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  • Hindawi Limited  (4)
  • Li, Jianhua  (4)
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  • Hindawi Limited  (4)
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  • 1
    Online Resource
    Online Resource
    Hindawi Limited ; 2015
    In:  Mathematical Problems in Engineering Vol. 2015 ( 2015), p. 1-6
    In: Mathematical Problems in Engineering, Hindawi Limited, Vol. 2015 ( 2015), p. 1-6
    Abstract: RFID (radio frequency identification) is an emerging technology for automatic identification of physical objects using radio frequency. The security and privacy of the system is increasingly concerned and some light-weight encryption schemes such as Trivium and Bivium have been proposed. In this paper, the internal structure of Bivium is exploited and generalized to an algorithm called Bivium-Model. It is shown that the original Bivium has its inherent imperfections due to the improper parameter selection. A set of better parameters are given out to fix the security vulnerability of original Bivium. Emulation results also show that the Enhanced-Bivium algorithm achieves lower power consumption and lower die size.
    Type of Medium: Online Resource
    ISSN: 1024-123X , 1563-5147
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2015
    detail.hit.zdb_id: 2014442-8
    SSG: 11
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  • 2
    Online Resource
    Online Resource
    Hindawi Limited ; 2016
    In:  Mobile Information Systems Vol. 2016 ( 2016), p. 1-13
    In: Mobile Information Systems, Hindawi Limited, Vol. 2016 ( 2016), p. 1-13
    Abstract: The Intelligent Transportation System (ITS) becomes an important component of the smart city toward safer roads, better traffic control, and on-demand service by utilizing and processing the information collected from sensors of vehicles and road side infrastructure. In ITS, Vehicular Cloud Computing (VCC) is a novel technology balancing the requirement of complex services and the limited capability of on-board computers. However, the behaviors of the vehicles in VCC are dynamic, random, and complex. Thus, one of the key safety issues is the frequent disconnections between the vehicle and the Vehicular Cloud (VC) when this vehicle is computing for a service. More important, the connection fault will disturb seriously the normal services of VCC and impact the safety works of the transportation. In this paper, a safety resource allocation mechanism is proposed against connection fault in VCC by using a modified workflow with prediction capability. We firstly propose the probability model for the vehicle movement which satisfies the high dynamics and real-time requirements of VCC. And then we propose a Prediction-based Reliability Maximization Algorithm (PRMA) to realize the safety resource allocation for VCC. The evaluation shows that our mechanism can improve the reliability and guarantee the real-time performance of the VCC.
    Type of Medium: Online Resource
    ISSN: 1574-017X , 1875-905X
    RVK:
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2016
    detail.hit.zdb_id: 2187808-0
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  • 3
    In: Evidence-Based Complementary and Alternative Medicine, Hindawi Limited, Vol. 2022 ( 2022-5-27), p. 1-10
    Abstract: Obesity is recognized as not only a major contributing factor to cardiovascular diseases but also an independent risk factor for end-stage renal disease. Previous studies have found that Huoxue Qianyang Qutan Recipe (HQQR) could reduce urinary microalbumin in patients with obesity-related hypertension (OBH). However, the renal protective activity of HQQR in OBH and its molecular targets involved remains ambiguous. In this work, we investigate the mechanism of HQQR against OBH-induced early renal damage using integrating network pharmacology and experimental validation-based strategy. First, via network pharmacology, IL-6 is identified as one of the key targets of HQQR against early renal damage in hypertension, and inhibition of inflammation is a crucial process. Second, in in vivo experiments, HQQR can lower blood pressure, lose weight, and restore metabolic abnormalities in OBH rats, which could be associated with the effects on protecting early renal damage. Finally, in the mechanism, HQQR increases SIRT1 mRNA and protein expression consistent with reduction of NF-κB acetylation and suppressed the p65-mediated inflammatory signaling pathway. As a result, HQQR robustly inhibits OBH-induced renal inflammation by reducing IL-6 mRNA and protein levels in the renal tissue and the release of IL-6 in serum of OBH rats. This study aims to provide a multimethod (network pharmacology-animal experiment) and multilevel (component-target-pathway) strategy for the prevention and treatment of OBH-induced target organ damage by traditional Chinese medicine.
    Type of Medium: Online Resource
    ISSN: 1741-4288 , 1741-427X
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2022
    detail.hit.zdb_id: 2148302-4
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  • 4
    In: Evidence-Based Complementary and Alternative Medicine, Hindawi Limited, Vol. 2022 ( 2022-3-10), p. 1-9
    Abstract: Background. This study aimed to explore the function of modified Yuejuwan (MYJ) on THP-1 macrophage-derived foam cells. Methods. First, human THP-cells were obtained, and then, grouping was made to the following: control group, foaming group, foaming group +0.2 mg/mL Jiawei Yueju pill, foaming group +0.5 mg/mL Jiawei Yueju pill, and foaming group +1 mg/mL Jiawei Yueju pill. An Oil Red O staining assay was used to examine the uptake of oxidatively modified low-density lipoprotein (oxLDL). The secretion of interleukin (IL)-1β and tumor necrosis factor (TNF)-α were determined using an enzyme-linked immunosorbent assay (ELISA). Real-time quantitative PCR (qRT-PCR) and Western blot were used to quantify genes and proteins expression levels. Results. Our results indicated that MYJ inhibited the accumulation of total cholesterol (TC), free cholesterol (FC), and cholesteryl ester (CE) in foam cells. Moreover, the secretion of IL-1β and TNF-α also downregulated in foam cells after treatment of MYJ. Furthermore, we found that tripartite motif-containing 37 (TRIM37) was significantly upregulated in foam cells. Knockdown of TRIM37 promoted cholesterol efflux and presented an anti-inflammation effect in foam cells. Furthermore, TRIM37 positively mediated the translocation of NF-κB to nuclear. It negatively regulated its ubiquitination in foam cells after interacting with TRAF2. Importantly, MYJ profoundly suppressed the function of TRIM37 in foam cells and functioned as a TRIM37 inhibitor. Conclusions. This study demonstrated that MYJ might alleviate oxLDL-induced foam cell formation by inhibiting the TRIM37/TRAF2/NF-κB pathway activity. MYJ was a potential agent in preventing atherosclerosis and indicated its potential signaling pathway in foam cells.
    Type of Medium: Online Resource
    ISSN: 1741-4288 , 1741-427X
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2022
    detail.hit.zdb_id: 2148302-4
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