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  • Wiley  (50)
  • Li, Ping  (50)
  • 1
    Online Resource
    Online Resource
    Nickel alginate‐enhanced fire safety of aluminum diethylphosphinate on epoxy resin
    Wiley ; 2023
    In:  Journal of Applied Polymer Science Vol. 140, No. 9 ( 2023-03-05)
    Details
    In: Journal of Applied Polymer Science, Wiley, Vol. 140, No. 9 ( 2023-03-05)
    Abstract: To attain superior fire safety epoxy resins (EP), aluminum diethylphosphonate (AlPi) and nickel alginate were incorporated to EP in different proportions. The synergistic flame retardant effects between AlPi and nickel alginate on fire safety and mechanical properties of EP were investigated in detail. EP/AlPi 9.5 ‐Nickel Alginate 0.5 acquired the UL‐94 V‐0 rating with the highest limiting oxygen index value (28.9%). Besides, the thermal decomposition behaviors of the samples were researched by thermogravimetric analysis, implying that EP/AlPi‐Nickel Alginate exhibited the better thermal stability and char‐forming ability. Compared with EP, the peak heat release rate and total heat release were declined by 58.3% and 12.8%. And the addition of nickel alginate reduced the release of smoke. In particular, the incorporation of AlPi and nickel alginate increased the impact strength, flexural strength and glass transition temperature of EP. In perspective, the synergistic effect of bio‐based nickel alginate and AlPi opens a practicable avenue in decreasing the fire risk and improving the mechanical properties of EP.
    Type of Medium: Online Resource
    ISSN: 0021-8995 , 1097-4628
    URL: Issue
    URL: Article
    DOI: 10.1002/app.v140.9
    DOI: 10.1002/app.53552
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 1491105-X
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  • 2
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    Online Resource
    Halogen‐Free Coatings Combined with the Synergistic Effect of Phytic Acid and Montmorillonite for Fire Safety Flexible Polyurethane Foam
    Wiley ; 2022
    In:  Macromolecular Materials and Engineering Vol. 307, No. 5 ( 2022-05)
    Details
    In: Macromolecular Materials and Engineering, Wiley, Vol. 307, No. 5 ( 2022-05)
    Abstract: To overcome defects of some synthetic flame retardants, water‐based coatings using ammonium phytate (AP) and montmorillonite (MMT) as low‐cost renewable materials are fabricated to improve the flame retardancy of flexible polyurethane foam (FPUF). The flame‐retardant FPUF with uniform coatings can avoid melt‐dripping during the vertical flame test (UL‐94), and AP5MMT5/FPUF (flame‐retardant FPUF with the 5:5 weight ratio of AP:MMT in the solutions) reaches a UL‐94 V‐0 rating. A remarkable conclusion can be found that AP and MMT present a synergistic effect under the appropriate proportions. The thermal stabilities of flame retardant FPUF at higher temperature zones are enhanced. Furthermore, flame‐retardant samples prevent the flame from spreading on the surface of FPUF. Cone calorimetry results reveal 67% (AP5MMT5/FPUF) reduction of peak heat release rate relative to pure FPUF, and the release of toxic smoke significantly decreases. AP can catalyze the carbonation of FPUF, and MMT is heated and dehydrated to form a silicon‐containing barrier layer. AP/MMT coatings can form stable and solid physical char layers, which act as a barrier to heat and oxygen exchange, and the release of volatiles is delayed and inhibited. This work introduces a green plan for improving the fire safety of FPUF.
    Type of Medium: Online Resource
    ISSN: 1438-7492 , 1439-2054
    URL: Issue
    URL: Article
    DOI: 10.1002/mame.v307.5
    DOI: 10.1002/mame.202100930
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 2004372-7
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  • 3
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    Synergistic Effects of Iron Alginate on Improving the Fire Safety and Mechanical Properties of Epoxy Resin/Ammonium Polyphosphate Composites
    Wiley ; 2023
    In:  Macromolecular Materials and Engineering Vol. 308, No. 3 ( 2023-03)
    Details
    In: Macromolecular Materials and Engineering, Wiley, Vol. 308, No. 3 ( 2023-03)
    Abstract: Iron alginate is chosen as an eco‐friendly synergist to improve the flame retardancy, smoke suppression, and mechanical properties of epoxy resin/ammonium polyphosphate composites (EP/APP). The suitable additive amount of iron alginate further enhances the char‐forming ability in the higher‐temperature range and flame retardancy of EP/APP. EP/APP 9.0 ‐iron alginate 1.0 retains a char residue of 33.3% at 700 °C and obtains a limiting oxygen index value of 28.4% and vertical burning test (UL‐94) V‐0 rating, while EP/APP 10 has no UL‐94 rating. The burning behaviors of EP/APP 9.0 ‐iron alginate 1.0 are also suppressed; and the total smoke production value is much lower than that of EP/APP 10 . EP/APP 9.0 ‐iron alginate 1.0 releases less smoke and flammable fragments. The suitable additive amount of iron alginate boosts the mechanical properties of EP/APP, while APP destroys the mechanical properties of EP. Therefore, the addition of suitable amount of iron alginates can further reduce the fire hazard, and improve the mechanical properties of EP/APP composites.
