In:
PLOS ONE, Public Library of Science (PLoS), Vol. 16, No. 11 ( 2021-11-9), p. e0259701-
Abstract:
Peripancreatic fluid collections have been observed in most patients with postoperative pancreatic fistula after distal pancreatectomy; however, optimal management remains unclear. This study aimed to evaluate the management and outcomes of patients with postoperative pancreatic fistula and verify the significance of computed tomography values for predicting peripancreatic fluid infections after distal pancreatectomy. We retrospectively investigated 259 consecutive patients who underwent distal pancreatectomy. Grade B postoperative pancreatic fistula patients were divided into two subgroups (B-antibiotics group and B-intervention group) and outcomes were compared. Predictive factor analysis of peripancreatic fluid infection was performed. Clinically relevant postoperative pancreatic fistulas developed in 88 (34.0%) patients. The duration of hospitalization was significantly longer in the B-intervention (n = 54) group than in the B-antibiotics group (n = 31; 41 vs. 17 days, p 〈 0.001). Computed tomography values of the infected peripancreatic fluid collections were significantly higher than those of the non-infected peripancreatic fluid collections (26.3 vs. 16.1 Hounsfield units, respectively; p 〈 0.001). The outcomes of the patients with grade B postoperative pancreatic fistulas who received therapeutic antibiotics only were considerably better than those who underwent interventions. Computed tomography values may be useful in predicting peripancreatic fluid collection infection after distal pancreatectomy.
Type of Medium:
Online Resource
ISSN:
1932-6203
DOI:
10.1371/journal.pone.0259701
DOI:
10.1371/journal.pone.0259701.g001
DOI:
10.1371/journal.pone.0259701.g002
DOI:
10.1371/journal.pone.0259701.g003
DOI:
10.1371/journal.pone.0259701.t001
DOI:
10.1371/journal.pone.0259701.t002
DOI:
10.1371/journal.pone.0259701.t003
DOI:
10.1371/journal.pone.0259701.t004
DOI:
10.1371/journal.pone.0259701.t005
DOI:
10.1371/journal.pone.0259701.s001
DOI:
10.1371/journal.pone.0259701.s002
DOI:
10.1371/journal.pone.0259701.s003
DOI:
10.1371/journal.pone.0259701.s004
DOI:
10.1371/journal.pone.0259701.r001
DOI:
10.1371/journal.pone.0259701.r002
DOI:
10.1371/journal.pone.0259701.r003
DOI:
10.1371/journal.pone.0259701.r004
Language:
English
Publisher:
Public Library of Science (PLoS)
Publication Date:
2021
detail.hit.zdb_id:
2267670-3
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