In:
ChemistrySelect, Wiley, Vol. 7, No. 45 ( 2022-12-06)
Abstract:
Herein, we report a new, simple, one pot and chemoselective method for N‐methylation and N,N‐dimethylation of aliphatic and aromatic amines under ambient conditions using NHC ‐borane i.e 1,3‐dimethylimidazole‐2‐ylidene borane (diMe‐Imd‐BH 3 ), as reducing agent. The present strategy has significant advantages like mild reaction conditions, quick and effortless work‐up processes, and the use of non‐toxic inexpensive reagents. The amines with acid‐sensitive moieties are also methylated successfully.
Type of Medium:
Online Resource
ISSN:
2365-6549
,
2365-6549
DOI:
10.1002/slct.202203404
Language:
English
Publisher:
Wiley
Publication Date:
2022
detail.hit.zdb_id:
2844262-3
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