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  • 1
    Online Resource
    Online Resource
    American Academy of Pediatrics (AAP) ; 2016
    In:  Hospital Pediatrics Vol. 6, No. 4 ( 2016-04-01), p. 226-233
    In: Hospital Pediatrics, American Academy of Pediatrics (AAP), Vol. 6, No. 4 ( 2016-04-01), p. 226-233
    Abstract: Well-appearing febrile infants with viral illnesses cannot be distinguished from those with occult life-threatening infections. Infants with respiratory viruses are less likely to have serious bacterial infections; however, current risk-stratification criteria predate widespread viral testing and there are limited data to safely inform physician management with this now common diagnostic tool. This study sought to explore the possible impact of respiratory virus testing on clinical decision-making for the management of febrile young infants & lt;6 weeks old. METHODS: A scenario-based survey was sent to emergency department (ED) and inpatient physicians at all 16 Canadian tertiary pediatric centers. Participants were asked questions regarding management decisions with and without results of respiratory virus testing. RESULTS: Response rate was 78% (n = 330; 190 ED, 140 inpatient). Detection of a respiratory virus reduced admission rates among 3-week-old (83% vs 95%, P & lt; .001) and 5-week-old infants (36% vs 52%, P & lt; .001). Similarly, empirical antibiotic treatment was decreased by detection of a respiratory virus for 3-week-old (65% vs 92%, P & lt; .001) and 5-week-old infants (25% vs 39%, P & lt; .001). Management of 5-week-old infants differed between ED and inpatient physicians, both in the presence and absence of a respiratory virus. There was no consensus among inpatient physicians regarding admission duration for well infants with a detectable respiratory virus and otherwise negative workup. CONCLUSIONS: Respiratory virus testing appears to influence clinical decision-making for febrile infants & lt;6 weeks, reducing both rates of admission and antimicrobial treatment. Important work is needed to better understand how to safely incorporate viral testing for the management of this vulnerable patient population.
    Type of Medium: Online Resource
    ISSN: 2154-1663 , 2154-1671
    Language: English
    Publisher: American Academy of Pediatrics (AAP)
    Publication Date: 2016
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  • 2
    In: The Journal of Pediatrics, Elsevier BV, Vol. 210 ( 2019-07), p. 20-25.e2
    Type of Medium: Online Resource
    ISSN: 0022-3476
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2019
    detail.hit.zdb_id: 2005245-5
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  • 3
    In: Journal of Neurotrauma, Mary Ann Liebert Inc, Vol. 39, No. 1-2 ( 2022-01-01), p. 144-150
    Type of Medium: Online Resource
    ISSN: 0897-7151 , 1557-9042
    Language: English
    Publisher: Mary Ann Liebert Inc
    Publication Date: 2022
    detail.hit.zdb_id: 2030888-7
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  • 4
    Online Resource
    Online Resource
    Oxford University Press (OUP) ; 2020
    In:  Paediatrics & Child Health Vol. 25, No. Supplement_2 ( 2020-08-19), p. e32-e32
    In: Paediatrics & Child Health, Oxford University Press (OUP), Vol. 25, No. Supplement_2 ( 2020-08-19), p. e32-e32
    Abstract: The incidence of children presenting to an Emergency Department (ED) following concussion has increased markedly in recent decades. Headache is the most commonly associated symptom and recent guidelines emphasize the importance of analgesia, yet evidence to inform treatment of post-concussive headache (PCH) is completely lacking. Objectives This study sought to characterize abortive therapies used to treat PCH among physicians in academic pediatric EDs and to determine whether duration of symptoms and/or headache intensity influence treatment strategies. Design/Methods A scenario-based electronic survey was sent to physician members of the Pediatric Emergency Research Canada (PERC) database. Participants were asked questions regarding management when presented with cases of an adolescent presenting to the ED with PCH refractory to appropriate doses of acetaminophen and ibuprofen. Scenarios differed only by duration of symptoms (48-hours versus 1-month post-injury), as well as headache intensity (moderate versus severe). Descriptive statistics are reported. Results Survey response rate was 63% (n/N=137/219). At 48 hours post-injury, 93% of physicians reported that they would initiate treatment for a headache rated as severe. The most commonly selected medications to treat PCH were metoclopramide (72%), an intravenous bolus of normal saline (47%) and non-steroidal anti-inflammatories (NSAIDS; 35%). There was wide variability among second line strategies for refractory pain following first-line treatment. When presented with PTH pain rated moderate in severity, 63% of respondents would change their management compared to severe pain, with 66% no longer offering pharmacologic treatment in the ED and most frequently selecting oral NSAIDS (58%) when electing to initiate treatment. Medication selection was unchanged when presented with a patient reporting severe PCH at 1 month compared to 48-hours post-injury. Conclusion Most physicians would treat pediatric PCH in the ED for a patient reporting severe pain, however, pain rated as moderate was less likely to receive abortive treatment. Metoclopramide was the most frequently selected medication for analgesia for severe pain. Future research should aim to establish the efficacy of this and comparative treatments for PTH in children.
    Type of Medium: Online Resource
    ISSN: 1205-7088 , 1918-1485
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2020
    detail.hit.zdb_id: 2174400-2
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