In:
Clinical Transplantation, Wiley, Vol. 35, No. 11 ( 2021-11)
Abstract:
Patients with a history of cardiopulmonary resuscitation (CPR) and subsequent brain death are frequently evaluated for organ donation. Whether kidneys from ≥65‐year‐old braindead donors with a history of CPR can be transplanted with satisfactory outcomes is unknown. Material & Methods All kidney transplants (KTs) from ≥65‐year‐old donors performed at our center from 1999 to 2018 ( n = 185) were retrospectively analyzed and outcome was compared for KTs from donors with and without a history of CPR ( n = 27 and n = 158, respectively). Results No significant differences in the incidence of delayed graft function (DGF) as well as 1‐ and 3‐year graft function were observed between the CPR and the no‐CPR group (DGF: 26.0% vs. 31.0%, p = .76; 1‐year serum creatinine: 150.4 μmol/L vs. 177.0 μmol/L, p = .11; 3‐year serum creatinine: 150.4 μmol/L vs. 168.2 μmol/L, p = .52, respectively). Death‐censored graft survival was comparable after 1 and 5 years (CPR group: 81.5% and 76.7% vs. no‐CPR group: 86.6% and 75.7%, p = .70). Likewise, patient survival was not significantly different. Multivariable Cox regression analysis also did not identify CPR as a significant risk factor for graft loss or death. Conclusion Our study suggests that, following stringent donor selection, the outcome of KTs from ≥65‐year‐old braindead donors with and without a history of CPR is comparable.
Type of Medium:
Online Resource
ISSN:
0902-0063
,
1399-0012
Language:
English
Publisher:
Wiley
Publication Date:
2021
detail.hit.zdb_id:
2739458-X
detail.hit.zdb_id:
2004801-4
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