In:
Journal of Movement Disorders, The Korean Movement Disorder Society, Vol. 14, No. 3 ( 2021-09-30), p. 221-225
Kurzfassung:
Objective To assess nocturnal hypokinesia using the Korean version of the Nocturnal Hypokinesia Questionnaire (NHQ-K) in Parkinson’s disease (PD) patients across disease stages.Methods We developed the NHQ-K and performed questionnaire-based interviews with 108 PD patients from three referral hospitals. Clinical associations of nocturnal hypokinesia and its impact on health-related quality of life (HRQoL) were also analyzed.Results The NHQ-K showed acceptable internal consistency (0.83) and interrater reliability (0.95). Nocturnal hypokinesia significantly affected HRQoL in PD patients at both the early and advanced stages (adjusted p 〈 0.001). Increased severity of nocturnal hypokinesia was associated with dyskinesias, off-period disability, apathy, and anxious mood in PD patients (adjusted p 〈 0.01) after controlling for disease severity and medication dose.Conclusion The NHQ-K is useful for screening nocturnal hypokinesia in PD patients. Given the high impact of nocturnal hypokinesia on HRQoL, comprehensive management of nocturnal disability is needed for PD patients.
Materialart:
Online-Ressource
ISSN:
2005-940X
,
2093-4939
Sprache:
Englisch
Verlag:
The Korean Movement Disorder Society
Publikationsdatum:
2021
ZDB Id:
3021788-X
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