GLORIA

GEOMAR Library Ocean Research Information Access

X

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Isomoto, H  (6)
  • 2000-2004  (6)
Material
Publisher
Person/Organisation
Language
Years
  • 2000-2004  (6)
Year
  • 1
    Online Resource
    Online Resource
    Comparison of the Microbicidal Activities of Superoxidized and Ozonated Water in the Disinfection of Endoscopes
    SAGE Publications ; 2003
    In:  Journal of International Medical Research Vol. 31, No. 4 ( 2003-08), p. 299-306
    Details
    In: Journal of International Medical Research, SAGE Publications, Vol. 31, No. 4 ( 2003-08), p. 299-306
    Abstract: The microbicidal activities of super-oxidized water (electrolysed strong acid water [ESAW] or electrolysed weak acid water [EWAW] ), ozonated water, 0.05% chlorhexidine and 2% glutaraldehyde were tested against seven strains of clinical micro-organism isolates. Following incubation of bacterial suspensions in ESAW and EWAW for 10 s, the number of micro-organisms was reduced below the detection limit. The microbicidal activities of ESAW and EWAW were similar to that of glutaraldehyde, and superior to ozonated water and 0.05% chlorhexidine. The microbicidal activities of ESAW, EWAW and ozonated water were markedly diminished in the presence of albumin. Microbial contamination of upper gastrointestinal endoscopes was detected after 90 endoscopic procedures, but treatment of the endoscope with ESAW, EWAW or ozonated water eradicated the microbes. These results indicate that ESAW and EWAW are effective disinfectants after mechanical cleaning of upper gastrointestinal endoscopes, and can, therefore, be used in the endoscopy unit.
    Type of Medium: Online Resource
    ISSN: 0300-0605 , 1473-2300
    URL: Article
    DOI: 10.1177/147323000303100407
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2003
    detail.hit.zdb_id: 2082422-1
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 2
    Online Resource
    Online Resource
    Impact of CagA Status on Serum Gastrin and Pepsinogen I and II Concentrations in Japanese Children with Helicobacter Pylori Infection
    SAGE Publications ; 2003
    In:  Journal of International Medical Research Vol. 31, No. 4 ( 2003-08), p. 247-252
    Details
    In: Journal of International Medical Research, SAGE Publications, Vol. 31, No. 4 ( 2003-08), p. 247-252
    Abstract: The study aimed to determine the association between cytotoxin-associated gene product (CagA), serum gastrin and pepsinogen levels in Japanese children infected with Helicobacter pylori. Three hundred children were enrolled in the study. H. pylori infection was assessed using an enzyme-linked immunosorbent assay, and CagA status was assessed using immunoblotting. Serum gastrin and pepsinogen concentrations were measured by radioimmunoassay. H. pylori seroprevalence was 12.3% (37/300) and CagA status was identified in 28/37 H. pylori-seropositive children (75.7%). Serum pepsinogen I and II levels were significantly higher in CagA-seropositive than CagA-seronegative children with H. pylori infection. There was no significant relationship between CagA seropositivity and serum gastrin levels. In conclusion, CagA status has a significant impact on serum pepsinogen levels, possibly through enhanced gastric mucosal inflammation.
    Type of Medium: Online Resource
    ISSN: 0300-0605 , 1473-2300
    URL: Article
    DOI: 10.1177/147323000303100401
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2003
    detail.hit.zdb_id: 2082422-1
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 3
    Online Resource
    Online Resource
    Polymorphism of CYP2C19 and Gastric Emptying in Patients with Proton Pump Inhibitor-Resistant Gastric Ulcers
    SAGE Publications ; 2002
    In:  Journal of International Medical Research Vol. 30, No. 4 ( 2002-08), p. 413-421
    Details
    In: Journal of International Medical Research, SAGE Publications, Vol. 30, No. 4 ( 2002-08), p. 413-421
    Abstract: The aim of the present study was to investigate whether CYP2C19 polymorphism status and gastric emptying are related to healing in patients with gastric ulcers. We studied the CYP2C19 status in seven patients with proton pump inhibitor (PPI)-resistant ulcers, 21 with PPI-sensitive ulcers and 46 healthy volunteers using polymerase chain reaction restriction fragment length polymorphism to detect CYP2C19m1 mutation in exon 5 and CYP2C19m2 mutation in exon 4. Gastric emptying was evaluated using the 13 C-acetate breath test. The frequency of phenotypes, indicated by genotypes, did not differ significantly between the three patient groups. The peak time of 13 C excretion in patients with PPI-resistant ulcers was significantly longer than that of patients with PPI-sensitive ulcers and healthy volunteers. Our results suggest that rate of gastric emptying, but not CYP2C19 polymorphism, is likely to be an important factor in the delayed healing of patients with PPI-resistant gastric ulcer.
    Type of Medium: Online Resource
    ISSN: 0300-0605 , 1473-2300
    URL: Article
    DOI: 10.1177/147323000203000408
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2002
    detail.hit.zdb_id: 2082422-1
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 4
    Online Resource
    Online Resource
