In:
British Journal of Psychiatry, Royal College of Psychiatrists, Vol. 201, No. 2 ( 2012-08), p. 131-136
Abstract:
Sexual dysfunction is common in psychotic disorder but it is not clear
whether it is intrinsic to the development of the illness or secondary to other factors. Aims To compare sexual function in people at ultra-high risk (UHR) of a
psychotic disorder, patients with first-episode psychosis predominantly taking antipsychotic drugs and healthy volunteers. Method Sexual function was assessed in a UHR group ( n = 31), a
group with first-episode psychosis ( n = 37) and a
matched control group of healthy volunteers ( n = 56)
using the Sexual Function Questionnaire. Results There was a significant effect of group on sexual function
( P 〈 0.001). Sexual dysfunction was evident in 50%
of the UHR group, 65% of first-episode patients and 21% of controls. Within the UHR group, sexual dysfunction was more marked in those who
subsequently developed psychosis than in those who did not. Across all groups the severity of sexual dysfunction was correlated with the
severity of psychotic symptoms ( P 〈 0.001). Within the
first-episode group there was no significant difference in sexual dysfunction between patients taking prolactin-raising v. prolactin-sparing antipsychotics. Conclusions Sexual dysfunction is present prior to onset of psychosis, suggesting it
is intrinsic to the development of illness unlikely to be related to the prolactin-raising properties of antipsychotic medication.
Type of Medium:
Online Resource
ISSN:
0007-1250
,
1472-1465
DOI:
10.1192/bjp.bp.111.101220
Language:
English
Publisher:
Royal College of Psychiatrists
Publication Date:
2012
detail.hit.zdb_id:
2021500-9
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