In:
Marine Life Science & Technology, Springer Science and Business Media LLC, Vol. 3, No. 1 ( 2021-02), p. 69-76
Abstract:
Ascidian-derived microorganisms are a significant source of pharmacologically active metabolites with interesting structural properties. When discovering bioactive molecules from ascidian-derived fungi, two new phenols, roussoelins A ( 1 ) and B ( 2 ), and ten known polyketides ( 3 – 12 ) were isolated from the ascidian-derived fungus Roussoella siamensis SYSU-MS4723. The planar structure of compounds 1 and 2 was established by analysis of HR-ESIMS and NMR data. The conformational analysis of the new compounds was assigned according to coupling constants and selective gradient NOESY experiments, and absolute configurations were completed by the modified Mosher’s method. Among the isolated compounds, 1 , 2 , and 9 showed moderate antioxidant capacity. Graphical abstract
Type of Medium:
Online Resource
ISSN:
2096-6490
,
2662-1746
DOI:
10.1007/s42995-020-00066-8
Language:
English
Publisher:
Springer Science and Business Media LLC
Publication Date:
2021
detail.hit.zdb_id:
3006215-9
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