    Effect of Intrarectal Prostaglandin E 2 Analogue (Enprostil) on Trinitrobenzenesulphonic Acid-Induced Colitis in Rats
    SAGE Publications ; 2000
    In:  Journal of International Medical Research Vol. 28, No. 1 ( 2000-02), p. 28-35
    Details
    In: Journal of International Medical Research, SAGE Publications, Vol. 28, No. 1 ( 2000-02), p. 28-35
    Abstract: Prostaglandins exert a protective effect on colonic mucosa in experimentally induced colitis. This study investigated the effect of enprostil, a prostaglandin E 2 (PGE 2 ) analogue, on trinitrobenzenesulphonic acid (TNBS)-induced colitis in rats. Each rat received a rectal enema containing TNBS (30 mg), followed 24 h later by intrarectal once-daily enprostil (200 μg). Enprostil-treated and control rats were killed on day 3 (enprostil group, n = 5; control, n = 6) or day 10 (enprostil group, n = 5; control, n = 5) after TNBS treatment. The area of damaged mucosa of the colon was measured relative to the total colonic area. We also determined the macroscopic score of mucosal damage, and measured PGE 2 , 6-ketoprostaglandin F 1α (6-keto-PGF 1α ) and thromboxane B 2 (TXB 2 ) concentration in portal vein blood samples. Enprostil significantly reduced both the area of damaged mucosa (including the ulcer area) and the macroscopic score after 3 days' treatment compared with control. Similarly, enprostil significantly reduced plasma concentration of PGE 2 , 6-keto-PGF 1α and TXB 2 during the acute phase at day 3 of treatment compared with control, but not at day 10. These results suggest that PGE 2 enema may have therapeutic potential for treating patients with proctitis or left-sided colitis.
    Type of Medium: Online Resource
    ISSN: 0300-0605 , 1473-2300
    URL: Article
    DOI: 10.1177/147323000002800105
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2000
    detail.hit.zdb_id: 2082422-1
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 5
    Online Resource
    Online Resource
    Expression of Interleukin 6 and Its Receptor in Human Gastric and Colorectal Cancers
    SAGE Publications ; 2003
    In:  Journal of International Medical Research Vol. 31, No. 2 ( 2003-04), p. 69-75
    Details
    In: Journal of International Medical Research, SAGE Publications, Vol. 31, No. 2 ( 2003-04), p. 69-75
    Abstract: Interleukin 6 (IL-6) is a pleiotropic cytokine with many physiological functions. The present study was designed to determine the expression of IL-6 and its receptor (IL-6R) in human gastric and colorectal cancers. Nine gastric- and nine colorectal cancer cell lines were analysed. The IL-6 gene was expressed in two gastric cancer cell lines and one colorectal cancer cell line; however, most of the cancer cell lines studied expressed the IL-6R gene. The level of IL-6 secretion in the gastric cancer cell lines correlated with the level of soluble IL-6R secretion, and was significantly higher ( 〉 ~100 pg/ml) than the level of IL-6 secretion in the colorectal cancer cell lines ( 〉 ~50 pg/ml). These results suggest that IL-6 may act in a paracrine fashion rather than an autocrine fashion in these cell lines.
    Type of Medium: Online Resource
    ISSN: 0300-0605 , 1473-2300
    URL: Article
    DOI: 10.1177/147323000303100202
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2003
    detail.hit.zdb_id: 2082422-1
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 6
    Online Resource
    Online Resource
    Micronutrient Status and Glutathione Peroxidase in Bedridden Patients on Tube Feeding
    SAGE Publications ; 2001
    In:  Journal of International Medical Research Vol. 29, No. 3 ( 2001-06), p. 181-188
    Details
    In: Journal of International Medical Research, SAGE Publications, Vol. 29, No. 3 ( 2001-06), p. 181-188
    Abstract: Deficiency of micronutrients, especially selenium, is common in critically ill patients. We investigated the micronutrient status (selenium, zinc, copper and manganese) and glutathione peroxidase (GSH-Px) activity in 30 tube-fed patients and 21 hospitalized non-tube-fed control patients. Serum levels of selenium, copper and manganese in tube-fed patients were significantly lower than in control patients (selenium: 4.85 ± 1.38 μg/dl versus 8.67 ± 1.45 μg/dl; copper: 44.7 ± 36.9 μg/dl versus 92.1 ± 21.2 μg/dl; manganese 0.59 ± 0.41 μg/dl versus 1.52 ± 0.59 μg/dl). However, zinc and log GSH-Px in the serum were similar in the two groups. Serum selenium concentration correlated with the daily intake of selenium in tube-fed patients, but zinc, copper and manganese concentrations did not correlate with the daily intake of the respective trace elements in tube-fed patients. Blood GSH-Px activity correlated positively with serum selenium concentrations in the control patients, but not in tube-fed patients. These results demonstrate that selenium content of enteral feed appears to be insufficient to maintain normal serum levels in elderly bedridden patients. Our findings emphasize the importance of monitoring micronutrient status in patients on enteral feeding to avoid trace element deficiencies
    Type of Medium: Online Resource
    ISSN: 0300-0605 , 1473-2300
    URL: Article
    DOI: 10.1177/147323000102900305
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2001
    detail.hit.zdb_id: 2082422-1
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...