In:
Rapid Communications in Mass Spectrometry, Wiley, Vol. 28, No. 21 ( 2014-11-15), p. 2363-2370
Abstract:
An unambiguous identification of compounds can be achieved by comparison of known fragmentation patterns. While the literature about fragmentation mechanisms of lignans, flavonoids and triterpenoids is few. So the present study analyses the fragmentation mechanisms of these compounds isolated from Streblus asper. METHODS Electrospray ionization ion trap mass spectrometry (ESI‐ITMS) and atmospheric pressure chemical ionization ion trap mass spectrometry (APCI‐ITMS) were used to obtain the MS n spectra of the compounds . By analyzing the differences between the ions, the fragmentation mechanisms of these compounds were explored. RESULTS Of the 29 compounds detected, 17, 7, and 5 were lignans, flavonoids and triterpenoids, respectively. The majority of lignans were found to give [M – H] – ions of sufficient abundance for MS n analyses. The flavonoids were prone to the loss of CO and H 2 O. The triterpenoids always lost one formic acid molecule and two hydrogens, or one H 2 O from [M – H] – to form the most abundant product ion in the MS n spectrum. CONCLUSIONS ESI/APCI‐ITMS were demonstrated to be fast, effective and practical tools to characterize the structures of flavonoids, triterpenoids and lignans. Results of the present study can help identify the analogous constituents by analyzing their MS n spectra. Copyright © 2014 John Wiley & Sons, Ltd.
Type of Medium:
Online Resource
ISSN:
0951-4198
,
1097-0231
Language:
English
Publisher:
Wiley
Publication Date:
2014
detail.hit.zdb_id:
2002158-6
detail.hit.zdb_id:
58731-X
SSG:
11
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