In:
BMJ Open, BMJ, Vol. 9, No. 6 ( 2019-06), p. e028966-
Abstract:
The aim of this study was to assess the factors associated with disease-specific quality of life in Taiwanese patients with ankylosing spondylitis. Design A cross-sectional study. Setting A regional teaching hospital in southern Taiwan. Participants Adult patients with ankylosing spondylitis recruited from the outpatient rheumatology clinics of the study hospital. Primary outcome measure Disease-specific quality of life assessed by the Evaluation of Ankylosing Spondylitis Quality of Life (EASi-QoL). Results Of the 265 patients, 57% were 20–49 years of age, with a male preponderance (75.5%). Multiple stepwise linear regression analysis indicated that a higher disease activity, assessed by the Ankylosing Spondylitis Disease Activity Score, was significantly and independently associated with a lower quality of life in all four domains (physical function, disease activity, emotional well-being and social participation) of the EASi-QoL. In addition, various independent factors, including educational level, nature of occupation, disease duration, dietary habit and body mass index, were significantly associated with different domains of the EASi-QoL. Conclusions Our findings indicated that, in addition to disease activity and perceived health status, a number of other factors could significantly impact the different aspects of quality of life in patients with ankylosing spondylitis, which warrant special consideration and support from healthcare providers.
Type of Medium:
Online Resource
ISSN:
2044-6055
,
2044-6055
DOI:
10.1136/bmjopen-2019-028966
Language:
English
Publisher:
BMJ
Publication Date:
2019
detail.hit.zdb_id:
2599832-8
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