In:
Journal of Clinical Oncology, American Society of Clinical Oncology (ASCO), Vol. 30, No. 15_suppl ( 2012-05-20), p. e13094-e13094
Abstract:
e13094 Background: In the past few years, the volume of clinical trials has increased rapidly in East Asia, especially in Asian prevalent cancer types such as gastric cancer, hepatobiliary cancer. The actual degree of understanding or perceptions of clinical trials by cancer patients have been rarely studied in East Asian countries. Methods: Between July 1 st 2011 and November 30 th 2011, we conducted a prospective survey study regarding cancer patient’s awareness and willingness to participate a clinical trial. The questionnaire consisted of 21 questions based on an Index of Clinical Trial Understanding. Patients with gastrointestinal/hepatobiliary cancer who visited the Hemato-Oncology outpatient clinic at Samsung Medical Center and signed informed consent form were enrolled. The survey was conducted by a well-trained research nurse and statistical analysis was analyzed at the biostatistics core at SMC. Results: In this survey study, 1,000 patients were asked to participate and 675 patients consented to participate (67.5%). The awareness of clinical trial was substantially higher in patients with higher level of education (p 〈 .001), married (p=.004), and higher economic status (p=.001). Nevertheless, willingness to participate the clinical trial was not significantly increased by higher level of education (p=.286), married (p=.685) and higher income (p=.310). The most common source for acquisition of clinical trial was attending physicians (52.0%) followed by mass media (36.6%), other patients (6.39%), internet (3.3%) and others (1.5%). The most influential factors for patient’s willingness to participate were physician’s opinion (n=181, 26.8%), limited treatment options (n=178, 26.4%), and expectations towards new anti-cancer drug (n=142, 21.0%). Patients were likely to refuse to participate a clinical trial due to unverified treatment modality (n=320, 47.4%) and negativity for clinical trials (n=193, 28.6%). Conclusions: We surveyed a large patient cohort to specifically inquire willingness and awareness of clinical trial in Asian-prevalent cancer types. Further correlative analyses with various variable will be presented at the meeting.
Type of Medium:
Online Resource
ISSN:
0732-183X
,
1527-7755
DOI:
10.1200/jco.2012.30.15_suppl.e13094
Language:
English
Publisher:
American Society of Clinical Oncology (ASCO)
Publication Date:
2012
detail.hit.zdb_id:
2005181-5
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