In:
Chemistry & Biodiversity, Wiley, Vol. 20, No. 9 ( 2023-09)
Kurzfassung:
A phytochemical investigation of the methanolic extract of the Macropanax membranifolius C.B. Shang leaves led to the isolation of three new flavans, (2 R ,3 R )‐4′ ‐O‐ methylcatechin 5 ‐O‐β‐ D‐glucopyranoside ( 1 ), (2 S ,3 S )‐4′ ‐O‐ methylcatechin 5 ‐O‐β‐ D‐glucopyranoside ( 2 ), (2 S ,3 R )‐4′ ‐O‐ methylcatechin 5 ‐O‐β‐ D‐glucopyranoside ( 3 ), one new triterpene glycoside 3 ‐O‐β‐ D‐xylopyranosyl‐(1→6)‐[ β ‐D‐xylopyranosyl‐(1→2)] ‐β‐ D‐glucopyranosyl‐oleanolic acid 28 ‐O‐β‐ D‐glucopyranoside ( 4 ), together with nine known compounds ( 5 ‐ 13 ). Their chemical structures were elucidated based on HR‐ESI‐MS, NMR spectroscopic data. The absolute configurations of compounds 1 – 3 were established by electronic circular dichroism (ECD) spectra. At concentration of 20 μM, compounds 1 – 13 showed the percentages of dead cell in the range of 2.14 % to 33.61 % against KB, HepG2, HL60, P388, HT29, and MCF7 cancerous cell lines by SRB assay.
Materialart:
Online-Ressource
ISSN:
1612-1872
,
1612-1880
DOI:
10.1002/cbdv.202301090
Sprache:
Englisch
Verlag:
Wiley
Publikationsdatum:
2023
ZDB Id:
2139001-0
SSG:
12
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