In:
Influenza and Other Respiratory Viruses, Wiley, Vol. 10, No. 4 ( 2016-07), p. 247-253
Abstract:
A dramatic increase of influenza activity in Russia since week 3 of 2016 significantly differs from previous seasons in terms of the incidence of influenza and acute respiratory infection ( ARI ) and in number of lethal cases. We performed antigenic analysis of 108 and whole‐genome sequencing of 77 influenza A(H1N1)pdm09 viruses from Moscow and Saint Petersburg. Most of the viruses were antigenically related to the vaccine strain. Whole‐genome analysis revealed a composition of specific mutations in the internal genes (D2E and M83I in NEP , E125D in NS 1, M105T in NP , Q208K in M1, and N204S in PA ‐X) that probably emerged before the beginning of 2015/2016 epidemic season.
Type of Medium:
Online Resource
ISSN:
1750-2640
,
1750-2659
DOI:
10.1111/irv.2016.10.issue-4
Language:
English
Publisher:
Wiley
Publication Date:
2016
detail.hit.zdb_id:
2272349-3
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