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  • Huang, Xuhua  (2)
  • Chemistry/Pharmacy  (2)
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  • Chemistry/Pharmacy  (2)
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  • 1
    In: Journal of Separation Science, Wiley, Vol. 43, No. 5 ( 2020-03), p. 865-876
    Abstract: We investigated crude Aster tataricus , vinegar‐processed Aster tataricus , honey‐processed Aster tataricus , and steamed Aster tataricus as a case study and developed a comprehensive strategy integrating quantitative analysis and chemical pattern recognition methods for the evaluation and differentiation of Aster tataricus from different regions, as well as related processed products. In the study, 15 batches of raw Aster tataricus collected from seven provinces were analyzed. A sensitive and rapid ultra‐high performance liquid chromatography with tandem mass spectrometry method for simultaneous determination of 15 compounds was established to evaluate the quality of raw and processed Aster tataricus . Furthermore, multivariate statistical techniques were applied to compare the differences among Aster tataricus samples. As a result, the herbs collected from seven provinces were divided into two categories, and chlorogenic acid was the most important component distinguishing between the regions. Moreover, all of the raw and processed samples were classified by partial least squares discriminant analysis based on the 15 analyzed compounds. Results showed that raw Aster tataricus , vinegar‐processed Aster tataricus , honey‐processed Aster tataricus , and steamed Aster tataricus were clustered in four different areas. Shionone, chlorogenic acid and kaempferol were the significant constituents differentiating the raw and differently processed Aster tataricus samples.
    Type of Medium: Online Resource
    ISSN: 1615-9306 , 1615-9314
    URL: Issue
    RVK:
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2047990-6
    Location Call Number Limitation Availability
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  • 2
    In: Journal of Separation Science, Wiley, Vol. 44, No. 20 ( 2021-10), p. 3883-3897
    Abstract: Aster tataricus , a traditional Chinese herb, has been used to treat cough and asthma for many years. Its raw and processed products have different pharmacological effects in clinical applications. To explore the chemical profile differences of components in A. tataricus processed with different methods, metabolomics methods based on ultra‐high‐performance liquid chromatography coupled with quadrupole time of flight mass spectrometry and gas chromatography–mass spectrometry were developed. Chemometrics strategy was applied to filter and screen the candidate compounds. The accuracy of differential markers was validated by back propagation neural network. The established methods showed that raw A. tataricus , honey‐processed A. tataricus , vinegar‐processed A. tataricus , and steamed A. tataricus were clearly divided into four groups, suggesting that the components were closely related to the processing methods. A total of 64 nonvolatile and 43 volatile compounds were identified in A. tataricus , and 22 nonvolatile and 12 volatile differential constituents were selected to distinguish the raw and processed A. tataricus . This study demonstrated that the metabolomics methods coupled with chemometrics were a comprehensive strategy to analyze the chemical profile differences and provided a reliable reference for quality evaluation of A. tataricus .
    Type of Medium: Online Resource
    ISSN: 1615-9306 , 1615-9314
    URL: Issue
    RVK:
    Language: English
    Publisher: Wiley
    Publication Date: 2021
    detail.hit.zdb_id: 2047990-6
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
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