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  • 1
    Online Resource
    Online Resource
    Medknow ; 2022
    In:  Indian Journal of Ophthalmology Vol. 70, No. 4 ( 2022), p. 1365-
    In: Indian Journal of Ophthalmology, Medknow, Vol. 70, No. 4 ( 2022), p. 1365-
    Type of Medium: Online Resource
    ISSN: 0301-4738
    Language: English
    Publisher: Medknow
    Publication Date: 2022
    detail.hit.zdb_id: 2185999-1
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  • 2
    Online Resource
    Online Resource
    IP Innovative Publication Pvt Ltd ; 2022
    In:  Indian Journal of Clinical and Experimental Ophthalmology Vol. 8, No. 1 ( 2022-3-28), p. 36-43
    In: Indian Journal of Clinical and Experimental Ophthalmology, IP Innovative Publication Pvt Ltd, Vol. 8, No. 1 ( 2022-3-28), p. 36-43
    Abstract: Immunologic corneal allograft rejection represents one of the main cause for graft failure. This study was conducted to observe and comparing the beneficial effect of topical 0.03% tacrolimus on corneal graft survival. To compare the effect of topical 0.03% tacrolimus plus 1% topical prednisolone with 1% topical prednisolone alone in preventing rejection after PK. 40 patients were randomly allocated into two groups: Group A: patients received 0.03% topical tacrolimus ointment twice daily for a month plus 1% prednisolone acetate eye drops 2 hourly and tapered monthly. Group B: patients received 1% prednisolone acetate eye drop only 2 hourly and tapered monthly. The clinical outcomes were assessed in terms of post-op complications, graft rejection, and visual acuity after 6 months of follow-up.  SPSS software, 20.0 version, IBM, Chicago were used for statistical analysis. Out of 40 patients, 29 (72.5%) were male and 11(27.5%) were female. Type of surgery and continuous suture closure was found to be statistically significant (p-value & #60; 0.05) with post-op visual acuity in both groups. Types of graft rejection were found to be statistically significant (p-value & #60; 0.05) with enucleation transplantation time(hours) in both groups and with secondary glaucoma (p = & #60;0.001) in group A. We conclude that 0.03% topical tacrolimus ointment along with 1% topical prednisolone shows promising results and can be considered as an effective modality for preventing complications like secondary glaucoma, graft rejection, and getting the better visual outcome, where p-value ( & #60;0.05) was statistically significant. All patients should be instructed with regards to the reasonable use of topical tacrolimus to avoid any side effects.
    Type of Medium: Online Resource
    ISSN: 2395-1443 , 2395-1451
    Language: Unknown
    Publisher: IP Innovative Publication Pvt Ltd
    Publication Date: 2022
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  • 3
    Online Resource
    Online Resource
    IP Innovative Publication Pvt Ltd ; 2022
    In:  Indian Journal of Clinical and Experimental Ophthalmology Vol. 8, No. 1 ( 2022-3-28), p. 51-54
    In: Indian Journal of Clinical and Experimental Ophthalmology, IP Innovative Publication Pvt Ltd, Vol. 8, No. 1 ( 2022-3-28), p. 51-54
    Abstract: : Due to the surge of post COVID mucormycosis in India there has been a significant patient load seen in hospitals we have observed that mucor is not the only culprit and there has been other fungi like aspergillus and candida, who have led to increased morbidity and mortality. : To conduct a retrospective analysis on laboratory reports of specimens sent after surgical intervention of patients admitted with mucormycosis and to identify the weightage of different fungal infections in the post COVID era. : It is a hospital based retrospective review of mycology and histopathology reports of post COVID rhino orbital mucormycosis patients referred from ophthalmology, ear nose throat surgery, oral maxillofacial surgery, neurosurgery department of mahatma gandhi memorial medical college, Indore, Madhya Pradesh from 1 June to 7 July 2021. : Out of 240 samples sent for histopathology examination, 1.6% samples showed mucormycosis with secondary aspergillosis while 98.33% samples showed primarily mucormycosis likewise 270 KOH mount reported around 8.51% mucormycosis with secondary aspergillosis, 4.81% reported primary aspergillosis, 72.15% reported primarily mucormycoses. : We acknowledge that aspergillus and candida has contributed significantly in post covid mycoses and that mucor is not the only culprit.
