction Biology, Wiley, Vol. 26, No. 4 ( 2021-07)
    Abstract: Abstinence is one of the important measures for heroin addiction. However, it is unknown whether long‐term abstinence (LA) would improve the coupling among three core brain networks (salience, default mode, and executive control) and decrease craving in treated heroin addicts. Forty‐three heroin addicts with LA, 27 heroin addicts with short‐term abstinence (SA), and 46 demographically matched healthy controls (HC) participated in the resting‐state functional magnetic resonance imaging study. The authors compared the functional connectivity among the three groups and examined how the coupling among salience, default mode, and executive control networks related to duration of abstinence and craving before and after drug cue exposure among heroin addicts. Compared with the SA group, with a tendency toward the HC group, the LA group showed lower drug cue‐induced craving, stronger connectivity between the dorsal anterior cingulate cortex (a key node of salience network) and left dorsolateral prefrontal cortex and right posterior parietal cortex (key nodes of executive control network), and stronger connectivity between the right dorsolateral prefrontal cortex and precuneus (a key node of default mode network). Meanwhile, the right dorsolateral prefrontal cortex‐precuneus connectivity positively correlated with duration of abstinence. The LA and SA groups demonstrated lower connectivity between the left anterior insula (a key node of salience network) and dorsolateral prefrontal cortex and lower connectivity within the left dorsolateral prefrontal cortex, compared with the HC group. Our findings revealed that LA is associated with lower drug cue induced craving and improve the coupling among the three core brain networks in heroin addicts.
    Type of Medium: Online Resource
    ISSN: 1355-6215 , 1369-1600
    URL: Issue
    URL: Article
    DOI: 10.1111/adb.v26.4
    DOI: 10.1111/adb.12982
    Language: English
    Publisher: Wiley
    Publication Date: 2021
    detail.hit.zdb_id: 1495537-4
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  • 5
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    Serum exosomal microRNA let‐7i‐3p as candidate diagnostic biomarker for Kawasaki disease patients with coronary artery aneurysm
    Wiley ; 2019
    In:  IUBMB Life Vol. 71, No. 7 ( 2019-07), p. 891-900
    Details
    In: IUBMB Life, Wiley, Vol. 71, No. 7 ( 2019-07), p. 891-900
    Abstract: Kawasaki disease (KD) is a systemic vasculitis syndrome that leads to coronary artery aneurysm (CAA). While echocardiography is the most important imaging modality for coronary artery assessment, a specific diagnostic biomarker complementary for CAA has not been reported. We aimed to analyze the profiles of exosomal miRNAs extracted from the serum of KD patients and controls to identify candidate biomarkers for CAA. Serum samples from 39 healthy children, 42 CAA patients, 38 coronary artery dilatation (CAD) patients and 45 virus‐infected patients including 24 EBV patients and 21 ADV patients were randomly selected. Next generation sequencing was used to analyze serum exosomal miRNA to detect differentially expressed miRNAs. Biomarker candidates were validated by qRT‐PCR. One hundred (and) ninety‐six differentially expressed miRNAs (DEMs) were detected in CAA patients and healthy children. There were 70 DEMs and 140 DEMs in CAA patients versus CAD patients, and in CAA patients versus virus‐infected patients, respectively. We selected the three most upregulated (let‐7i‐3p, miR‐17‐3p, and miR‐210‐5p) and the three most downregulated miRNAs (miR‐6743‐5p, miR‐1246, and miR‐6834‐5p) in the DEMs, which were expressed differentially in CAA patients versus healthy children, and in CAA patients versus virus‐infected patients, not in virus‐infected patients versus healthy children, as biomarker candidates. Excluded DEMs of CAD and virus‐infected patients, let‐7i‐3p was detected by sequence data analysis as a biomarker candidate for CAA patients, and then validated by qRT‐PCR in a larger set of clinical samples. As a biomarker candidate, let‐7i‐3p provides an additional means of diagnosing CAA patients. Additionally, miRNA biomarkers complement ultrasonic imaging, allowing for greater diagnostic precision. © 2019 IUBMB Life, 2019
    Type of Medium: Online Resource
    ISSN: 1521-6543 , 1521-6551
    URL: Issue
    URL: Article
    DOI: 10.1002/iub.v71.7
    DOI: 10.1002/iub.2015
    Language: English
    Publisher: Wiley
    Publication Date: 2019
    detail.hit.zdb_id: 2009952-6
    detail.hit.zdb_id: 2485214-4
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  • 6
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    Heteroleptic nickel complexes bearing O‐methyldithiophosphate and aminodiphosphine monosulfide ligands as robust molecular electrocatalysts for hydrogen evolution
    Wiley ; 2022
    In:  Applied Organometallic Chemistry Vol. 36, No. 7 ( 2022-07)
    Details
    In: Applied Organometallic Chemistry, Wiley, Vol. 36, No. 7 ( 2022-07)
    Abstract: Five new heteroleptic nickel complexes containing O‐methyldithiophosphate and aminodiphosphine monosulfide ligands, [Ni((PPh 2 )({S}PPh 2 )NR)(S 2 P{O}OCH 3 )] (R = (CH 2 ) 4 CH 3 ( 1 ), (CH 2 ) 3 OCH 3 ( 2 ), (CH 2 ) 3 SCH 3 ( 3 ), (CH 2 ) 2 CH(CH 3 ) 2 ( 4 ), and C 6 H 4 CH 3 –4 ( 5 )), were synthesized by two different methods at room temperature. All complexes were characterized by elemental analysis, spectroscopy ( 1 H, 13 C, 31 P nuclear magnetic resonance [NMR] , and ultraviolet–visible [UV–vis]), single crystal X‐ray diffraction as well as thermogravimetric analysis. In the crystal structures of 1 – 4 and 5 ⋅CH 2 Cl 2 , the nickel atom locates in a slightly distorted square‐planar coordination by one phosphorous atom and three sulfur atoms from the aminodiphosphine monodulfide and O‐meyldithiophosphate ligands. Furthermore, their electrochemical behaviors and electrocatalytic performances for the reduction proton to hydrogen have also been evaluated by the cyclic voltammetry using trifluoroacetic acid (TFA) as the proton source. With the addition of 120 mM TFA to MeCN solution of 1 – 5 (1.0 mM), the turnover frequencies are estimated to be 494–706 s −1 , and the corresponding overpotentials are 0.61–0.70 V versus Fc + /Fc, respectively. This finding diagnoses that the heteroleptic nickel complexes can serve as robust and effective molecular electrocatalysts for hydrogen evolution.
