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  • 1
    In: American Heart Journal, Elsevier BV, Vol. 178 ( 2016-08), p. 190-197
    Type of Medium: Online Resource
    ISSN: 0002-8703
    RVK:
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2016
    detail.hit.zdb_id: 2003210-9
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  • 2
    In: Circulation: Cardiovascular Quality and Outcomes, Ovid Technologies (Wolters Kluwer Health), Vol. 6, No. suppl_1 ( 2013-05)
    Abstract: Background: Explaining the risks and benefits of recombinant tissue plasminogen activator (rt-PA) occurs in a hurried conversation in the emergency department and may not be fully grasped by patients and their caregivers. Risk models describing the heterogeneity of benefits from rt-PA in acute ischemic stroke (AIS) have been created, but are not used in routine clinical practice. To develop a tool (RESOLVE) for modeling each patient’s benefits and risks for rt-PA, we conducted qualitative interviews with survivors, their caregivers and emergency physicians to inform the design and improve usability. Methods: A multidisciplinary research team conducted qualitative research through 10 focus groups of survivors and caregivers. We obtained feedback on their preferred role, desired information and their impressions of alternative formats for presenting risk and benefits. Three emergency physicians from 2 sites have been interviewed (with 〉 15 additional physician interviews being currently conducted, the results of which will supplement these preliminary data at the time of presentation). Results: Survivors and caregivers (63 participants: 39 stroke survivors; 43% male) express a need for more information, including specific risks and benefits to treatment. In general, both groups desired an active role in the acute stroke treatment decision. In contrast, the initial physician interviews indicated a hesitancy to provide NINDS data to patients and caregivers, skepticism of the existing data and cultural barriers to the use of rt-PA in AIS, the latter acquired through residency training or the opinions of their clinical colleagues. The interviewed clinicians, however, felt more positive about using rt-PA when a neurologist was readily available to support the decision. Conclusions: Preliminary findings suggest reluctance by emergency physicians to share data about the benefits of rt-PA to stroke patients and their caregivers, despite the desire of the latter for such information. While the additional planned interviews will be needed to confirm these findings, preliminary insights suggest a compelling need to overcome the reticence of emergency physicians to use clinical data to better engage patients in making a shared decision about rt-PA in AIS.
    Type of Medium: Online Resource
    ISSN: 1941-7713 , 1941-7705
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2013
    detail.hit.zdb_id: 2453882-6
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  • 3
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 2015
    In:  Circulation: Cardiovascular Quality and Outcomes Vol. 8, No. suppl_2 ( 2015-05)
    In: Circulation: Cardiovascular Quality and Outcomes, Ovid Technologies (Wolters Kluwer Health), Vol. 8, No. suppl_2 ( 2015-05)
    Abstract: Background: Cardiac arrest (CA) claims an estimated 300,000 lives in America each year even with cardio-pulmonary resuscitation (CPR) efforts. Additionally, of the patients who survive CPR and are discharged, many have suffered anoxic brain injury. Clinically, mild therapeutic hypothermia (TH) immediately post CA increases the odds of survival as well as improves neurological recovery and outcomes 6 months post-CA. Studies report that a small percent of CA patients recall their experience, but little is known regarding patient recall of hypothermia treatment post CA. This qualitative study seeks to understand the experience of survivors of CA and TH. Methods: A qualitative phenomenology study was conducted at a single center with survivors 12-24 months following CA and TH. Face-to-face or telephone interviews were audio recorded with each subjects’ permission and then transcribed verbatim. Transcripts were read in their entirety and searched for meaning-units that coalesced into themes. Consensus was achieved by all 3 nurse researchers and member-checked by being posed to a panel of survivors (1 was a subject of this study) which demonstrated thematic saturation yielding credible and trustworthy findings. Results: Six 6 survivors (67% [4 of 6] male, age 19-72 years) were interviewed. Four overall themes emerged: Memory gap - CA- “I can tell you what people told me, because I don’t remember it” and TH -“I don’t remember being cold or uncomfortable or anything like that” ; Filling in the gaps - “Several doctors, from what I understand, told my sister that I would have at least 70% brain loss if I was to wake up” “Everything was told to me”; and Misconceptions - “Even though I have a pacemaker/defibrillator it only operates one side; it doesn’t operate the whole heart. At least that’s what they told me anyway” “Of course, they told me if (my heart rate) got to 300, my heart would explode” ; and Divine coincidence - “My son had just taken a CPR course” “There was a nurse in the restaurant I was at” . Additionally, several patients provided unsolicited compliments of the staff - “I got absolutely outstanding care there ¼ I believe because they got me into hypothermia protocol so quickly, that was probably one of the contributing factors to my success” . Though one patient stated “I wish they’d left me alone” as he had unknowingly been resuscitated against his wishes. Conclusions: Survivors of CA and TH report memory gaps, and then strive to fill in the gaps by family and staff descriptions. Additionally, survivors easily identified an unexplained coincidence that they felt allowed them to successfully recover from their CA. Further study is warranted regarding whether the creation of a specific treatment plan to assist in the accurate recall and story would enhance survivors and family in recovery.
