In:
Circulation, Ovid Technologies (Wolters Kluwer Health), Vol. 109, No. 9 ( 2004-03-09), p. 1085-1088
Abstract:
Background— We used intravascular ultrasound (IVUS) to evaluate recurrence after sirolimus-eluting stent (SES) implantation treatment of in-stent restenosis (ISR). Methods and Results— Forty-eight ISR lesions (41 patients with objective evidence of ischemia) were treated with SES. Recurrent ISR was identified in 11 lesions (all focal); repeat revascularization was performed in 10. These were compared with 16 patients (19 lesions) without recurrence as documented by angiography. Nine of 11 recurrent lesions had a minimum stent area (MSA) 〈 5.0 mm 2 versus 5 of 19 nonrecurrent lesions ( P =0.003); 7 of 11 recurrent lesions had an MSA 〈 4.0 mm 2 versus 4 of 19 nonrecurrent lesions ( P =0.02); and 4 of 11 recurrent lesions had an MSA 〈 3.0 mm 2 versus 1 of 19 nonrecurrent lesions ( P =0.03). A gap between SESs was identified in 3 of 11 recurrences versus 1 of 19 nonrecurrent lesions. Conclusions— Stent underexpansion is a significant cause of failure after SES implantation treatment of ISR.
Type of Medium:
Online Resource
ISSN:
0009-7322
,
1524-4539
DOI:
10.1161/01.CIR.0000121327.67756.19
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
2004
detail.hit.zdb_id:
1466401-X
Permalink