In:
Journal of Obstetrics and Gynaecology Research, Wiley, Vol. 40, No. 4 ( 2014-04), p. 1145-1149
Abstract:
A recent report indicated that vascular endothelial growth factor ( VEGF)‐D , regulating cell proliferation and/or differentiation, may be associated with the development of placental mesenchymal dysplasia ( PMD ), a disorder characterized by cell proliferation/differentiation. In PMD placenta, we examined the expression of five cell‐proliferation/differentiation‐associated genes, namely, W nt3a, W nt5a, β‐catenin, VEGF‐D and D ickkopf‐1 ( DKK ‐1). In PMD , expressions of W nt3a, W nt5a and β‐catenin were decreased, whereas those of VEGF‐D and DKK ‐1 were increased. These abnormal expressions suggest a relationship between these genes and PMD pathogenesis/pathophysiology.
Type of Medium:
Online Resource
ISSN:
1341-8076
,
1447-0756
DOI:
10.1111/jog.2014.40.issue-4
Language:
English
Publisher:
Wiley
Publication Date:
2014
detail.hit.zdb_id:
2079101-X
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