In:
Journal of Separation Science, Wiley, Vol. 44, No. 20 ( 2021-10), p. 3883-3897
Abstract:
Aster tataricus , a traditional Chinese herb, has been used to treat cough and asthma for many years. Its raw and processed products have different pharmacological effects in clinical applications. To explore the chemical profile differences of components in A. tataricus processed with different methods, metabolomics methods based on ultra‐high‐performance liquid chromatography coupled with quadrupole time of flight mass spectrometry and gas chromatography–mass spectrometry were developed. Chemometrics strategy was applied to filter and screen the candidate compounds. The accuracy of differential markers was validated by back propagation neural network. The established methods showed that raw A. tataricus , honey‐processed A. tataricus , vinegar‐processed A. tataricus , and steamed A. tataricus were clearly divided into four groups, suggesting that the components were closely related to the processing methods. A total of 64 nonvolatile and 43 volatile compounds were identified in A. tataricus , and 22 nonvolatile and 12 volatile differential constituents were selected to distinguish the raw and processed A. tataricus . This study demonstrated that the metabolomics methods coupled with chemometrics were a comprehensive strategy to analyze the chemical profile differences and provided a reliable reference for quality evaluation of A. tataricus .
Type of Medium:
Online Resource
ISSN:
1615-9306
,
1615-9314
DOI:
10.1002/jssc.202100315
Language:
English
Publisher:
Wiley
Publication Date:
2021
detail.hit.zdb_id:
2047990-6
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