    Type of Medium: Online Resource
    ISSN: 1941-7713 , 1941-7705
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2015
    detail.hit.zdb_id: 2453882-6
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  • 4
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 2014
    In:  Circulation: Cardiovascular Quality and Outcomes Vol. 7, No. suppl_1 ( 2014-07)
    In: Circulation: Cardiovascular Quality and Outcomes, Ovid Technologies (Wolters Kluwer Health), Vol. 7, No. suppl_1 ( 2014-07)
    Abstract: Background: Communicating the risks and benefits of recombinant tissue plasminogen activator (rt-PA) for the treatment of acute ischemic stroke (AIS) is complex and often a hurried conversation in the emergency department (ED). Visual decision aids have been shown to be superior to standard treatment decision counseling and useful in emergency decision-making. Current rt-PA tools primarily focus on harmful risks while minimizing the positive benefits of treatment. Despite evidence to support enhancement of patient understanding of rt-PA treatment, use of these materials remains low. This study explored patient and family caregiver (CG) recall of rt-PA information provided, and comprehension of AIS and rt-PA education prior to piloting an enhanced individualized risk and benefit decision tool for rt-PA treatment in the ED. Methods: The goal is to interview 150 consecutive AIS rt-PA eligible patients and their CG to obtain feedback on the type of information (verbal or visual), comprehension and recall of risks and benefits provided in the ED. Currently 20 individuals (stroke patients = 8 and CG =12) at one large metropolitan medical center have completed the study. The participants were 35% (7/20) male; mean age 55.9 years, and 100% (20/20) of the survivors received rt-PA. Findings: All participants (20/20) received information on treatment options for AIS education in the ED. Ninety five percent (19/20) of patients did not recall receiving any visual material used in education of risks and benefits. Most patients (18/20) reported understanding that a stroke was caused by a clot in the brain, however only 30% (6/20) recalled having heard of rt-PA prior to coming to the hospital. Forty-five percent (9/20) of the subjects perceived the descriptions of rt-PA with its risks and benefits as being completely clear whereas 20% (4/20) reported they were not at all clear. Conclusions: Preliminary findings showed that less than half of the patients and CG felt the education was clear. However additional interviews are planned. Preliminary insights suggest an opportunity to use an individualized risk and benefit decision tool to inform and engage patients and CG regarding treatment decisions. We believe this can be accomplished without increasing the door to needle time in administration of rt-PA.
    Type of Medium: Online Resource
    ISSN: 1941-7713 , 1941-7705
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2014
    detail.hit.zdb_id: 2453882-6
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  • 5
    In: Journal of the American College of Cardiology, Elsevier BV, Vol. 61, No. 18 ( 2013-05), p. 1847-1852
    Type of Medium: Online Resource
    ISSN: 0735-1097
    RVK:
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2013
    detail.hit.zdb_id: 1468327-1
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  • 6
    In: Stroke, Ovid Technologies (Wolters Kluwer Health), Vol. 44, No. suppl_1 ( 2013-02)
    Abstract: Background: Explaining the benefits and risks of tissue plasminogen activator (tPA) is typically done through hurried verbal explanations in the emergency department, but it may not be understood by patients and caregivers. However, spending more time to explain the risks and benefits may delay the administration of tPA. We sought to develop a decision aid tool to facilitate this communication. Methods: A multidisciplinary research team searched available materials of stroke descriptions intended for a lay audience. The research team and medical illustrator also developed different formats of presenting results from the NINDS tPA trial. We conducted focus groups of stroke survivors and their caregivers at two medical centers to provide feedback on what information should be communicated and how it should be presented. Results: To date, we have convened three focus groups. We have enrolled 12 stroke survivors with a mean age of 54. Two had received tPA. We also enrolled three caregivers with a mean age of 68. Survivors typically did not recall being educated about acute stroke or its treatment during the hospitalization. Participants preferred broadening the definition of a “good” outcome to functional independence (i.e. modified Rankin score of 0-2) over a narrower one of being symptom-free. They also preferred viewing information about the increased chance of a good outcome rather than the decreased chance of a bad outcome such as death. Participants’ opinions sometimes differed from researchers’, such as the choice of colors to depict good outcome or death and the preference of simple bar graphs over pictographs. Conclusions: The different opinions between researchers and patients and caregivers highlight the need to obtain input from all stakeholders in designing effective decision aid tools. Further focus groups are planned to refine the decision-aid tool. We also plan to pilot-test the implementation of this tool in the workflow of managing patients with stroke in the emergency department.