    Type of Medium: Online Resource
    ISSN: 2395-1443 , 2395-1451
    Language: Unknown
    Publisher: IP Innovative Publication Pvt Ltd
    Publication Date: 2022
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  • 4
    Online Resource
    Online Resource
    IP Innovative Publication Pvt Ltd ; 2022
    In:  Indian Journal of Clinical and Experimental Ophthalmology Vol. 8, No. 1 ( 2022-3-28), p. 103-108
    In: Indian Journal of Clinical and Experimental Ophthalmology, IP Innovative Publication Pvt Ltd, Vol. 8, No. 1 ( 2022-3-28), p. 103-108
    Abstract: Recurrence is a significant problem after pterygium excision. Therefore in this study its risk factors and management is discussed. This study was conducted to observe recurrence after conjunctival limbal autograft (CLAU) & to evaluate different factors related with recurrence of pterygium and assessing its different management methods. Hundred & seven patients with primary pterygium were examined, excised by CLAU and histopathology sample sent. The outcomes were assessed in terms of clinically significant recurrence till 6 months follow-up. Early topical mitomycin-C (MMC) 0.02% QID for a week was given to avoid resurgence of clinically significant pterygium, however if developed then excised by CLAU (if & #60;4mm) or AMG (Amniotic membrane grafting) (if & #62; 4mm). Out of total cases, 57% were females. Histopathology findings includeEpithelial Hyperplasia (80.4%), vascularity overwhelms fibrosis (39.1%), vascularity similar to fibrosis (28.3%), fibrosis overwhelms vascularity (34.8%), perivascular stromal inflammation (54.3%), diffuse stromal inflammation (37.0%). The following variables were significantly associated (p & #60;0.05) with the recurrence: age, redness & thickness, higher vascularity, diffuse inflammation. Factors such as younger age group, higher redness and thickness of pterygium, more vascularity, and diffuse inflammation on histopathological examination can be considered as a risk factor for recurrence. However, occupation, location, and type of pterygium were found not to be related to recurrence. Although no clinically significant recurrence was seen after mitomycin c eyedrops, but no significant correlation can be made. Young patients having pre-operative features like red and fleshy pterygium, along with vascularity more than fibrosis and diffuse inflammation on histopathological examination should be followed strictly and managed intensely.
    Type of Medium: Online Resource
    ISSN: 2395-1443 , 2395-1451
    Language: Unknown
    Publisher: IP Innovative Publication Pvt Ltd
    Publication Date: 2022
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  • 5
    Online Resource
    Online Resource
    Universidad Tecnica de Manabi ; 2022
    In:  International journal of health sciences ( 2022-04-07), p. 2661-2668
    In: International journal of health sciences, Universidad Tecnica de Manabi, ( 2022-04-07), p. 2661-2668
    Abstract: Purpose–Mucormycosis is an uncommon, rapidly progressive, commonly fatal, opportunistic serious fungal infection.The high mortality rate highlights the importance of early detection and treatment. The purpose of this study to determine theoutcome of orbital exenteration in Rhino-orbital-cerebral mucormycosis(ROCM) patients. Methods and materials–This study includesall proven ROCM patients who had underwent orbital exenteration based on SION Scoring system from 1st may 2021 to 30 june 2021 in MYH hospital, Indore.Those patients were reviewedand the outcome of orbital exenterationwas analysed. Results- Total 29ROCM patients were underwent for orbital exenteration based on SION Scoring system. 19(65.5 %)out of 29 patients had intracranial extension and 10 (34.480%) did not have intracranial extension. Out of 29, 6 (20.68%) patients hadsuccumbed to death within 10 days of orbital exenteration was having bilateral orbital involvement with intracranial extension.23(79.34%) patientshave favorable outcome with regular follow up. Conclusion- Survival of mucormycosis patients depends on the their good glycemic control,immune status, laterality of the orbital involvement and early detection of intracranial extensionof the disease.With prompt medical (high dose intravenous amphotericin B) and early aggressive surgical intervention involving FESS and orbital exenteration can preventintracranial extension and may improve survival rate .Intracranial extension of the disease has invariably been associated with high mortality.
    Type of Medium: Online Resource
    ISSN: 2550-696X , 2550-6978
    URL: Issue
    Language: Unknown
    Publisher: Universidad Tecnica de Manabi
    Publication Date: 2022
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