In:
Clinical and Experimental Pharmacology and Physiology, Wiley, Vol. 45, No. 8 ( 2018-08), p. 866-869
Kurzfassung:
The role of serum uric acid ( SUA ) in cardiovascular risk prediction remains to be further determined. We assessed the predictive value of SUA for the incidence of coronary artery disease ( CAD ) in 2287 essential hypertensive patients who were followed up for a mean period of 8 years. The distribution of SUA levels at baseline was split by the median (5.2 mg/ dL ) and subjects were classified into those with high and low values. Hypertensives who developed CAD (n = 57) compared to those without CAD at follow‐up (n = 2230) had at baseline higher SUA . In multivariate Cox regression model, among established confounders, high SUA (hazard ratio = 1.216, P = .016) turned out to be independent predictor of CAD . In essential hypertensive patients SUA independently predicts CAD .
Materialart:
Online-Ressource
ISSN:
0305-1870
,
1440-1681
DOI:
10.1111/cep.2018.45.issue-8
DOI:
10.1111/1440-1681.12928
Sprache:
Englisch
Verlag:
Wiley
Publikationsdatum:
2018
ZDB Id:
2020033-X
SSG:
15,3
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