    Type of Medium: Online Resource
    ISSN: 0039-2499 , 1524-4628
    RVK:
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2013
    detail.hit.zdb_id: 1467823-8
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  • 7
    In: Circulation: Cardiovascular Quality and Outcomes, Ovid Technologies (Wolters Kluwer Health), Vol. 12, No. 2 ( 2019-02)
    Abstract: Drug-eluting stents reduce the risk of restenosis in patients undergoing percutaneous coronary intervention, but their use necessitates prolonged dual antiplatelet therapy, which increases costs and bleeding risk, and which may delay elective surgeries. While 〉 80% of patients in the United States receive drug-eluting stents, less than a third report that their physicians discussed options with them. Methods and Results: An individualized shared decision-making (SDM) tool for stent selection was designed and implemented at 2 US hospitals. In the postimplementation phase, all patients received the SDM tool before their procedure, with or without decision coaching from a trained nurse. All patients were interviewed with respect to their knowledge of stents, their participation in SDM, and their stent preference. Between May 2014 and December 2016, 332 patients not receiving the SDM tool, 113 receiving the SDM tool with coaching, and 136 receiving the tool without coaching were interviewed. Patients receiving the SDM tool + coaching, as compared with usual care, demonstrated higher knowledge scores (mean difference +1.8; P 〈 0.001), reported more frequent participation in SDM (odds ratio=2.96; P 〈 0.001), and were more likely to state a stent preference (odds ratio=2.00; P 〈 0.001). No significant differences were observed between the use of the SDM tool without coaching and usual care. For patients who voiced a stent preference, concordance between stent desired and stent received was 98% for patients who preferred a drug-eluting stent and 50% for patients who preferred a bare metal stent. The SDM tool (with or without coaching) had no impact on stent selection or concordance. Conclusions: An SDM tool for stent selection was associated with improvements in patient knowledge and SDM only when accompanied by decision coaching. However, the SDM tool (with or without coaching) had no impact on stent selection or concordance between patients’ stent preference and stent received, suggesting that physician-level barriers to SDM may exist. Clinical Trial Information URL: https://www.clinicaltrials.gov . Unique Identifier: NCT02046902.
