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  • 1
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    The Association between Dietary Purine Intake and Mortality: Evidence from the CHNS Cohort Study
    MDPI AG ; 2022
    In:  Nutrients Vol. 14, No. 9 ( 2022-04-21), p. 1718-
    Details
    In: Nutrients, MDPI AG, Vol. 14, No. 9 ( 2022-04-21), p. 1718-
    Kurzfassung: Objectives: To investigate the association between dietary purine intake and mortality among Chinese adults. Methods: Based on data from the 2004–2015 China Health and Nutrition Survey (CHNS) and the corresponding edition of China Food Composition, the average purine intake per day (mg/day) from 2004 to 2011 was calculated, and the surveyed population was divided into five groups by quintiles. The outcome event and timepoint of concern were defined as death and time, respectively, as reported by family members, recorded until the 2015 survey. Cox proportional hazards regression was used to estimate the hazard ratios (HRs) with 95% confidence intervals (CIs) for death. The possibly nonlinear relationship between purine intake and mortality was examined with restricted cubic splines. Results: We included 17,755 subjects, and the average purine intake among them was 355.07 ± 145.32 mg/day. Purine intake was inversely associated with mortality (Ptrend 〈 0.001). Compared with the lowest quintiles of purine intake, the highest quintiles (HR = 0.60; 95% CI: 0.46, 0.77) showed a significant association with lower mortality. The negative association with mortality was mainly found in plant-derived purine (Ptrend = 0.001) and, weakly, in animal-derived purine (Ptrend = 0.052). In addition, a U-shaped relationship between purine intake and mortality was observed in males; however, there was no statistically significant dose–response relationship in females. Conclusion: Considering the low-purine-intake levels of the Chinese population, we observed a U-shaped relationship between purine intake and mortality in males, but purine intake may not relate to mortality in females. Future studies should investigate the causal relationship between purine intake and disease burden in China.
    Materialart: Online-Ressource
    ISSN: 2072-6643
    URL: Article
    DOI: 10.3390/nu14091718
    Sprache: Englisch
    Verlag: MDPI AG
    Publikationsdatum: 2022
    ZDB Id: 2518386-2
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  • 2
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    Maternal exposure to housing renovation during the periconceptional period and the risk of offspring with isolated congenital heart disease: a case-control study
    Springer Science and Business Media LLC ; 2023
    In:  Environmental Health Vol. 22, No. 1 ( 2023-04-18)
    Details
    In: Environmental Health, Springer Science and Business Media LLC, Vol. 22, No. 1 ( 2023-04-18)
    Kurzfassung: Congenital heart disease (CHD) is the most prevalent birth defect in recent decades. The aim of this research was to examine the association between maternal housing renovation exposure during the periconceptional period and isolated congenital heart disease (CHD) in their offspring. Methods A multi-hospitals case-control study was conducted from six tertiary A hospitals in Xi’an, Shaanxi, Northwest China based on questionnaires and interviews to address this question. The cases included fetuses or newborns diagnosed with CHD. Controls consisted of healthy newborns without birth defects. In total, 587 cases and 1180 controls were enrolled in this study. The association between maternal periconceptional housing renovation exposure and isolated CHD for offspring was assessed by estimating odds ratios (OR) with multivariate logistic regression models. Results After adjusting for potential confounding variables, it was found that maternal exposure to home improvement projects was associated with a higher probability of isolated CHD in offspring (adjusted OR: 1.77, 95% CI: 1.34, 2.33). Additionally, the risk of the ventricular septal defect (VSD) and patent ductus arteriosus (PDA) for CHD types was significantly associated with maternal exposure to housing renovations (VSD: adjusted OR = 1.56, 95% CI: 1.01, 2.41; PDA: adjusted OR = 2.50, 95% CI: 1.41, 4.45). Conclusions Our study suggests that maternal exposure to housing renovation during the periconceptional period was associated with an increased risk of isolated CHD in offspring. Consequently, it would be beneficial to avoid living in a renovated home from 12 months before pregnancy through the first trimester to lower isolated CHD in infants.
