GLORIA

GEOMAR Library Ocean Research Information Access

X

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Desai, Pankaja  (4)
  • Holland, Thomas Monroe  (4)
  • 1
    Online Resource
    Online Resource
    Examination of a composite walking measure to inform physical activity guidelines for improving or maintaining cognitive functioning : Epidemiology / Risk and protective factors in MCI and dementia
    Wiley ; 2020
    In:  Alzheimer's & Dementia Vol. 16, No. S10 ( 2020-12)
    Details
    In: Alzheimer's & Dementia, Wiley, Vol. 16, No. S10 ( 2020-12)
    Abstract: Fewer than half of all U.S. adults achieve recommended levels of aerobic activity (150 minutes or more at moderate intensity) (CDC, 2013; USDHHS, 2018). Information related to frequency, dose, duration, and intensity of walking needed to positively impact cognitive function in older adults remains unclear in current U.S. Physical Activity Guidelines (Piercey et al., 2018; Paterson et al., 2010). A paucity of studies have been conducted which examine the association between physical activity (PA), much less PA types, and cognitive function, using a longitudinal, population‐based approach with a racially diverse sample, which limits generalizability of existing findings. Self‐report PA measures often evaluate types of walking separately (e.g., walking for exercise, leisure time, occupational, transportation‐related), without considering total effect of all types of walking on cognitive function. A composite walking measure could provide a more comprehensive picture of perceived daily walking. We examine the association between composite walking and cognitive function and perceptual speed among participants in the Chicago Health and Aging Project (CHAP) over time. Method CHAP is a longitudinal, population‐based study, which examined risk factors of Alzheimer’s Disease and chronic conditions among diverse older adults (Bienas et al., 2003). Data collection included self‐report walking frequency and duration, demographics, chronic conditions, cognitive activities, APOE ϵ4, and cognitive function during three‐year cycles. A composite walking measure was developed. Composite walking was divided into three categories determined by sample size: no walking, 〈 105 minutes/ week, and 〉 105 minutes/ week of walking. Mixed effects regression analyses were conducted to test the association between walking and cognitive function and perceptual speed. Result The sample consists of N=4,320 CHAP participants (Black/ African American: 65%; Female: 65%; Mean Education: 13 years; Mean Age: 75 years). Findings show that composite walking had a statistically significant association with global cognitive function (category 2 β=.0084, p=.0389; category 3 β=.0099, p=.0187) and perceptual speed (category 2 β=.0117, p=.0164; category 3 β=.0162, p=.0013), after controlling for covariates. Conclusion Although it is best to follow PA guidelines, walking for lesser than the recommended amount may still be beneficial for cognitive function, which is useful for promotion of PA among sedentary older adults.
    Type of Medium: Online Resource
    ISSN: 1552-5260 , 1552-5279
    URL: Issue
    URL: Article
    DOI: 10.1002/alz.v16.S10
    DOI: 10.1002/alz.044064
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2201940-6
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 2
    Online Resource
    Online Resource
    Effects of the MIND diet and physical activity on cognitive domains in the elderly
    Wiley ; 2021
    In:  Alzheimer's & Dementia Vol. 17, No. S10 ( 2021-12)
    Details
    In: Alzheimer's & Dementia, Wiley, Vol. 17, No. S10 ( 2021-12)
    Abstract: Diet and physical activity (PA) are important for cognitive health, but few studies have examined whether there is a synergistic relationship with cognitive decline in older adults. In this study, we investigated whether the combination of a high MIND diet score and high, device‐measured, PA has a stronger relationship with global cognitive decline and specific cognitive domains when compared to other combinations of MIND diet score and PA levels, Method We examined the association of MIND diet and PA interactions on global cognition and five cognitive domains in 264 participants without cognitive impairment from the Rush Memory and Aging Project. Diet was assessed using a validated 144‐item food frequency questionnaire with objective physical activity measured by Actical. Cognition was assessed using a 19‐test cognitive battery from which a global composite score and 5 domains were derived. Participants (mean age = 79± SD 7.7 years; 75% female) were followed for an average of 6.3 ± SD 2.7 years and separated into 9 categorical combinations of MIND diet score and PA (high, moderate, low for MIND diet x high, moderate, low for PA), with low MIND diet and low PA serving as the reference. Linear mixed models adjusted for age sex, education, ApoE‐4, late life cognitive activity, self‐reported physical activity, smoking, and caloric intake. Result Adherence to a high MIND/high PA regimen over time versus low MIND/low PA was associated with a 62.5% slower rate of decline in global cognition (β=0.12, p=0.0001). We also found similar associations for episodic memory (β=0.13, p=0.0006), semantic memory (β=0.1, p=0.005), perceptual speed (β=0.05, p=0.03), and working memory (β=0.08, p=0.006) but not visuospatial ability (β=0.05, p=0.15.). Further, it was determined that the high MIND/high PA combination improved a broader range of cognitive domains over time, than either the high MIND/low PA, or low MIND/high PA, versus low MIND/low PA. (Figure 1) Conclusion Adherence to a high MIND diet/high PA regimen has a greater impact on cognitive decline and specific cognitive domains versus alternate combinations of MIND diet and Physical Activity.
    Type of Medium: Online Resource
    ISSN: 1552-5260 , 1552-5279
    URL: Issue
    URL: Article
    DOI: 10.1002/alz.v17.S10
    DOI: 10.1002/alz.056519
    Language: English
    Publisher: Wiley