    Type of Medium: Online Resource
    ISSN: 1941-7713 , 1941-7705
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2019
    detail.hit.zdb_id: 2453882-6
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  • 8
    Online Resource
    Online Resource
    Elsevier BV ; 2012
    In:  Journal of the American College of Cardiology Vol. 59, No. 13 ( 2012-03), p. E288-
    In: Journal of the American College of Cardiology, Elsevier BV, Vol. 59, No. 13 ( 2012-03), p. E288-
    Type of Medium: Online Resource
    ISSN: 0735-1097
    RVK:
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2012
    detail.hit.zdb_id: 1468327-1
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  • 9
    In: Circulation: Cardiovascular Quality and Outcomes, Ovid Technologies (Wolters Kluwer Health), Vol. 8, No. 6_suppl_3 ( 2015-10)
    Abstract: National guidelines endorse recombinant tissue-type plasminogen activator (r-tPA) in eligible patients with acute ischemic stroke to improve patients’ functional recovery. However, 23% to 40% of ideal candidates with acute ischemic stroke for reperfusion are not treated, perhaps because of the difficulty in explaining the benefits and risks of r-tPA within the frenetic pace of emergency department care. To support better knowledge transfer and creation of a shared decision-making tool, we conducted qualitative interviews to define the information needs and preferred presentation format for stroke survivors, caregivers, and clinicians considering r-tPA treatment. Methods and Results— A multidisciplinary team used qualitative research methods to identify informational needs and strategies for describing the benefits and risks of r-tPA in a clinical setting. Through focus groups (n=10) of stroke survivors (n=39) and caregivers (n=24) and individual interviews with emergency physicians (n=23) and advanced practice nurses (n=20), several themes emerged. Survivors and caregivers preferred a broader definition of a good outcome (independence, rather than no significant disability), simpler graphs as compared with detailed pictographs, and presentation of both population and individualized benefits (framed positively) and risk of receiving r-tPA. Some physicians expressed skepticism with the data and the ability to present risk/benefit information emergently, whereas other physicians and most advanced practice nurses thought such information would improve care. Physicians stressed the importance of presenting the risk of thrombolytic-related intracranial hemorrhage. Conclusions— This study suggests that a positively framed risk–benefit tool with graphical presentations of general and patient-specific risk estimates could support patients and providers in considering r-tPA for acute ischemic stroke. Clinical Trial Registration— URL: http://www.clinicaltrials.gov . Unique identifier: NCT01864928.
    Type of Medium: Online Resource
    ISSN: 1941-7713 , 1941-7705
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2015
    detail.hit.zdb_id: 2453882-6
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  • 10
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 2017
    In:  Circulation: Cardiovascular Quality and Outcomes Vol. 10, No. suppl_3 ( 2017-03)
    In: Circulation: Cardiovascular Quality and Outcomes, Ovid Technologies (Wolters Kluwer Health), Vol. 10, No. suppl_3 ( 2017-03)
    Abstract: Background: Alteplase does not uniformly benefit patients with acute ischemic stroke (AIS). Variable times since symptom onset, age, comorbidities and symptom severity add much uncertainty to physicians’ ability to knowledgeably individualize clinical decision-making. This contributes to the recent controversy regarding ACEP-authored expert guidelines which support presentation of risks and benefits and a process of shared decision-making. We previously developed the RESOLVE decision support tool for generating personalized estimates of the benefits and risk of alteplase and developed implementation strategies for both the Emergency Department (ED) and Telehealth settings. This study was a survey of physicians in rural hospitals within a large stroke network to quantify physician’s satisfaction and confidence in treating AIS after having access to the RESOLVE tool. Methods: To provide rural ED physicians access to the RESOLVE decision support tool prior to the administration of alteplase for AIS, nurses at a centralized Telehealth system were trained to enter the data elements required to run the RESOLVE model and fax the tool to the rural hospital immediately, while the provider was waiting for a neurologist’s consultation from the comprehensive stroke center. We then conducted semi-structured interviews of rural hospital physicians who used the tool as soon as possible. We interviewed 14/28 physicians at 7 critical access hospitals, 6 rural community hospital and one urban public that used the RESOLVE tool in decision making during a 6 month pilot. Results: Providers strongly agreed the tool was helpful in discussing potential risks and benefits with the patient or family. Having the knowledge of the individualized patient risk of hemorrhage, and being able to inform the patient/family, was a theme that emerged from qualitative analyses of the interviews. “Knowing the risk of hemorrhage was only 3% made me more comfortable giving IV tPA” - ED Physician, Critical Access Hospital “[I] used it to discuss the risk of hemorrhage with the patient/family. That was very helpful.” - ED Physician, Urban Public Hospital “…used it to discuss the benefits and risks, having it helped me to know what to discuss with the patient/family.” - ED Physician, Rural Community Hospital Study limitations included the difficulty in interviewing physicians due to 12-hour work shift and those practicing as a locum tenens. Additionally, the timing and fax location was a limitation in some physicians seeing the tool prior to prior to treatment. Conclusions: The preliminary results showed the rural hospital providers saw value in the RESOLVE tool while discussing the risks and benefits with patient/family. Future strategies would include process changes to expedite the faxing of the RESOLVE tool.
    Type of Medium: Online Resource
    ISSN: 1941-7713 , 1941-7705
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2017
    detail.hit.zdb_id: 2453882-6
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