    Materialart: Online-Ressource
    ISSN: 1476-069X
    URL: Article
    DOI: 10.1186/s12940-023-00990-z
    Sprache: Englisch
    Verlag: Springer Science and Business Media LLC
    Publikationsdatum: 2023
    ZDB Id: 2092232-2
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 3
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    Cooking stoves and risk of congenital heart disease in Northwest China: A case-control study
    Elsevier BV ; 2022
    In:  Science of The Total Environment Vol. 816 ( 2022-04), p. 151564-
    Details
    In: Science of The Total Environment, Elsevier BV, Vol. 816 ( 2022-04), p. 151564-
    Materialart: Online-Ressource
    ISSN: 0048-9697
    URL: Article
    DOI: 10.1016/j.scitotenv.2021.151564
    RVK:
    AR 10100
    Sprache: Englisch
    Verlag: Elsevier BV
    Publikationsdatum: 2022
    ZDB Id: 1498726-0
    ZDB Id: 121506-1
    SSG: 12
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 4
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    Habitual intakes of sugar-sweetened beverages associated with gut microbiota-related metabolites and metabolic health outcomes in young Chinese adults
    Elsevier BV ; 2023
    In:  Nutrition, Metabolism and Cardiovascular Diseases Vol. 33, No. 2 ( 2023-02), p. 359-368
    Details
    In: Nutrition, Metabolism and Cardiovascular Diseases, Elsevier BV, Vol. 33, No. 2 ( 2023-02), p. 359-368
    Materialart: Online-Ressource
    ISSN: 0939-4753
    URL: Article
    DOI: 10.1016/j.numecd.2022.10.016
    Sprache: Englisch
    Verlag: Elsevier BV
    Publikationsdatum: 2023
    ZDB Id: 2050914-5
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  • 5
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    The Association Between Dietary Purine Intake and Mortality: Evidence From the CHNS Cohort Study
    Elsevier BV ; 2021
    In:  Current Developments in Nutrition Vol. 5 ( 2021-06), p. 1105-
    Details
    In: Current Developments in Nutrition, Elsevier BV, Vol. 5 ( 2021-06), p. 1105-
    Materialart: Online-Ressource
    ISSN: 2475-2991
    URL: Article
    DOI: 10.1093/cdn/nzab053_098
    Sprache: Englisch
    Verlag: Elsevier BV
    Publikationsdatum: 2021
    ZDB Id: 2908329-1
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 6
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    Maternal Dietary Diversity and Birth Weight in Offspring: Evidence from a Chinese Population-Based Study
    MDPI AG ; 2023
    In:  International Journal of Environmental Research and Public Health Vol. 20, No. 4 ( 2023-02-12), p. 3228-
    Details
    In: International Journal of Environmental Research and Public Health, MDPI AG, Vol. 20, No. 4 ( 2023-02-12), p. 3228-
    Kurzfassung: Studies on the association between maternal dietary diversity and birth weight in offspring are limited, and the impact of such an adjustable factor on birth weight requires investigation to promote neonatal health. This study used data from a larger-scale population-based survey conducted in northwest China to evaluate the association of maternal dietary diversity with neonatal birth weight with a generalized estimating equation model. The results found that maternal dietary diversity was positively associated with neonate birth weight. Furthermore, a higher minimum dietary diversity for women (MDD-W) score during pregnancy was related to a lower risk of low birth weight (LBW) in offspring. The mothers with the highest MDD-W score had a 38% (OR = 0.62, 95% CI: 0.43–0.89) lower risk of LBW than those with the lowest score. Similarly, the mothers with the highest animal-based food dietary diversity score (DDS) had 39% (OR = 0.61, 95% CI: 0.38–0.98) lower risk of LBW in offspring compared with those with the lowest animal-based food DDS. Moreover, the ratio of animal-based food DDS to non-animal-based food DDS could play an important role in predicting neonate birth weight. In conclusion, increasing maternal dietary diversity would improve birth weight in offspring, especially by increasing the intake of animal-based foods among the Chinese population.
