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  • 1
    In: Cureus, Springer Science and Business Media LLC
    Type of Medium: Online Resource
    ISSN: 2168-8184
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
    detail.hit.zdb_id: 2747273-5
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  • 2
    Online Resource
    Online Resource
    Nepal Journals Online (JOL) ; 2021
    In:  Journal of Patan Academy of Health Sciences Vol. 8, No. 3 ( 2021-12-31), p. 23-29
    In: Journal of Patan Academy of Health Sciences, Nepal Journals Online (JOL), Vol. 8, No. 3 ( 2021-12-31), p. 23-29
    Abstract: Introduction: Corona virus disease 2019(COVID-19) is an infectious disease caused by newly discovered coronavirus SARS CoV-2 (Severe acute respiratory syndrome coronavirus 2). Majority of the COVID-19 infections have mild symptoms in general populations but symptoms may be more severe in immunocompromised and elderly patients and may be in CML populations also. We expected most of CML patients in elderly age group may develop severe symptoms of COVID-19 and its severity may vary in different phases of the CML and different types of TKI being used. Method: From January 2020 to June 2021 all adult CML patients receiving treatment from Patan Hospital, identified with SARS Cov-2 infection were included in the study. Those patients who had final outcome from COVID-19 infection was taken. Result: The prevalence of SARS CoV-2 infection in CML population in our hospital is 2.60%. The COVID-19 infection was seen more on female population and younger age group less then 60 years old. Even though the infection rate was higher in the younger age group and infection rate was lesser in CML-CP group, mortality was higher in elderly and advances age group which was statically significant. Regardless of their symptoms, stages, severity of the symptoms, different TKI being used about 92% have fully recovered from COVID-19 infection. Conclusion: About 92% of CML patients had fully recovered from COVID-19 infection. In our study advanced stage and elderly age group were associated with more severity of the disease and higher mortality rate.
    Type of Medium: Online Resource
    ISSN: 2091-2757 , 2091-2749
    Language: Unknown
    Publisher: Nepal Journals Online (JOL)
    Publication Date: 2021
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  • 3
    Online Resource
    Online Resource
    Nepal Journals Online (JOL) ; 2016
    In:  Journal of Patan Academy of Health Sciences Vol. 3, No. 2 ( 2016-12-01), p. 10-14
    In: Journal of Patan Academy of Health Sciences, Nepal Journals Online (JOL), Vol. 3, No. 2 ( 2016-12-01), p. 10-14
    Abstract: Introductions: Classifying morphological pattern of renal involvement is important in systemic lupus erythematosus (SLE) for definitive treatment and prognosis. This study aims to analyse the histopathological pattern of glomerula in SLE patients.Methods: This was a retrospective chart review of patients diagnosed with SLE who had renal biopsy during October 2013 to September 2015 at Patan Hospital.Results: There were 38 patients of SLE. Antinuclear antibody (ANA) was positive in all 38 (100 %), Anti-dsDNA seen in 18 (47.4%). Active urinary sediment & proteinuria was seen in 25 (65.8%) patients and proteinuria in 13 (34.2%) patients. Histopathological patterns were of glomerular involvement, ISN Class II in 2 (5.3%), Class III in 2 (5.3%), class IV in 20 (52.5%), Class V in 6 (15.8%) and mixed IV-V in 8 (21.1%).Conclusions: The diffuse proliferative lupus nephritis (ISN Class IV) was the most common pattern of lupus nephritis encountered in our study followed by mixed pattern (ISN Class IV & V) and membranous lupus nephritis (ISN class IV). Journal of Patan Academy of Health Sciences. 2016 Dec;3(2):10-14
    Type of Medium: Online Resource
    ISSN: 2091-2757 , 2091-2749
    Language: Unknown
    Publisher: Nepal Journals Online (JOL)
    Publication Date: 2016
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