In:
European Journal of Organic Chemistry, Wiley, Vol. 2011, No. 17 ( 2011-06), p. 3126-3130
Abstract:
The N ‐2,4‐dinitrophenylsulfonyl group (dinosyl, DNs) was found to be an excellent choice for the N‐activation of aziridines towards ring cleavage with primary, secondary, andsterically demanding tertiary alcohols. Alcoholysis does not need any additional catalyst and is regioselective for the less‐hindered position. No racemization in the aziridine formation or cleavage step was observed, and the resulting DNs‐sulfonamides can be deprotected quantitatively under mild conditions.
Type of Medium:
Online Resource
ISSN:
1434-193X
,
1099-0690
DOI:
10.1002/ejoc.v2011.17
DOI:
10.1002/ejoc.201100358
Language:
English
Publisher:
Wiley
Publication Date:
2011
detail.hit.zdb_id:
1410000-9
detail.hit.zdb_id:
1475010-7
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