    Materialart: Online-Ressource
    ISSN: 1660-4601
    URL: Article
    DOI: 10.3390/ijerph20043228
    Sprache: Englisch
    Verlag: MDPI AG
    Publikationsdatum: 2023
    ZDB Id: 2175195-X
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 7
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    Risk Assessment for Birth Defects in Offspring of Chinese Pregnant Women
    MDPI AG ; 2022
    In:  International Journal of Environmental Research and Public Health Vol. 19, No. 14 ( 2022-07-14), p. 8584-
    Details
    In: International Journal of Environmental Research and Public Health, MDPI AG, Vol. 19, No. 14 ( 2022-07-14), p. 8584-
    Kurzfassung: Objective: This study aimed to develop a nomogram for the risk assessment of any type of birth defect in offspring using a large birth-defect database in Northwest China. Methods: This study was based on a birth-defect survey, which included 29,204 eligible women who were pregnant between 2010 and 2013 in the Shaanxi province of Northwest China. The participants from central Shaanxi province were assigned to the training group, while the subjects from the south and north of Shaanxi province were assigned to the external validation group. The primary outcome was the occurrence of any type of birth defect in the offspring. A multivariate logistic regression model was used to establish a prediction nomogram, while the discrimination and calibration were evaluated by external validation. Results: The multivariate analyses revealed that household registration, history of miscarriages, family history of birth defects, infection, taking medicine, pesticide exposure, folic acid supplementation, and single/twin pregnancy were significant factors in the occurrence of birth defects. The area under the receiver operating characteristic curve (AUC) in the prediction model was 0.682 (95% CI 0.653 to 0.710) in the training set. The validation set showed moderate discrimination, with an AUC of 0.651 (95% CI 0.614 to 0.689). Additionally, the prediction model had a good calibration (HL χ2 = 8.106, p= 0.323). Conclusions: We developed a nomogram risk model for any type of birth defect in a Chinese population based on important modifying factors in pregnant women. This risk-prediction model could be a tool for clinicians to assess the risk of birth defects and promote health education.
    Materialart: Online-Ressource
    ISSN: 1660-4601
    URL: Article
    DOI: 10.3390/ijerph19148584
    Sprache: Englisch
    Verlag: MDPI AG
    Publikationsdatum: 2022
    ZDB Id: 2175195-X
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 8
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    Evaluation of a portable hemoglobin photometer in pregnant women in a high altitude area: a pilot study
    Springer Science and Business Media LLC ; 2009
    In:  BMC Public Health Vol. 9, No. 1 ( 2009-12)
    Details
    In: BMC Public Health, Springer Science and Business Media LLC, Vol. 9, No. 1 ( 2009-12)
    Kurzfassung: Anemia is a widespread public health problem associated with an increased risk of morbidity and mortality, especially in pregnant women. This study examined the agreement between a portable hemoglobin photometer and a laboratory analyzer in determining hemoglobin level in pregnant women. Methods This study recruited 69 pregnant women in Tibet, China. Capillary blood samples were taken to measure hemoglobin concentration using the hemoglobin photometer and the laboratory analyzer. Limit of agreement, concordance and intraclass correlation coefficient were used to evaluate the agreement. Laboratory measurement was considered as the standard reference method. Sensitivity and specificity were calculated to assess the error in screening for anemia. Results Mean difference between the two methods was -2.1 g/l. wide 95% limits of agreement were found (-22.6 g/l to 18.4 g/l). The intraclass correlation coefficient was 0.795, and concordance correlation coefficient was 0.793. Sensitivity and specificity were 94.9% and 76.7% respectively. Positive predictive value was 84.1%, and negative predictive value was 92.0%. Conclusion This hemoglobin photometer is not recommended for determining hemoglobin concentration in pregnancy in a high altitude area.
