In:
Angewandte Chemie, Wiley, Vol. 128, No. 9 ( 2016-02-24), p. 3239-3243
Abstract:
A new iron‐facilitated silver‐mediated radical 1,2‐alkylarylation of styrenes with α‐carbonyl alkyl bromides and indoles is described, and two new C−C bonds were generated in a single step through a sequence of intermolecular C(sp 3 )−Br functionalization and C(sp 2 )−H functionalization across the alkenes. This method provides an efficient access to alkylated indoles with broad substrate scope and excellent selectivity.
Type of Medium:
Online Resource
ISSN:
0044-8249
,
1521-3757
DOI:
10.1002/ange.201511624
Language:
English
Publisher:
Wiley
Publication Date:
2016
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505868-5
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514305-6
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505872-7
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1479266-7
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505867-3
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506259-7
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