    Type of Medium: Online Resource
    ISSN: 0268-2605 , 1099-0739
    URL: Issue
    URL: Article
    DOI: 10.1002/aoc.v36.7
    DOI: 10.1002/aoc.6725
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 1480791-9
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  • 7
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    Metabolomics study of Angelica sinensis (Oliv.) Diels on the abnormal uterine bleeding rats by ultra‐performance liquid chromatography–quadrupole–time‐of‐flight mass spectrometry analysis
    Wiley ; 2021
    In:  Food Science & Nutrition Vol. 9, No. 12 ( 2021-12), p. 6596-6609
    Details
    In: Food Science & Nutrition, Wiley, Vol. 9, No. 12 ( 2021-12), p. 6596-6609
    Abstract: The objective of this study was to explore the effects and underlying intervention mechanisms of Angelica water extract (AWE) on abnormal uterine bleeding (AUB) based on serum metabolomics. Firstly, the concentration of main active substances in AWE was determined and the chemical components were identified by UPLC‐Q‐Exactive Orbitrap‐MS/MS. A drug‐induced abortion model was established by mifepristone and misoprostol. After administration AWE (2.16 g/kg) for 7 days, the coagulation function, serum hormone levels, H & E staining, and immunohistochemistry observation of uterus were detected. In addition, serum metabolites profiles were performed on ultra‐performance liquid chromatography–quadrupole–time‐of‐flight mass spectrometry (UPLC‐Q‐TOF‐MS). The contents of ferulic acid, senkyunolide A, and ligustilide in AWE were 0.7276, 0.0868, and 1.9908 mg/g, respectively. Twenty‐six compounds were identified in AWE. It was found that AWE was effective in regulation of coagulation function and promoting endometrial recovery. Meanwhile, the levels of E 2 , Pg, and HCG and the expression of ERα, Erβ, and PR were down‐regulated in AUB model and up‐regulated by the treatment of AWE. Twenty‐one potential biomarkers were eventually identified by multivariate statistical analysis. Study indicated that glycerophospholipid, sphingolipid, amino acids, retinol metabolism and primary bile acid biosynthesis were the main related metabolic pathways involved for the treatment of AUB by AWE. The results showed that AWE has potential therapeutic effect on AUB by altering the metabolic aberrations.
    Type of Medium: Online Resource
    ISSN: 2048-7177 , 2048-7177
    URL: Issue
    URL: Article
    DOI: 10.1002/fsn3.v9.12
    DOI: 10.1002/fsn3.2605
    Language: English
    Publisher: Wiley
    Publication Date: 2021
    detail.hit.zdb_id: 2703010-6
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  • 8
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    Association between collaterals, cerebral circulation time and outcome after thrombectomy of stroke
    Wiley ; 2023
    In:  Annals of Clinical and Translational Neurology Vol. 10, No. 2 ( 2023-02), p. 266-275
    Details
    In: Annals of Clinical and Translational Neurology, Wiley, Vol. 10, No. 2 ( 2023-02), p. 266-275
    Abstract: Cerebral circulation time (CCT) and collateral score (CS) are associated with functional outcomes in acute ischemic stroke (AIS) patients after endovascular treatment (EVT), and may be related to each other. We aim to determine the relationship between CS and CCT on functional outcomes. Methods We retrospectively enrolled consecutive patients with anterior circulation large vessel occlusion (LVO) AIS who received EVT. CS and CCT were measured based on digital subtraction angiography (DSA). We defined CS 0–2 and 3–4 as poor and good collateral status, respectively, and used change of CCT (cCCT), which was defined as the change of stroke side CCT (sCCT) versus healthy side CCT (hCCT). Mediating analysis was used to evaluate the influence of cCCT on the association between CS and functional outcomes, and ROC curves were further used to explore the predictive ability of the interaction between cCCT and CS for functional outcomes. Results A total of 100 patients were enrolled in the final analysis. A higher cCCT ( r  = −0.239; p  = 0.017) was associated with lower CS, and cCCT mediated the association of CS with functional outcome. Logistic regression analysis found that CS, cCCT and cCCT‐CS interactions were independently associated with functional outcome, and cCCT‐CS interaction has better predictive performance, with a higher area under curve value than CS or cCCT alone (0.79 vs. 0.75 or 0.75). Interpretation To our knowledge, this study provides the first report of the association of collateral status with cCCT, and their interaction effect on functional outcome in AIS‐LVO patients receiving EVT.