    Materialart: Online-Ressource
    ISSN: 1471-2458
    URL: Article
    DOI: 10.1186/1471-2458-9-228
    Sprache: Englisch
    Verlag: Springer Science and Business Media LLC
    Publikationsdatum: 2009
    ZDB Id: 2041338-5
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 9
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    Oral rehydration salt use and its correlates in low-level care of diarrhea among children under 36 months old in rural Western China
    Springer Science and Business Media LLC ; 2013
    In:  BMC Public Health Vol. 13, No. 1 ( 2013-12)
    Details
    In: BMC Public Health, Springer Science and Business Media LLC, Vol. 13, No. 1 ( 2013-12)
    Kurzfassung: Since 2000, there has been a decline in the proportion of oral rehydration salts (ORS) therapy in childhood diarrhea. How to sustain and achieve a high level of ORS therapy continues to be a challenge. Methods The data of 14112 households and 894 villages in 45 counties across 10 provinces of Western China were collected in 2005. Generalized estimated equation logistic regression models were used to identify the determinants of ORS use in home-based and village-level care. Results The therapy rate of ORS was 34.62%. This rate in home-based care (HBC) was significantly lower than that in village-level care (VLC), township-level care or county-level-or-above care. The children in the families with several pre-school-aged children (OR = 0.29 95% CI: 0.10, 0.86) or of the smaller age (12 vs 36 months: OR = 0.10 95% CI 0.02, 0.41; 24 vs 36 months: OR = 0.26 95% CI 0.09, 0.77) were less likely to receive ORS therapy against diarrhea in HBC. The children whose family had the habit of drinking boiled water (OR = 2.77 95% CI 1.30-5.91), or whose caretakers received educational materials about childhood diseases (OR = 3.08 95% CI 1.54, 6.16), or who were living in the villages in which village clinics had the available ORS packages (OR = 3.94 95% CI 2.25, 6.90) were more likely to receive ORS therapy against diarrhea in VLC. Conclusion There thus, ORS promoting program should give the highest priority to home care. ORS promoting strategies for low-level care could be strengthened based on children characteristics, the habit of drinking water and the situation of receiving educational material in the families and on the availability of ORS packages in village clinics in rural Western China.
    Materialart: Online-Ressource
    ISSN: 1471-2458
    URL: Article
    DOI: 10.1186/1471-2458-13-238
    Sprache: Englisch
    Verlag: Springer Science and Business Media LLC
    Publikationsdatum: 2013
    ZDB Id: 2041338-5
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 10
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    Maternal exposure to life events during pregnancy and congenital heart disease in offspring: a case-control study in a Chinese population
    Springer Science and Business Media LLC ; 2021
    In:  BMC Pregnancy and Childbirth Vol. 21, No. 1 ( 2021-10-06)
    Details
    In: BMC Pregnancy and Childbirth, Springer Science and Business Media LLC, Vol. 21, No. 1 ( 2021-10-06)
    Kurzfassung: Previous studies have suggested that maternal stress could increase the risk of some adverse pregnancy outcomes, but evidence on congenital heart disease (CHD) is limited. We aimed to explore the association between maternal exposure to life events during pregnancy and CHD in offspring. Methods The data was based on an unmatched case-control study about CHD conducted in Shaanxi province of China from 2014 to 2016. We included 2280 subjects, 699 in the case group and 1581 in the control group. The cases were infants or fetuses diagnosed with CHD, and the controls were infants without any birth defects. The life events were assessed by the Life Events Scale for Pregnant Women , and were divided into positive and negative events for synchronous analysis. A directed acyclic graph was drawn to screen the confounders. Logistic regression was employed to estimate the odds ratio and 95% confidence interval for the effects of life events on CHD. Results After controlling for the potential confounders, the pregnant women experiencing the positive events during pregnancy had lower risk of CHD in offspring than those without positive events (OR = 0.38, 95%CI: 0.30 ~ 0.48). The risk of CHD in offspring could increase by 62% among the pregnant women experiencing the negative events compared to those without (OR = 1.62, 95%CI: 1.29 ~ 2.03). Both effects showed a certain dose-response association. Besides, the positive events could weaken the risk impact of negative events on CHD. Conclusion It may suggest that maternal exposure to negative life events could increase the risk of CHD in offspring, while experiencing positive events could play a potential protective role.
    Materialart: Online-Ressource
    ISSN: 1471-2393
    URL: Article
    DOI: 10.1186/s12884-021-04154-0
    Sprache: Englisch
    Verlag: Springer Science and Business Media LLC
    Publikationsdatum: 2021
    ZDB Id: 2059869-5
    Standort Signatur Einschränkungen Verfügbarkeit
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