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  • Wiley  (2)
  • Daniel, Leticia  (2)
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  • Wiley  (2)
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  • 1
    Online Resource
    Online Resource
    Wiley ; 2017
    In:  Veterinary Surgery Vol. 46, No. 4 ( 2017-05), p. 549-558
    In: Veterinary Surgery, Wiley, Vol. 46, No. 4 ( 2017-05), p. 549-558
    Abstract: To improve the prediction of fractures in dogs with bone tumors of the distal radius by identifying computed tomography (CT) indices that correlate with antebrachial bone strength and fracture location. Study design Prospective experimental study. Animals Dogs with antebrachial osteosarcoma (n = 10), and normal cadaver bones (n=9). Methods Antebrachia were imaged with quantitative CT prior to biomechanical testing to failure. CT indices of structural properties were compared to yield force and maximum force using Pearson correlation tests. Results Straight beam failure (Fs), axial rigidity, curved beam failure (Fc), and craniocaudal bending moment of inertia (MOICrCd) CT indices most highly correlated (0.77  〉  R  〉  0.57) with yield and maximum forces when iOSA‐affected and control bones were included in the analysis. Considering only OSA‐affected bones, Fs, Fc, and axial rigidity correlated highly (0.85  〉  R  〉  0.80) with maximum force. In affected bones, the location of minimum axial rigidity and maximum MOICrCd correlated highly (R  〉  0.85) with the actual fracture location. Conclusions CT‐derived axial rigidity, Fs, and MOICrCd have strong linear relationships with yield and maximum force. These indices should be further evaluated prospectively in OSA‐affected dogs that do, and do not, experience pathologic fracture.
    Type of Medium: Online Resource
    ISSN: 0161-3499 , 1532-950X
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2017
    detail.hit.zdb_id: 1491071-8
    SSG: 22
    Location Call Number Limitation Availability
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  • 2
    Online Resource
    Online Resource
    Wiley ; 2017
    In:  Veterinary Surgery Vol. 46, No. 4 ( 2017-05), p. 539-548
    In: Veterinary Surgery, Wiley, Vol. 46, No. 4 ( 2017-05), p. 539-548
    Abstract: To determine the influence of neoplasia on the biomechanical properties of canine antebrachia. Study design Ex vivo biomechanical study. Sample population : Osteosarcoma (OSA)‐affected canine antebrachia (n = 12) and unaffected canine antebrachia (n = 9). Methods Antebrachia were compressed in axial loading until failure. A load‐deformation curve was used to acquire the structural mechanical properties of neoplastic and unaffected specimens. Structural properties and properties normalized by body weight (BW) and radius length were compared using analysis of variance (ANOVA). Modes of failure were compared descriptively. Results Neoplastic antebrachia fractured at, or adjacent to, the OSA in the distal radial diaphysis. Unaffected antebrachia failed via mid‐diaphyseal radial fractures with a transverse cranial component and an oblique caudal component. Structural mechanical properties were more variable in neoplastic antebrachia than unaffected antebrachia, which was partially attributable to differences in bone geometry related to dog size. When normalized by dog BW and radial length, strength, stiffness, and energy to yield and failure, were lower in neoplastic antebrachia than in unaffected antebrachia. Conclusions OSA of the distal radial metaphysis in dogs presented for limb amputation markedly compromises the structural integrity of affected antebrachia. However, biomechanical properties of affected bones was sufficient for weight‐bearing, as none of the neoplastic antebrachia fractured before amputation. The behavior of tumor invaded bone under cyclic loading warrants further investigations to evaluate the viability of in situ therapies for bone tumors in dogs.
    Type of Medium: Online Resource
    ISSN: 0161-3499 , 1532-950X
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2017
    detail.hit.zdb_id: 1491071-8
    SSG: 22
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
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