    Type of Medium: Online Resource
    ISSN: 1438-7492 , 1439-2054
    URL: Issue
    URL: Article
    DOI: 10.1002/mame.v308.3
    DOI: 10.1002/mame.202200516
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2004372-7
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  • 4
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    Dual effects of atmospheric pressure plasma jet on skin wound healing of mice
    Wiley ; 2015
    In:  Wound Repair and Regeneration Vol. 23, No. 6 ( 2015-11-12), p. 878-884
    Details
    In: Wound Repair and Regeneration, Wiley, Vol. 23, No. 6 ( 2015-11-12), p. 878-884
    Abstract: Cold plasma has become an attractive tool for promoting wound healing and treating skin diseases. This article presents an atmospheric pressure plasma jet (APPJ) generated in argon gas through dielectric barrier discharge, which was applied to superficial skin wounds in BALB/c mice. The mice ( n  = 50) were assigned randomly into five groups (named A, B, C, D, E) with 10 animals in each group. Natural wound healing was compared with stimulated wound healing treated daily with APPJ for different time spans (10, 20, 30, 40, and 50 seconds) on 14 consecutive days. APPJ emission spectra, morphological changes in animal wounds, and tissue histological parameters were analyzed. Statistical results revealed that wound size changed over the duration of the experimental period and there was a significant interaction between experimental day and group. Differences between group C and other groups at day 7 were statistically significant ( p   〈  0.05). All groups had nearly achieved closure of the untreated control wounds at day 14. The wounds treated with APPJ for 10, 20, 30, and 40 seconds showed significantly enhanced daily improvement compared with the control and almost complete closure at day 12, 10, 7, and 13, respectively. The optimal results of epidermal cell regeneration, granulation tissue hyperplasia, and collagen deposition in histological aspect were observed at day 7. However, the wounds treated for 50 seconds were less well healed at day 14 than those of the control. It was concluded that appropriate doses of cold plasma could inactivate bacteria around the wound, activate fibroblast proliferation in wound tissue, and eventually promote wound healing. Whereas, over doses of plasma suppressed wound healing due to causing cell death by apoptosis or necrosis. Both positive and negative effects may be related to the existence of reactive oxygen and nitrogen species (ROS and RNS) in APPJ.
    Type of Medium: Online Resource
    ISSN: 1067-1927 , 1524-475X
    URL: Issue
    URL: Article
    DOI: 10.1111/wrr.2015.23.issue-6
    DOI: 10.1111/wrr.12364
    Language: English
    Publisher: Wiley
    Publication Date: 2015
    detail.hit.zdb_id: 2011990-2
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  • 5
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    Macromol. Biosci. 11/2017
    Wiley ; 2017
    In:  Macromolecular Bioscience Vol. 17, No. 11 ( 2017-11)
    Details
    In: Macromolecular Bioscience, Wiley, Vol. 17, No. 11 ( 2017-11)
    Type of Medium: Online Resource
    ISSN: 1616-5187 , 1616-5195
    URL: Issue
    URL: Article
    DOI: 10.1002/mabi.v17.11
    DOI: 10.1002/mabi.201770041
    Language: English
    Publisher: Wiley
    Publication Date: 2017
    detail.hit.zdb_id: 2039130-4
    SSG: 12
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  • 6
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    Significant difference in active metabolite levels of ginseng in humans consuming Asian or Western diet: The link with enteric microbiota
    Wiley ; 2017
    In:  Biomedical Chromatography Vol. 31, No. 4 ( 2017-04)
    Details
    In: Biomedical Chromatography, Wiley, Vol. 31, No. 4 ( 2017-04)
    Abstract: After ingestion of ginseng, the bioavailability of its parent compounds is low and enteric microbiota plays an important role in parent compound biotransformation to their metabolites. Diet type can influence the enteric microbiota profile. When human subjects on different diets ingest ginseng, their different gut microbiota profiles may influence the metabolism of ginseng parent compounds. In this study, the effects of different diet type on gut microbiota metabolism of American ginseng saponins were investigated. We recruited six healthy adults who regularly consumed different diet types. These subjects received 7 days' oral American ginseng, and their biological samples were collected for LC‐Q‐TOF‐MS analysis. We observed significant ginsenoside Rb 1 (a major parent compound) and compound K (a major active metabolite) level differences in the samples from the subjects consuming different diets. Subjects on an Asian diet had much higher Rb 1 levels but much lower compound K levels compared with those on a Western diet. Since compound K possesses much better cancer chemoprevention potential, our data suggested that consumers on a Western diet should obtain better cancer prevention effects with American ginseng intake compared with those on an Asian diet. Ginseng compound levels could be enhanced or reduced via gut microbiota manipulation for clinical utility.
