In:
Canadian Journal of Chemistry, Canadian Science Publishing, Vol. 68, No. 1 ( 1990-01-01), p. 127-152
Abstract:
This paper reports several model studies that were necessary for the rational conception of a simple four-step synthesis (6 + (S)-74 → 81a–b → 83 [Formula: see text] 87 → 89) (Scheme 11) of the carbonate derivative 89 of the optically active pentacyclic dihydroxy ketoaldehyde 87, an important key intermediate for the synthesis of (+)-ryanodol (5). The optically active vinyl ketone (S)-74 that was used as starting material was prepared in four steps from d-carvone ((S)-94) (Scheme 13). The preparation of the other starting material, the o-spirolactone dienone 6, was reported in Part I. Keywords: strategy, synthesis, ryanodol, key intermediate, diterpene.
Type of Medium:
Online Resource
ISSN:
0008-4042
,
1480-3291
Language:
English
Publisher:
Canadian Science Publishing
Publication Date:
1990
detail.hit.zdb_id:
1482256-8
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