In:
Advanced Synthesis & Catalysis, Wiley, Vol. 359, No. 24 ( 2017-12-19), p. 4332-4339
Abstract:
A novel three‐component selenosulfonation of 1,7‐enynes with sulfinic acids and diphenyl diselenides for the formation of multifunctional 3,4‐dihydroquinolin‐2(1 H )‐ones was developed in batch and flow. This room‐temperature protocol provides a highly efficient approach to diverse selenosulfones in moderate to excellent yields and with a broad scope of substrates. It should provide a potential synthesis method for the construction of diverse and meaningful 3,4‐dihydroquinolin‐2(1 H )‐ones derivatives in the fields of pharmaceutical and biological chemistry. Additionally, an obvious acceleration (20 h to 43 s) was obtained under micro flow conditions. magnified image
Type of Medium:
Online Resource
ISSN:
1615-4150
,
1615-4169
DOI:
10.1002/adsc.v359.24
DOI:
10.1002/adsc.201701118
Language:
English
Publisher:
Wiley
Publication Date:
2017
detail.hit.zdb_id:
2041384-1
detail.hit.zdb_id:
2033084-4
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