    Type of Medium: Online Resource
    ISSN: 0269-3879 , 1099-0801
    URL: Issue
    URL: Article
    DOI: 10.1002/bmc.v31.4
    DOI: 10.1002/bmc.3851
    Language: English
    Publisher: Wiley
    Publication Date: 2017
    detail.hit.zdb_id: 1479945-5
    SSG: 12
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  • 7
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    Postoperative dynamic survival of gastric cancer patients: A multi‐institutional, international analysis of 22 265 patients
    Wiley ; 2019
    In:  Journal of Surgical Oncology Vol. 120, No. 4 ( 2019-09), p. 685-697
    Details
    In: Journal of Surgical Oncology, Wiley, Vol. 120, No. 4 ( 2019-09), p. 685-697
    Abstract: How to best evaluate the disease‐specific survival (DSS) of gastric cancer (GC) survivors over time is unclear. Methods Clinicopathological data from 22 265 patients who underwent curative intend resection for GC were retrospectively analyzed. Changes in the patients’ 3‐year conditional disease‐specific survival (CS3) were analyzed. We used time‐dependent Cox regression to analyze which variables had long‐term effects on DSS and devised a dynamic predictive model based on the length of survival. Results Based on 1‐, 3‐, and 5‐year survivorships, the CS3 of the population increased gradually from 62% to 68.1%, 83.7%, and 90.6%, respectively. Subgroup analysis showed that the CS3 of patients who had poor prognostic factors initially demonstrated the greatest increase in postoperative survival time (eg, N3b: 26.6%‐84.1%, Δ57.5% vs N0: 84.1%‐93.3%, Δ9.2%). Time‐dependent Cox regression analysis showed the following predictor variables constantly affecting DSS: age, the number of examined lymph nodes (LNs), T stage, N stage, and site ( P   〈  .05). These variables served as the basis for a dynamic prediction model. Conclusions The influence of prognostic factors on DSS and CS3 changed dramatically over time. We developed an effective model for predicting the DSS of patients with GC based on the length of survival time.
    Type of Medium: Online Resource
    ISSN: 0022-4790 , 1096-9098
    URL: Issue
    URL: Article
    DOI: 10.1002/jso.v120.4
    DOI: 10.1002/jso.25637
    Language: English
    Publisher: Wiley
    Publication Date: 2019
    detail.hit.zdb_id: 1475314-5
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  • 8
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    Preparative separation of four isomers of synthetic anisodamine by HPLC and diastereomer crystallization
    Wiley ; 2019
    In:  Chirality Vol. 31, No. 1 ( 2019-01), p. 11-20
    Details
    In: Chirality, Wiley, Vol. 31, No. 1 ( 2019-01), p. 11-20
    Abstract: Anisodamine (654‐1), a well‐known cholinergic antagonist, is marketed as synthetic anisodamine (mixture of four isomers, 654‐2) in China. To preparative resolution and comparison of the bioactivities of the four isomers of synthetic anisodamine, current work explores an economic and effective separation method by using preparative high performance liquid chromatography (HPLC) and diastereomer crystallization. Their absolute configurations were established by single‐crystal X‐ray diffraction and circular dichroism method. The purities of each isomer were more than 95%. Among them, 654‐2‐A2 (6R, 2′S configuration) exhibited better effect on cabachol preconditioned small intestine tension more than 654‐2 and other isomers. The direct separation method without using HPLC was tried as well, which was still on progress. This is the first report of the method for preparative separation of four isomers of synthetic anisodamine which could be used for large‐scale production in industry.
