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  • Wiley  (4)
  • Jiang, H.  (4)
  • Liu, H.  (4)
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  • Wiley  (4)
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  • 1
    Online Resource
    Online Resource
    Analysis of brain activity involved in chewing‐side preference during chewing: an fMRI study
    Wiley ; 2015
    In:  Journal of Oral Rehabilitation Vol. 42, No. 1 ( 2015-01), p. 27-33
    Details
    In: Journal of Oral Rehabilitation, Wiley, Vol. 42, No. 1 ( 2015-01), p. 27-33
    Abstract: The aim of this study was to investigate the activation characteristics of cerebral cortex in participants with CSP during rhythmic chewing movement. Sixteen right‐handed participants with left (two males: 29·0 ± 8·4 years old, six females: 32·3 ± 4·8 years old) or right (four males: 31·0 ± 6·1 years old, four females: 30·8 ± 4·7 years old) CSP were scanned by functional magnetic resonance imaging during rhythmic chewing. The on‐off sequence of scanning was 30 s of rhythmic chewing and 30 s of rest (off) a total of five times. The results showed that blood oxygen level‐dependent signals in the contralateral (to the CSP ) primary sensorimotor cortex increased more than in the ipsilateral primary sensorimotor cortex in participants with both left and right CSP ( P  ≤ 0·001). Moreover, the BOLD signal within the right substantia nigra of midbrain, brainstem was more significantly ( P  ≤ 0·001) activated than its left counterpart in participants with left CSP , while no activation was observed in those with right CSP . The similar activation of the cerebellum was in participants with right CSP . The inferior parietal lobule, inferior frontal gyrus and left insular cortex were significantly ( P  ≤ 0·001) activated in participants with CSP . These findings suggest a relationship between hemispheric dominance and CSP in the primary sensorimotor cortex responsible for rhythmic chewing movement. The brainstem and the cerebellum might also play important role in the regulation of CSP . Furthermore, the IFG , IPL and insular may contribute to higher cognitive information processing for participants with CSP .
    Type of Medium: Online Resource
    ISSN: 0305-182X , 1365-2842
    URL: Issue
    URL: Article
    DOI: 10.1111/joor.2014.42.issue-1
    DOI: 10.1111/joor.12224
    Language: English
    Publisher: Wiley
    Publication Date: 2015
    detail.hit.zdb_id: 2007587-X
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    Online Resource
  • 2
    Online Resource
    Online Resource
    The biological effects of occlusal trauma on the stomatognathic system - a focus on animal studies
    Wiley ; 2013
    In:  Journal of Oral Rehabilitation Vol. 40, No. 2 ( 2013-02), p. 130-138
    Details
    In: Journal of Oral Rehabilitation, Wiley, Vol. 40, No. 2 ( 2013-02), p. 130-138
    Type of Medium: Online Resource
    ISSN: 0305-182X
    URL: Article
    DOI: 10.1111/joor.12017
    Language: English
    Publisher: Wiley
    Publication Date: 2013
    detail.hit.zdb_id: 2007587-X
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  • 3
    Online Resource
    Online Resource
    Assessment of osseous morphology of temporomandibular joint in asymptomatic participants with chewing‐side preference
    Wiley ; 2015
    In:  Journal of Oral Rehabilitation Vol. 42, No. 2 ( 2015-02), p. 105-112
    Details
    In: Journal of Oral Rehabilitation, Wiley, Vol. 42, No. 2 ( 2015-02), p. 105-112
    Abstract: Chewing‐side preference ( CSP ) may be associated with temporomandibular disorders. However, little information exists regarding whether CSP will lead to osseous changes of temporomandibular joint ( TMJ ) in asymptomatic participants. The aim of this study was to investigate the relationship between osseous morphology of TMJ in asymptomatic participants with CSP and without CSP . Of the 121 healthy dentate participants, 35 participants with left CSP , 38 with right CSP and other 48 without CSP were scanned by cone‐beam computed tomography. The dimensions of the reconstructed images of opposing TMJ s were compared. Statistical analyses were performed using spss 16.0 software. The results showed that there were no significant differences between the dimensions of bilateral structures of the TMJ ( P 1  〉  0·05) in participants without CSP . However, the posterior–superior, posterior and lateral joint space of the preferred side were smaller than that of the unpreferred side in participants with CSP ( P 2  〈  0·01) and bilateral TMJ in participants without CSP ( P 3  〈  0·01). In addition, width of condylar neck of the unpreferred side both in sagittal and perpendicular to the long axis of condyle views was greater than that of the preferred side in participants with CSP ( P 2  〈  0·01) and bilateral TMJ of participants without CSP ( P 4  〈  0·01). Also, the inclination of articular eminence of the preferred side in view perpendicular to the long axis of condyle was less than that of the unpreferred side ( P 2  〈  0·05). These findings suggest CSP affects osseous morphology of TMJ in asymptomatic participants.
    Type of Medium: Online Resource
    ISSN: 0305-182X , 1365-2842
    URL: Issue
    URL: Article
    DOI: 10.1111/joor.2015.42.issue-2
    DOI: 10.1111/joor.12240
    Language: English
    Publisher: Wiley
    Publication Date: 2015
    detail.hit.zdb_id: 2007587-X
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  • 4
    Online Resource
    Online Resource
    Increased levels of IL ‐21 responses are associated with the severity of liver injury in patients with chronic active hepatitis B
    Wiley ; 2014
    In:  Journal of Viral Hepatitis Vol. 21, No. 9 ( 2014-09)
    Details
    In: Journal of Viral Hepatitis, Wiley, Vol. 21, No. 9 ( 2014-09)
    Abstract: Interleukin‐21 ( IL ‐21) participates in tissue damage in various immune‐mediated diseases. Its role in the pathogenesis of chronic active hepatitis B ( CAHB ) has not been clarified. The frequency of circulating IL ‐21 + T cells and the levels of serum and intrahepatic IL ‐21 have been characterized in 70 CAHB patients, 32 inactive carrier ( IC ), 18 chronic hepatitis C ( CHC ) and 20 healthy controls ( HC ). Their potential association with liver injury was analysed. The percentages of IL ‐21 + CD 3 + CD 8 − and IL ‐21 + CD 3 + CD 8 + T cells and the levels of serum IL ‐21 in CAHB patients were significantly higher than that in the IC , CHC patients and HC ( P   〈  0.001) and were correlated positively with the levels of serum alanine aminotransferase ( ALT , r  = 0.424, P   〈  0.001; r  = 0.392, P  = 0.001) and aspartate aminotransferase ( AST , r  = 0.388, P  = 0.001; r  = 0.329, P  = 0.005) in CAHB patients, respectively. The levels of IL ‐21 expression in the liver tissues were associated significantly with increased degrees of inflammation and fibrosis in CAHB patients ( P   〈  0.01 or P   〈  0.05). Our findings suggest that aberrant IL ‐21 responses may be associated with the progression of CHB .
    Type of Medium: Online Resource
    ISSN: 1352-0504 , 1365-2893
    URL: Issue
    URL: Article
    DOI: 10.1111/jvh.2014.21.issue-9
    DOI: 10.1111/jvh.12242
    Language: English
    Publisher: Wiley
    Publication Date: 2014
    detail.hit.zdb_id: 2007924-2
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