In:
Dementia and Geriatric Cognitive Disorders, S. Karger AG, Vol. 37, No. 5-6 ( 2014), p. 347-356
Abstract:
〈 b 〉 〈 i 〉 Background: 〈 /i 〉 〈 /b 〉 Although the Mini-Mental Status Examination (MMSE) is the most widely used screening instrument for dementia, it has several limitations. 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 We developed and validated a new scoring method of the MMSE, namely the short form of the MMSE (MMSE-S). 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 The MMSE-S was more robust to demographic influences than the MMSE. The influence of education, in particular, was smaller in the MMSE-S compared to the MMSE (p 〈 0.01). The diagnostic accuracy of the MMSE-S for very mild to mild dementia was also better than that of the original MMSE (p 〈 0.0001). Its specificity, in particular, was higher than that of the original MMSE. In Korea, we could improve the post-test probability for dementia from 46.88 to 64.76% by employing the MMSE-S instead of the MMSE. We also provided optimal cut-off scores for dementia stratified by age, education, and gender, which may further improve the diagnostic accuracy of the MMSE-S for dementia. 〈 b 〉 〈 i 〉 Conclusion: 〈 /i 〉 〈 /b 〉 Due to its good accuracy and brevity, the MMSE-S may contribute to enhancing the cost-effectiveness of and accessibility to dementia screening as well as early diagnosis and treatment of dementia, particularly in low- and middle-income countries.
Type of Medium:
Online Resource
ISSN:
1420-8008
,
1421-9824
Language:
English
Publisher:
S. Karger AG
Publication Date:
2014
detail.hit.zdb_id:
1482186-2
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