In:
Chemistry & Chemical Technology, Lviv Polytechnic National University, Vol. 10, No. 2 ( 2016-06-15), p. 159-172
Abstract:
The method for synthesis of a new class of amphiphilic oligoesters of pyromellitic acid is developed. As hydrophilic fragments polyethylene glycols or polyethylene glycol mono methyl ethers were used, as lipophilic ones – primary fatty alcohols or cholesterol. The structure of the synthesized oligoesters was confirmed by IR- and PMR-spectroscopy. The oligoesters could solubilize water-insoluble substances, for example such effective antitumor lipophilic drug as curcumin. The high solubilization capacity of the OEPA assemblies and their biodegradability, as well as other properties (size distribution, ζ-potential) make the oligoesters considered as promising materials for the design of drug delivery systems.
Type of Medium:
Online Resource
ISSN:
1996-4196
,
1996-4196
Uniform Title:
Synthesis and Selfassambling of Amphiphilic Oligoesters Based on Pyromellitic Acid
DOI:
10.23939/chcht10.02.159
Language:
Unknown
Publisher:
Lviv Polytechnic National University
Publication Date:
2016
detail.hit.zdb_id:
2735863-X
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