    Type of Medium: Online Resource
    ISSN: 2328-9503 , 2328-9503
    URL: Issue
    URL: Article
    DOI: 10.1002/acn3.v10.2
    DOI: 10.1002/acn3.51718
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2740696-9
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  • 9
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    Rapid measurements of curcumin from complex samples coupled with magnetic biocompatibility molecularly imprinted polymer using electrochemical detection
    Wiley ; 2020
    In:  Journal of Separation Science Vol. 43, No. 6 ( 2020-03), p. 1173-1182
    Details
    In: Journal of Separation Science, Wiley, Vol. 43, No. 6 ( 2020-03), p. 1173-1182
    Abstract: Curcumin widely exists in food, and rapid selective and accurate detection of curcumin have great significance in chemical industry. In this experiment, a new magnetic biocompatibility molecularly imprinted polymer was prepared with nontoxic and biocompatible Zein to adsorb curcumin selectively. The polymer has high biocompatibility, good adsorption capacity, and specific adsorption for curcumin. Combined with portable electrochemical workstations, the polymer can be used to detect curcumin rapidly and cost‐effectively. Using curcumin as a template and Zein as the crosslinking agent, the polymers were synthesized on the surface of Fe 3 O 4 particles for solid phase extraction. The experimental results showed that the polymer reached large adsorption capacity (32.12 mg/g) with fast kinetics (20 min). The adsorption characteristic of the polymer followed the Langmuir isotherm and pseudo‐second‐order kinetic models. Hexacyanoferrate was used as electrochemical probe to generate signals, and the linear range was 5–200 µg/mL for measuring curcumin. The experimental analysis showed that the polymer was an ideal material for selective accumulation of curcumin from complex samples. This approach has been successfully applied to the determination of curcumin in food samples with electrochemical detection, indicating that this is a feasible and practical technique.
    Type of Medium: Online Resource
    ISSN: 1615-9306 , 1615-9314
    URL: Issue
    URL: Article
    DOI: 10.1002/jssc.v43.6
    DOI: 10.1002/jssc.201900884
    RVK:
    VA 5450
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2047990-6
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  • 10
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    Metabolomics analysis of Pulsatilla decoction on treatment of wetness‐heat‐induced diarrhea in rats based on UPLC–Q/TOF–MS/MS
    Wiley ; 2019
    In:  Biomedical Chromatography Vol. 33, No. 11 ( 2019-11)
    Details
    In: Biomedical Chromatography, Wiley, Vol. 33, No. 11 ( 2019-11)
    Abstract: Pulsatilla decoction (PD) is a classical prescription in traditional Chinese medicine that has therapeutic effects on wetness‐heat‐induced diarrhea (WHD). To investigate the therapeutic effects of PD in the treatment of WHD and elucidate the potential mechanism, we used a metabolomics strategy on the base of ultraperformance liquid chromatography coupled with quadrupole time‐of‐flight/mass spectrometry (UPLC–Q/TOF–MS/MS) and analyzed the serum samples of 32 rats to identify differential metabolites and pathways associated with the PD treatment of WHD. With variable importance for projection 〉 1.0 in the Orthogonal partial least‐squares discriminant analysis (OPLS‐DA ) models and FC ≥1.2 or ≤0.8, 67 differential metabolites in the model and control groups and 33 differential metabolites in the model and PD groups were screened. A total of 23 differential metabolites were selected based on Venny analysis. Functional analysis showed that the differential metabolites identified were primarily involved in pentose and glucuronate interconversions, glycerophospholipid metabolism, tryptophan metabolism, starch and sucrose metabolism, and glycerolipid metabolism. This study suggested that PD exerts inhibitory effects on WHD. In particular, the significant roles of PD for treating WHD lie in regulating perturbed energy metabolism, glycerophospholipid metabolism and glycerolipid metabolism, and promoting lysoPC production restoring the function of intestinal tract.
    Type of Medium: Online Resource
    ISSN: 0269-3879 , 1099-0801
    URL: Issue
    URL: Article
    DOI: 10.1002/bmc.v33.11
    DOI: 10.1002/bmc.4629
    Language: English
    Publisher: Wiley
    Publication Date: 2019
    detail.hit.zdb_id: 1479945-5
    SSG: 12
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