In:
Acta Endocrinologica, Oxford University Press (OUP), Vol. 81, No. 1 ( 1976-01), p. 19-27
Abstract:
Immunoreactive plasma human prolactin (HPr) and human growth hormone (HGH) concentrations were measured in six normal young men with polygraphic sleep monitoring during normal sleep and during sleep in which 1-dihydroxyphenylalanine (1-DOPA) was infused intravenously at a rate of 0.8 to 1.0 mg/min. The intravenous infusion of 1-DOPA significantly suppressed the episodic release of HPr during sleep and the occurrence of rapid eye movement (REM) sleep. However, HGH release during sleep was not remarkably influenced by 1-DOPA. These results suggest that central catecholaminergic neural mechanisms are related to both sleep-related HPr release and REM sleep, but do not play an important role in sleep-related HGH release.
Type of Medium:
Online Resource
ISSN:
0804-4643
,
1479-683X
DOI:
10.1530/acta.0.0810019
Language:
Unknown
Publisher:
Oxford University Press (OUP)
Publication Date:
1976
detail.hit.zdb_id:
1485160-X
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