In:
International Journal of Sports Medicine, Georg Thieme Verlag KG, Vol. 43, No. 07 ( 2022-06), p. 616-624
Abstract:
Adipokines and cardiorespiratory fitness (CRF) are associated with the
(patho)physiology of cardiometabolic diseases. Whether CRF and adipokines are related is unclear. We investigated associations of CRF with leptin,
adiponectin, chemerin, resistin and vaspin. Data from the population-based Study of Health in Pomerania was used (n=1,479; median age 49 years;
51% women). Cardiopulmonary exercise testing was used to measure CRF. Circulating adipokine concentrations were measured by enzyme-linked
immunosorbent assay. The association between CRF and adipokines was assessed using multivariable sex-specific quantile regression models. Higher maximum
oxygen uptake was significantly associated with lower leptin (men:−0.11 ng/ml; 95%-confidence interval
[CI] :−0.18 to−0.03 ng/ml; p 〈 0.005;
women:−0.17 ng/ml; 95%-CI:−0.33 to−0.02 ng/ml; p 〈 0.05) and chemerin
(men:−0.26 ng/ml; 95%-CI:−0.52 to−0.01 ng/ml; p 〈 0.05;
women:−0.41 ng/ml; 95%-CI:−0.82 to−0.01 ng/ml; p 〈 0.05) as well as higher
adiponectin concentrations (men: 0.06 µg/ml; 95%-CI: 0.02 to 0.11 µg/ml; p 〈 0.05;
women: 0.03 µg/ml; 95%-CI:−0.05 to 0.10 µg/ml; p=0.48). We found that CRF was
inversely associated with leptin and chemerin in both sexes and positively associated with adiponectin only in men.
Type of Medium:
Online Resource
ISSN:
0172-4622
,
1439-3964
Language:
English
Publisher:
Georg Thieme Verlag KG
Publication Date:
2022
detail.hit.zdb_id:
2041541-2
SSG:
31
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