    Publication Date: 2021
    detail.hit.zdb_id: 2201940-6
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 3
    Online Resource
    Online Resource
    Racial Differences in the Association of MIND Diet/Physical Activity Combinations and Cognition in older adults
    Wiley ; 2022
    In:  Alzheimer's & Dementia Vol. 18, No. S11 ( 2022-12)
    Details
    In: Alzheimer's & Dementia, Wiley, Vol. 18, No. S11 ( 2022-12)
    Abstract: Diet and physical activity (PA) are important factors associated with improved cognition. Few studies have investigated the synergistic association with cognitive decline and further, whether the association differs by race. In this study, we investigate whether the observed association of high MIND diet score/high self‐reported PA and cognitive decline is different between African Americans (AA’s) and European Americans (EA’s). Method We examined the association of baseline MIND diet and PA combinations on cognition in 3,657 participants (2206 AAs and 1451 EAs; mean age = 73.2±SD5.8 years) from the Chicago Health and Aging Project. Diet was assessed using a validated 144‐item food frequency questionnaire; self‐reported PA was measured by frequency of engagement in six activities. Cognition was evaluated using a four‐test cognitive battery from which a global composite score and two domains were derived. Participants were followed on average 8.5±SD4.8 years and separated into 9 combinations of MIND diet score and PA (high, moderate, low for MIND diet and high, moderate, low, for PA). Using linear mixed models we examined the rate of cognitive decline; adjusting for age, sex, education, race, ApoE‐4, smoking, and caloric intake. Subsequent models were stratified by race to investigate potential differences in the association of diet and PA combinations with cognitive decline. Result Participants who reported high MIND/high PA had a slower rate of decline in global cognition (β = 0.015, 24.87% slower, p = 0.007), memory score (β = 0.014, 31.86% slower, p = 0.042) and improved MMSE (β = 0.023, 33.62% improvement, p 〈 0.001) when compared to participants with low MIND/low PA. In race stratified models, we found that in European Americans, high MIND/high PA was associated with slower rates of decline in global cognition (β = 0.028, 37.1% slower, p = 0.007), memory score (β = 0.026, 48.59% slower, p = 0.033) and improved MMSE (β = 0.050, 50.0% improvement, p 〈 0.0001) versus low MIND diet/low PA. However, only an improved MMSE (β = 0.017, 27.11% improvement, p = 0.033) was observed to be associated in African Americans. Conclusion High adherence to MIND diet/physical activity is associated with slower cognitive decline, regardless of race. However, the breadth of these associations may differ by race. Additional studies are required to elucidate the potential racial differences observed and determine which interventions are most impactful.
    Type of Medium: Online Resource
    ISSN: 1552-5260 , 1552-5279
    URL: Issue
    URL: Article
    DOI: 10.1002/alz.v18.S11
    DOI: 10.1002/alz.068089
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 2201940-6
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 4
    Online Resource
    Online Resource
    Dietary intake of the bioactive pelargonidin may slow decline in multiple cognitive abilities : Prevention (non‐pharmacological): Developing ADRD non‐pharmacological intervention targets
    Wiley ; 2020
    In:  Alzheimer's & Dementia Vol. 16, No. S10 ( 2020-12)
    Details
    In: Alzheimer's & Dementia, Wiley, Vol. 16, No. S10 ( 2020-12)
    Abstract: Research has demonstrated a positive relationship between cognitive abilities and dietary intake of flavonoids, bioactives found in foods that have known antioxidant and anti‐inflammatory characteristics. We advance past research by investigating the association of dietary intake of an anthocyanidin subclass constituent, pelargonidin, found in berries especially, strawberries, on change in global cognition, episodic memory, semantic memory, working memory, perceptual speed, and visuospatial ability. Methods This study was conducted in 961 Rush Memory and Aging Project (MAP), a prospective cohort study, consisting community‐dwelling participants in Chicago (aged 58 to 100 years), who were followed for an average of 6.3 (±2.7) years. MAP participants were asked to complete a validated semi‐quantitative food frequency questionnaire at baseline. Cognitive abilities were assessed annually using a battery of 19 standardized tests. Cognitive domain scores were regressed on baseline energy‐adjusted flavonoid pelargonidin, which was distributed into quartiles based on dietary intake in linear mixed models. Results Our analytical sample of 961 participants had an average age of 81.4 (±7.2) years, and 15 (±3) years of education, 74% were female, 22% had at least one APOE‐ɛ4 allele, and 42% had a smoking history. Higher intake of pelargonidin, intake was inversely associated with decline in global cognition and multiple cognitive domains. In models adjusted for age, sex, education, APOE‐ɛ4, late life cognitive activity, smoking and physical activity, dietary intake of the highest quartile versus lowest quartile of pelargonidin was associated with slower decline in global cognition (β estimate=0.02, p=0.03; p‐trend=0.02), episodic memory (β=0.03, p=0.045; p‐trend=0.03), semantic memory (β=0.03, p=0.02; p‐trend=0.02), perceptual speed (β=0.02, p=0.02; p‐trend=0.01) and visuospatial ability (β=0.03, p=0.02; p‐trend=0.050). Non‐significant working memory was suggestive (β=0.02, p=0.07; p‐trend=0.07). Conclusion Dietary intake of the anthocyanidin subclass constituent, pelargonidin, may slow decline of cognitive abilities in multiple domains with older age.
    Type of Medium: Online Resource
    ISSN: 1552-5260 , 1552-5279
    URL: Issue
    URL: Article
    DOI: 10.1002/alz.v16.S10
    DOI: 10.1002/alz.046260
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2201940-6
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...