In:
Synlett, Georg Thieme Verlag KG, Vol. 32, No. 12 ( 2021-07), p. 1187-1191
Abstract:
4,5,6,7-Tetrahydroisobenzofurans, corresponding to the AC(D)E ring structure of viridin and equipped with required substituents on the A-ring, were synthesized with high regio- and stereoselectivities via the Diels–Alder adduct of a furan derivative and maleic anhydride. The key steps of this work include the regioselective opening of a tetrahydrofuran ring, a stereoselective epoxidation, and an AlMe3-mediated regioselective epoxide opening followed by stereoselective C-methylation.
Type of Medium:
Online Resource
ISSN:
0936-5214
,
1437-2096
Language:
English
Publisher:
Georg Thieme Verlag KG
Publication Date:
2021
detail.hit.zdb_id:
2042012-2
Permalink