    Type of Medium: Online Resource
    ISSN: 0899-0042 , 1520-636X
    URL: Issue
    URL: Article
    DOI: 10.1002/chir.v31.1
    DOI: 10.1002/chir.23026
    Language: English
    Publisher: Wiley
    Publication Date: 2019
    detail.hit.zdb_id: 2001237-8
    SSG: 12
    SSG: 15,3
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  • 9
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    Hsa_circ_0000467 promotes cancer progression and serves as a diagnostic and prognostic biomarker for gastric cancer
    Wiley ; 2019
    In:  Journal of Clinical Laboratory Analysis Vol. 33, No. 3 ( 2019-03)
    Details
    In: Journal of Clinical Laboratory Analysis, Wiley, Vol. 33, No. 3 ( 2019-03)
    Abstract: Emerging evidence indicates that dysregulation of circular RNAs (circRNAs) is implicated in the development of malignancies. However, the diagnostic value and functional role of circRNAs in gastric cancer (GC) remain largely elusive. Methods Quantitative reverse transcription‐polymerase chain reaction (qRT‐PCR) was performed to detect the expression of hsa_circ_0000467 in tissues, cell lines, and plasma. A receiver operating characteristic (ROC) curve was constructed to estimate the diagnostic value of hsa_circ_0000467. The association between the expression level of hsa_circ_0000467 and the clinicopathological features was analyzed. Moreover, cell functional assays were performed. Results Hsa_circ_0000467 was significantly upregulated in GC tissue compared to adjacent nontumor tissue (n = 51, P   〈  0.05). Similar results were detected in the HGC‐27, MGC‐803, AGS, NUGC‐3, GES‐1 cell lines (n = 15, P   〈  0.001), and in the plasma samples from GC patients (n = 20, P   〈  0.05). The area under the ROC curve of hsa_circ_0000467 was 0.790, which is superior to commonly used biomarkers including CEA and CA‐724. We found that the expression levels of hsa_circ_0000467 in the same patient were significantly lower after surgery (n = 20, P   〈  0.05). Moreover, the hsa_circ_0000467 expression level is closely associated with TNM stage. Additionally, Cox multivariate analysis showed that hsa_circ_0000467 is a novel independent prognostic factor. Furthermore, in vitro experiments demonstrated that knockdown of hsa_circ_0000467 markedly inhibited the proliferation, migration, and invasion of GC cells. Moreover, hsa_circ_0000467 silencing increased tumor apoptosis in vitro. Conclusion Hsa_circ_0000467 can act as a novel noninvasive biomarker for the diagnosis and prognosis of GC and may be a potential therapeutic target for GC.
    Type of Medium: Online Resource
    ISSN: 0887-8013 , 1098-2825
    URL: Issue
    URL: Article
    DOI: 10.1002/jcla.2019.33.issue-3
    DOI: 10.1002/jcla.22726
    Language: English
    Publisher: Wiley
    Publication Date: 2019
    detail.hit.zdb_id: 2001635-9
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  • 10
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    Prognostic importance of dynamic changes in systemic inflammatory markers for patients with gastric cancer
    Wiley ; 2021
    In:  Journal of Surgical Oncology Vol. 124, No. 3 ( 2021-09), p. 282-292
    Details
    In: Journal of Surgical Oncology, Wiley, Vol. 124, No. 3 ( 2021-09), p. 282-292
    Abstract: To investigate the effect of dynamic changes in systemic inflammatory markers (SIM) on long‐term prognosis of patients with gastric cancer (GC). Methods A retrospective analysis was performed on the data of 2180 patients with GC who underwent radical gastrectomy in the Fujian medical university Union Hospital from January 2009 to December 2014. Changes in SIM between preoperatively and 1–6 months and 12 months postoperatively were reported. Results In multivariate analysis, higher preoperative systemic inflammation score (pre‐SIS) was independent predictor of poor prognosis ( p   〈  0.05). The optimal time of remeasurement was 12 months postoperatively, based on a longitudinal profile of SIS and accuracy in predicting 5‐year overall survival (OS) (area under the curve: 0.712 [95% confidence interval: 0.630–0.785]). According to the association between the conversion of SIS and OS, we classified patients into three risk groups. Kaplan–Meier curves showed significant differences in OS among risk groups. Further Cox multivariate regression analysis showed that only risk groups of SIS and pTNM stage were independent prognostic factors for OS. Conclusion The efficacy of SIS in predicting prognosis 12 months after surgery is superior, and the elevation of SIS 12 months after surgery predicts poor prognosis.
    Type of Medium: Online Resource
    ISSN: 0022-4790 , 1096-9098
    URL: Issue
    URL: Article
    DOI: 10.1002/jso.v124.3
    DOI: 10.1002/jso.26498
    Language: English
    Publisher: Wiley
    Publication Date: 2021
    detail.hit.zdb_id: 1475314-5
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